Acylex (800mg) 10 Tablets

Acyclovir 800mg tablets primarily act by inhibiting the replication of herpes simplex virus (HSV) and varicella-zoster virus (VZV). The active component of the tablet, acyclovir, is a synthetic nucleoside analog that mimics the structure of guanosine. Once inside the infected cells, acyclovir is phosphorylated by viral kinases, leading to the formation of acyclovir triphosphate, which is the active form of the drug. Acyclovir triphosphate competitively inhibits viral DNA polymerase, a crucial enzyme for viral DNA replication. By inhibiting this enzyme, acyclovir effectively halts the synthesis of viral DNA, thereby suppressing the replication of HSV and VZV. This mechanism selectively targets viral DNA polymerase, as acyclovir triphosphate lacks the 3'-hydroxyl group necessary for incorporation into host cell DNA, resulting in a more specific antiviral effect.

Acyclovir 800mg

Antiviral medication.

Tablet

The following are the uses of Acyclovir 800mg Tablet:

• Used for treating herpes simplex virus infections, including cold sores and genital herpes.
• Used for managing and reducing the frequency of herpes outbreaks.
• Used to alleviate symptoms of herpes infections, such as pain and itching.
• Used for treating chickenpox, offering symptom relief and reducing the duration of the illness.
• Used for preventing herpes infections in immunocompromised individuals or after organ transplantation.
• Used for treating shingles (herpes zoster) to ease nerve pain and speed up healing.
• Used as a long-term treatment to suppress the herpes virus and reduce transmission.
• Used in severe cases of herpes infections, including those affecting the brain (herpes encephalitis).

The following dosage can be followed:

• For adults with genital herpes

• For shingles and chickenpox

• Dosage may vary for specific conditions; consult a healthcare professional.

In the case of an overdose of Acyclovir 800mg Tablets, it is important to recognize the potential severity of this situation. Symptoms may include kidney problems, seizures, hallucinations, and even loss of consciousness. If you or someone you know has taken more than the prescribed dosage, seek medical advice immediately. Prompt action can help mitigate the risks associated with an overdose, and medical professionals should be consulted to determine the best course of treatment and ensure the patient's well-being.

In the case of a missed dose of Acyclovir 800mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have missed multiple doses, contact your healthcare provider for guidance, as they may recommend adjusting your dosing schedule to ensure you receive the full benefit of the medication. It is best to take the medication as prescribed to maintain its effectiveness.

To take Acyclovir 800mg Tablets, swallow the tablet whole with a full glass of water, preferably with food, as directed by your healthcare professional, typically 2 to 5 times a day, depending on the condition being treated and the severity of the infection.

Here are the conditions or situations when Acyclovir 800mg Tablet should not be taken:

• Avoid using Acyclovir if you have a known allergy or hypersensitivity to Acyclovir or other similar antiviral medications.
• Do not take this medication if you are currently experiencing kidney problems or have a history of kidney disease.
• Contraindicated in patients with a history of severe or life-threatening skin reactions to Acyclovir or similar drugs.
• Should not be used for conditions that are not caused by herpes viruses, as it is specific to treating herpes infections.
• Avoid using Acyclovir if you are breastfeeding, as it can pass into breast milk and may harm the baby.
• Not recommended for individuals with a history of immune system disorders or bone marrow suppression.
• Do not administer Acyclovir to treat chickenpox or shingles in children unless directed by a healthcare professional.

The side effects of Acyclovir 800mg Tablet may include:

• Nausea and vomiting
• Diarrhea
• Headache
• Dizziness
• Fatigue or drowsiness
• Skin rash or itching
• Tremors or shaking
• Confusion or disorientation

Following are the precautions and warnings for Acyclovir 800mg Tablet:

• Avoid use if you have a known allergy to Acyclovir or similar medications.
• Patients with kidney problems should exercise caution and consult a healthcare professional, as dosage adjustments might be necessary.
• Drink plenty of fluids to maintain hydration while taking this medication.
• Inform your doctor if you have a weakened immune system or any pre-existing medical conditions.
• Do not share this medication with others, even if they have similar symptoms.
• Discontinue use and seek medical attention if you experience severe or persistent side effects.
• Elderly patients may require closer monitoring due to potential age-related kidney function decline.

Following are the drug interactions for Acyclovir 800mg Tablet:

• Probenecid can decrease the elimination of acyclovir, leading to increased plasma levels and potential toxicity.
• Nephrotoxic drugs like aminoglycosides or amphotericin B may enhance the risk of kidney-related side effects when used with acyclovir.
• Acyclovir may reduce the effectiveness of Mycophenolate, a drug used in organ transplantation.
• The combination of Acyclovir with other antiviral drugs like Ganciclovir or Zidovudine can increase the risk of bone marrow suppression.
• It may decrease the plasma levels of Theophylline, a medication used in asthma, requiring monitoring and dosage adjustments.
• When taken with other medications that affect the kidneys, such as Vancomycin, the risk of kidney problems may increase.
• Acyclovir can potentially interact with drugs that are eliminated through the kidneys, affecting their clearance and requiring dosage adjustments.

Following are the food interactions for Acyclovir 800mg Tablet:

• Avoid excessive alcohol consumption while taking this medication as it may increase the risk of liver problems and could also impair the effectiveness of the drug.
• Acyclovir absorption is not significantly affected by food, so it can be taken with or without meals.
• However, maintaining a good diet and adequate hydration is essential during treatment to support overall health and kidney function.
• Avoid grapefruit and grapefruit juice as they may affect the metabolism of Acyclovir, potentially leading to increased drug levels in the body.
• Dairy products, especially milk, may decrease the absorption of Acyclovir if taken together. Consider separating them by a few hours.
• Ensure you drink plenty of water to maintain hydration and aid in the efficient excretion of the drug and its metabolites.
• Avoid foods rich in oxalates, such as spinach, rhubarb, and nuts, as Acyclovir can increase the risk of kidney stones, and these foods may contribute to this risk.

Acyclovir 800mg Tablets should be stored in a cool and dry place, preferably at room temperature (68°F to 77°F), and protected from light and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and effectiveness. It is crucial not to expose the medication to high temperatures or humidity, so avoid storing it in the bathroom or near the kitchen stove. Always check the expiration date, and do not use the tablets if they have passed their expiry. Proper disposal of any unused or expired medication is essential; do not flush or pour them down the drain. Consult a pharmacist or healthcare professional for guidance on safe disposal methods, and ensure that the medication is kept out of children's reach to prevent accidental consumption.

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Following are the quick tips for Acyclovir 800mg Tablet:

• Take the tablet as directed by your doctor, typically 2-5 times a day for optimal results.
• Ensure you complete the full course of medication, even if symptoms improve.
• Swallow the tablet whole with a full glass of water; do not crush or chew.
• Maintain a consistent schedule for taking the tablet to maximize effectiveness.
• Avoid missing doses; if you miss one, take it as soon as you remember, but skip if it's almost time for the next dose.
• Stay well-hydrated while taking this medication to reduce the risk of side effects.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.