Acylex (200mg) 25 Tablets

Acyclovir 200mg Tablet works primarily by targeting and inhibiting the replication of the herpes simplex virus (HSV). It is a nucleoside analog that selectively interferes with viral DNA synthesis. Once inside infected cells, acyclovir is converted into its active form, acyclovir triphosphate. This active form competes with a crucial component called deoxyguanosine triphosphate (dGTP) and selectively inhibits the viral DNA polymerase enzyme. By incorporating itself into the growing viral DNA chain, acyclovir triphosphate causes premature chain termination, effectively halting the replication of the viral genetic material. This mechanism specifically targets actively replicating viral DNA, minimizing its impact on uninfected host cells, making it a potent and selective antiviral agent for the treatment of HSV infections.

Acyclovir 200mg

Antiviral, Antiviral (Herpes)

Tablet

The following are the uses of Acyclovir 200mg Tablet:

• Used for treating initial episodes of genital herpes
• Used for managing recurrent genital herpes
• Effective against herpes simplex virus infections
• Helps suppress recurrent herpes simplex labialis (cold sores)
• Treatment option for chickenpox (varicella)
• Can be used to treat shingles (herpes zoster)
• Provides relief for severe, life-threatening mucocutaneous herpes simplex virus infections
• Used in some cases to manage herpes simplex encephalitis

The following dosage can be followed:

• For adults with genital herpes

• For shingles and chickenpox

• Dosage may vary for specific conditions; consult a healthcare professional.

In the case of an overdose of Acyclovir 200mg Tablets, individuals may experience symptoms such as nausea, vomiting, headaches, and confusion. More severe cases can lead to seizures, kidney damage, and even coma. If an overdose is suspected, it is vital to seek medical assistance promptly. Treatment for an overdose may involve gastric lavage, administration of activated charcoal, and supportive care to manage symptoms and prevent further complications. Timely intervention can significantly impact the outcome.

In the case of a missed dose of Acyclovir 200mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, consult your healthcare provider for guidance, as they may recommend adjusting your dosage or provide specific instructions to ensure you receive the correct amount of medication. It is advisable to set reminders or alarms to help you remember to take your medication on time to avoid missing doses in the future.

To take Acyclovir 200mg Tablets, swallow the tablet whole with a full glass of water, preferably with or after a meal, following the prescribed dosage instructions provided by your healthcare professional, typically one tablet five times a day at 4-hour intervals, excluding overnight.

Following are the conditions/situations when Acyclovir 200mg Tablet should not be taken:

• Should not be taken by individuals with a known allergy to Acyclovir or similar antiviral medications.
• Not suitable for patients with kidney disease or those undergoing dialysis.
• Contraindicated in patients with a history of severe kidney problems caused by Acyclovir.
• Should not be used in patients with a known hypersensitivity to any of the excipients in the formulation.
• Not recommended for individuals with a history of neurological disorders or central nervous system (CNS) depression.
• Avoid in patients with a history of liver disease or impaired liver function.
• Discontinue use if a severe skin reaction or allergic reaction occurs.

The side effects of Acyclovir 200mg Tablet may include:

• Nausea and vomiting
• Headache
• Diarrhea
• Fatigue or drowsiness
• Skin rash or itching
• Dizziness
• Increased liver enzymes (seen in blood tests)
• Confusion (especially in elderly patients or those with kidney problems)

Following are the precautions and warnings for Acyclovir 200mg Tablet:

• Patients with a known allergy to Acyclovir or other antiviral medications should not take this medicine.
• It is crucial to inform your doctor about any kidney or liver-related medical conditions as dosage adjustments might be necessary.
• Elderly patients may be more susceptible to side effects, so close monitoring is recommended.
• Acyclovir may cause dizziness, so caution is advised when performing tasks that require alertness, such as driving or operating machinery.
• This medication should be used with caution in patients with a history of neurological disorders.
• Pregnant and breastfeeding women should consult their doctor before taking Acyclovir, as it may pose risks to the fetus or infant.
• Avoid excessive alcohol consumption while taking this medication as it may increase the risk of certain side effects.
• Discontinue use and seek medical attention if you experience severe or unusual symptoms during treatment.

Following are the drug interactions for Acyclovir 200mg Tablet:

• Probenecid can increase acyclovir levels by reducing its renal excretion, leading to potential toxicity.
• Myelosuppressive effects may be enhanced when combined with other bone marrow suppressants.
• Concomitant use with other nephrotoxic drugs may increase the risk of renal dysfunction.
• Acyclovir may decrease the effectiveness of methotrexate due to competition for renal tubular secretion.
• Administration with zidovudine may increase the risk of hematologic adverse effects.
• Theophylline levels can be increased, potentially requiring dosage adjustments.
• Concurrent use with immunomodulators may theoretically diminish the antiviral effect of acyclovir.

Following are the food interactions for Acyclovir 200mg Tablet:

• Avoid excessive alcohol consumption while taking this medication as it may increase the risk of liver problems and stomach issues.
• Maintain adequate hydration and drink plenty of fluids to support kidney function, especially if you have a history of kidney issues.
• Acyclovir can be taken with or without food, but a consistent routine is recommended to ensure optimal absorption.
• Avoid grapefruit and grapefruit juice as they may interfere with the medication's metabolism, leading to increased drug levels in the body.
• Avoid high-fat meals as they may delay the absorption of Acyclovir, affecting its effectiveness.
• Avoid dairy products if you have a known lactose intolerance, as they may exacerbate gastrointestinal side effects.
• Avoid foods rich in oxalates (e.g., spinach, rhubarb) if you have a history of kidney stones, as Acyclovir can increase the risk of stone formation.

Acyclovir 200mg tablets should be stored in a cool, dry place, preferably at room temperature between 68°F and 77°F (20°C and 25°C). Keep the tablets in their original container, tightly sealed, to protect them from moisture and light. Avoid storing them in the bathroom or kitchen, as these areas may have high humidity and temperature fluctuations. It is crucial to keep the medication away from children and pets to prevent accidental ingestion. Do not use the tablets if the packaging is damaged or shows signs of tampering. Dispose of any unused or expired tablets by following local guidelines for pharmaceutical waste disposal, and do not flush them down the toilet or discard them into the environment.

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Following are the quick tips for Acyclovir 200mg Tablet:

• Take the tablet as directed by your doctor, typically every 4 hours, 5 times a day for optimal results.
• Start the medication as soon as possible after the onset of symptoms for best effectiveness.
• Ensure you complete the full course of treatment, even if you feel better before finishing all the tablets.
• Take the tablet with a full glass of water to aid in swallowing and absorption.
• Maintain a well-hydrated state during treatment to support kidney function.
• Avoid missing doses; if you miss a dose, take it as soon as you remember, unless it's almost time for the next dose.
• Do not double the dose to catch up for a missed one; resume your regular dosing schedule.
• Store the tablets at room temperature, away from light and moisture.