Apsin (40mg) 10 Tablets

Famotidine 40mg tablets primarily work by inhibiting the action of histamine at the H2 (histamine-2) receptors in the stomach. This mechanism of action is crucial in reducing gastric acid secretion. Famotidine blocks the H2 receptors, which are responsible for stimulating acid production in the stomach. By binding to these receptors, it suppresses the activation of gastric acid-producing cells, leading to a decrease in the production of stomach acid. This reduction in acid secretion helps alleviate symptoms associated with conditions like gastroesophageal reflux disease (GERD) and peptic ulcers, as it minimizes the corrosive effects of excess acid on the gastrointestinal lining.

Famotidine 40mg

H2-receptor antagonist

Tablet

The following are the uses of Famotidine 40mg Tablet:

• Used for reducing stomach acid production and treating acid reflux.
• Used to relieve heartburn, indigestion, and gastroesophageal reflux disease (GERD).
• Used for healing and preventing stomach ulcers.
• Effective for managing Zollinger-Ellison syndrome, a rare condition causing excessive acid production.
• Used in combination with antibiotics to eradicate Helicobacter pylori (H. pylori) bacteria in the stomach.
• Can be used to prevent and manage aspiration pneumonia in at-risk individuals.
• Provides relief from upper gastrointestinal bleeding caused by stress-related mucosal lesions.

To be taken as per doctor's prescription

In the case of an overdose of Famotidine 40mg Tablets, it is important to recognize the signs and act promptly. Symptoms may include rapid or irregular heartbeat, dizziness, confusion, and seizures. If you suspect an overdose, contact a healthcare professional immediately. They may recommend inducing vomiting or administering activated charcoal to prevent further absorption. Prompt medical attention is necessary to manage potential complications and ensure the patient's well-being.

In the case of a missed dose of Famotidine 40mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen. It is advisable to maintain a consistent schedule to ensure the medication's effectiveness.

To take Famotidine 40mg Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, and do not crush, chew, or break the tablet.

Following are the conditions/situations when Famotidine 40mg Tablet should not be taken:

• Avoid using if you have a known allergy to Famotidine or other similar histamine blockers.
• Do not take this medication if you have severe kidney problems, as dosage adjustments are necessary.
• Not recommended for individuals with acute porphyria, a rare metabolic disorder.
• Should not be used if you are breastfeeding, as it may pass into breast milk.
• Discontinue use if you develop a skin rash or any severe skin reactions.
• Avoid taking Famotidine if you have any stomach or intestinal problems, such as stomach cancer or intestinal blockage.
• Contraindicated in patients with a history of long-term kidney dialysis.

The side effects of Famotidine 40mg Tablet may include:

• Headache
• Dizziness
• Confusion
• Diarrhea
• Constipation
• Muscle or joint pain
• Skin rash or itching

Following are the precautions and warnings for Famotidine 40mg Tablet:

• Do not take this medication if you have a known allergy to Famotidine or other similar drugs.
• Patients with kidney problems should exercise caution and consult a doctor, as dosage adjustments might be necessary.
• Avoid consuming alcohol while taking this medication, as it may increase the risk of side effects.
• If you experience dizziness or drowsiness, refrain from driving or operating heavy machinery.
• Do not exceed the recommended dosage; an overdose can lead to serious health complications.
• Famotidine should be used with caution in elderly patients, as they may be more susceptible to its side effects.
• Consult a healthcare professional if you have any underlying medical conditions or are taking other medications.
• Store Famotidine tablets at room temperature, away from moisture and heat, and keep them out of reach of children.

Following are the drug interactions for Famotidine 40mg Tablet:

• Famotidine can reduce the absorption of certain drugs like atazanavir, delavirdine, and ketoconazole, requiring dosage adjustments for these medications.
• It may decrease the elimination of diazepam, triazolam, and midazolam, leading to increased levels of these drugs in the body.
• Propranolol and other beta-blockers may have reduced absorption when taken with Famotidine.
• Theophylline levels can be increased, requiring dosage adjustments.
• Antacids containing aluminum or magnesium may decrease Famotidine absorption if taken together.
• Alcohol consumption may increase the risk of certain side effects when using Famotidine.
• Drugs metabolized by CYP2D6 and CYP3A4 enzymes may have altered metabolism, affecting their blood levels.

Following are the food interactions for Famotidine 40mg Tablet:

• Famotidine can be taken with or without food, but it is best to take it consistently either with or without meals to maintain a steady level in the body.
• Avoid excessive consumption of acidic foods like citrus fruits, tomatoes, and carbonated beverages, as they can aggravate stomach conditions and potentially reduce the effectiveness of Famotidine.
• Limit or avoid alcohol intake as it can irritate the stomach lining and potentially interfere with the medication's action.
• Grapefruit and grapefruit juice should be consumed cautiously as they can affect the metabolism of Famotidine, leading to increased drug levels in the body and potential side effects.
• Dairy products, especially milk, can reduce the absorption of Famotidine if taken together. Consider separating milk intake from medication by at least 1-2 hours.
• High-fat meals may delay the absorption of Famotidine, but they do not significantly impact its overall effectiveness.
• Avoid caffeine-rich foods and beverages as they can stimulate acid production and potentially counteract the effects of Famotidine.
• Spicy foods can irritate the stomach and potentially worsen symptoms, so it's advisable to reduce their consumption while taking Famotidine.

Famotidine 40mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The medication should be kept in its original container, tightly sealed, to maintain its integrity and prevent contamination. It is crucial not to expose the tablets to extreme temperatures, so avoid storing them in hot or humid environments like bathrooms or near kitchen appliances. Always adhere to the expiration date printed on the packaging, and never use the medication beyond this date. For responsible disposal, do not flush the tablets or pour them down the drain; instead, consult your pharmacist or local waste management guidelines for safe disposal methods. Keep the medication securely stored away from children to prevent accidental consumption.

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Following are the quick tips for Famotidine 40mg Tablet:

• Consult your doctor before taking this medication for personalized advice.
• Swallow the tablet whole with a full glass of water, do not crush or chew.
• Take the tablet on an empty stomach, preferably 1 hour before a meal.
• Avoid consuming alcohol while taking this medication as it may reduce its effectiveness.
• Inform your doctor about all medications you are currently taking to prevent interactions.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Do not share this medication with others, even if their symptoms are similar.