Aproxen (275mg) 30 Tablets

Naproxen Sodium, at a dosage of 275mg, exerts its therapeutic effects primarily through its role as a nonsteroidal anti-inflammatory drug (NSAID). The mechanism of action involves inhibiting cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. By blocking these enzymes, Naproxen Sodium reduces the production of prostaglandins, which are key mediators of inflammation, pain, and fever. COX-2 inhibition is particularly important, as it is responsible for the formation of prostaglandins at sites of inflammation. This action leads to decreased inflammation, pain relief, and reduction in fever. Naproxen's ability to target these pathways makes it effective in managing various conditions where inflammation and pain are prominent symptoms.

Non-steroidal anti-inflammatory drug (NSAID)

Tablet

The following are the uses of Naproxen Sodium 275mg Tablet:

• Used for relieving acute pain, such as headaches, toothaches, and post-surgical pain.
• Used for reducing inflammation and managing acute gout attacks.
• Used to treat symptoms of rheumatoid arthritis and osteoarthritis.
• Effective for reducing fever and managing common cold symptoms.
• Helps alleviate discomfort and inflammation in minor injuries.
• Used for managing menstrual cramps and associated pain.
• Provides relief from muscle aches and strains.

Follow these dosage instructions:

• Take as per doctor's Prescription.
• Take one tablet per day as your doctor suggests.
• Your doctor will determine the treatment length based on your symptom severity.

In the case of an overdose of Naproxen Sodium 275mg Tablets, symptoms may include severe headache, dizziness, and gastrointestinal issues such as stomach pain, nausea, and vomiting. Overdose can also lead to more serious complications, such as kidney problems, liver damage, and in extreme cases, it may cause rapid and shallow breathing, seizures, and loss of consciousness. It is important to seek medical assistance promptly if an overdose is suspected, as timely treatment can help manage these symptoms effectively.

In the case of a missed dose of Naproxen Sodium 275mg Tablet, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare professional for advice on how to safely adjust your dosing schedule. It is important to adhere to the prescribed dosage to ensure the medication's effectiveness and minimize potential risks.

To take Naproxen Sodium 275mg Tablet, swallow the tablet whole with a full glass of water, preferably with food or after a meal, as directed by your healthcare professional, usually once or twice a day.

Following are the conditions/situations when Naproxen Sodium 275mg Tablet should not be taken:

• Avoid if you have a known allergy to Naproxen or any other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
• Do not take if you have a history of gastrointestinal bleeding or perforation.
• Contraindicated in individuals with severe heart failure or heart disease.
• Should not be used in patients with active stomach or intestinal ulcers.
• Avoid if you have a history of allergic reactions to aspirin or other pain relievers/fever reducers.
• Not recommended for individuals with severe kidney disease or those with a high risk of kidney problems.
• Do not take this medication if you have recently undergone heart bypass surgery (CABG).
• Should be avoided in patients with a history of severe asthma or other respiratory reactions triggered by aspirin or other NSAIDs.
• Contraindicated in individuals with bleeding disorders or those taking blood thinners.

The side effects of Naproxen Sodium 275mg Tablet may include:

• Stomach pain or upset
• Nausea and vomiting
• Heartburn or indigestion
• Dizziness or lightheadedness
• Headache
• Constipation or diarrhea
• Drowsiness
• Skin rash or itching

Following are the precautions and warnings for Naproxen Sodium 275mg Tablet:

• Individuals with a known allergy to naproxen or other NSAIDs should not take this medication.
• Patients with a history of gastrointestinal bleeding, ulcers, or other stomach disorders should use with caution, as it may increase the risk of bleeding.
• This medication may cause an increased risk of cardiovascular events such as heart attack or stroke, especially with long-term use. Monitor for signs and symptoms.
• Naproxen can lead to kidney damage, particularly in patients with existing kidney disease. Regular monitoring is necessary.
• Avoid using this medication during pregnancy, especially during the third trimester, as it may harm the fetus or cause complications.
• Breastfeeding women should exercise caution as naproxen can pass into breast milk and may harm the nursing infant.
• Patients with asthma or chronic lung diseases should be cautious, as naproxen can cause bronchospasm or worsen respiratory conditions.
• Elderly patients may be more susceptible to side effects; dosage adjustments might be required.

Following are the drug interactions for Naproxen Sodium 275mg Tablet:

• Concomitant use with other non-steroidal anti-inflammatory drugs (NSAIDs) may increase the risk of gastrointestinal bleeding and kidney problems.
• Naproxen can decrease the effectiveness of angiotensin-converting enzyme (ACE) inhibitors, a type of blood pressure medication.
• It may reduce the diuretic effect of loop diuretics and thiazide diuretics.
• Naproxen can increase blood pressure, so caution is needed when used with antihypertensive medications.
• Lithium levels may be increased, requiring monitoring to avoid lithium toxicity.
• Combining with anticoagulants/antiplatelet drugs may increase bleeding risk.
• Naproxen can potentially decrease the effectiveness of beta-blockers and methotrexate.

Following are the food interactions for Naproxen Sodium 275mg Tablet:

• Avoid excessive alcohol consumption while taking this medication as it can increase the risk of stomach bleeding and liver toxicity.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Naproxen, leading to increased blood levels and potential side effects.
• Limit caffeine intake as it can increase the risk of stomach irritation and may interfere with the medication's absorption.
• Avoid high-sodium foods, as Naproxen is often combined with sodium, and excessive sodium intake can lead to fluid retention and increased blood pressure.
• Spicy foods should be consumed moderately as they can irritate the stomach lining and potentially worsen gastrointestinal side effects.
• Avoid fatty or greasy foods, as they can slow down the absorption of Naproxen and may increase the risk of gastrointestinal discomfort.
• Dairy products may be consumed but in moderation, as they can sometimes affect the absorption of certain medications, including Naproxen.
• Always ensure you stay well-hydrated while taking Naproxen to reduce the risk of kidney-related complications.

Naproxen Sodium 275mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. Avoid storing them in bathrooms or areas exposed to heat, as temperature fluctuations can impact their effectiveness. Dispose of any unused or expired tablets responsibly; do not flush them or pour them down the drain. Consult your pharmacist or local waste management guidelines for appropriate disposal methods. It is crucial to keep this medication out of children's reach to prevent accidental consumption.

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Following are the quick tips for Naproxen Sodium 275mg Tablet:

• Consult your healthcare provider for the correct dosage and duration of treatment.
• Swallow the tablet whole with a full glass of water, don't crush or chew.
• Take with food or after meals to prevent stomach irritation.
• Avoid alcohol consumption as it may increase the risk of stomach bleeding.
• If you have a history of heart disease, discuss with your doctor before use.
• Do not take other NSAIDs or aspirin concurrently without medical advice.
• Store in a cool, dry place, away from direct sunlight.
• Keep out of reach of children and pets.