Arcox (60mg) 20 Tablets

Etoricoxib is a selective COX-2 inhibitor, which means it specifically targets the cyclooxygenase-2 (COX-2) enzyme involved in the inflammation and pain pathways. By inhibiting COX-2, etoricoxib blocks the production of prostaglandins, which are key mediators of inflammation and pain. This mechanism of action reduces inflammation and provides pain relief without directly inhibiting the COX-1 enzyme, which is responsible for protecting the stomach lining. As a result, etoricoxib is believed to have a lower risk of gastrointestinal side effects compared to traditional non-selective nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit both COX-1 and COX-2 enzymes.

Etoricoxib 60mg

COX-2 inhibitor

Oral

The following are the uses of Etoricoxib 60mg Tablet:

• Used for relieving pain and inflammation associated with rheumatoid arthritis and osteoarthritis.
• Used for managing acute pain, including postoperative pain and dental pain.
• Used to reduce menstrual pain and discomfort.
• Used in the treatment of ankylosing spondylitis, a form of arthritis affecting the spine.
• Effective for easing gout pain and inflammation.
• Used to alleviate pain and inflammation from sports injuries or sprains.
• Provides relief from long-term pain conditions like chronic back pain or frozen shoulder.

In the case of an overdose of Etoricoxib 60mg Tablets, it is important to seek medical advice promptly. Symptoms may include nausea, vomiting, stomach pain, and potential liver or kidney damage. Do not induce vomiting unless advised by a healthcare professional. Treatment involves supportive care, and in severe cases, medical management in a healthcare facility may be necessary to monitor and address any potential complications.

In the case of a missed dose of Etoricoxib 60mg Tablet, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare professional for guidance on how to resume your medication safely and effectively.

To take Etoricoxib 60mg Tablet, swallow the tablet whole with a glass of water, preferably with or after a meal, exactly as prescribed by your doctor, typically once daily, following the dosage instructions provided by your healthcare professional.

Following are the conditions/situations when Etoricoxib 60mg Tablet should not be used:

• Must not be taken by individuals who have a known allergy or hypersensitivity to Etoricoxib or any other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
• Contraindicated in patients with active stomach or intestinal ulcers or bleeding.
• Not suitable for individuals with severe heart failure or heart disease.
• Should not be used by patients with severe kidney impairment or those on dialysis.
• Avoid using it if you have a history of stroke, mini-stroke (transient ischemic attack), or blood clots in the legs or lungs.
• Do not take this medication if you have uncontrolled high blood pressure.
• Contraindicated in patients with severe liver impairment or active liver disease.
• Not recommended for individuals who have recently undergone coronary artery bypass graft (CABG) surgery.

The side effects of Etoricoxib 60mg Tablet may include:

• Stomach pain or discomfort
• Nausea and vomiting
• Diarrhea
• Headache
• Dizziness
• Skin rashes or itching
• High blood pressure
• Fluid retention and swelling

Following are the precautions and warnings for Etoricoxib 60mg Tablet:

• Not recommended for individuals with a history of allergic reactions to Etoricoxib or other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
• Patients with cardiovascular risks such as heart disease, high blood pressure, or those who have recently had heart surgery should use with caution.
• Kidney function should be monitored regularly, as Etoricoxib may cause renal impairment, especially in elderly patients.
• Avoid using Etoricoxib if you have severe liver impairment, and exercise caution with mild to moderate liver problems.
• Not recommended for pregnant or breastfeeding women unless advised by a healthcare professional.
• This medication may increase the risk of serious gastrointestinal problems like stomach bleeding, especially in long-term use.
• Discontinue use and seek medical attention if you experience symptoms of an allergic reaction, such as rash, itching, or difficulty breathing.
• Consult a doctor if you have a history of hypertension, as blood pressure should be monitored regularly during treatment.

Following are the drug interactions for Etoricoxib 60mg Tablet:

• Etoricoxib may increase the risk of cardiovascular events, such as heart attack or stroke, when used with other drugs like aspirin or anticoagulants, requiring careful monitoring.
• Combining Etoricoxib with other non-steroidal anti-inflammatory drugs (NSAIDs) can increase the risk of gastrointestinal bleeding and ulcers.
• Avoid using Etoricoxib with other selective COX-2 inhibitors or traditional NSAIDs, as it may enhance adverse effects.
• It can interact with diuretics, potentially reducing their effectiveness and increasing the risk of kidney problems.
• ACE inhibitors and angiotensin II receptor blockers may have decreased effectiveness when used with Etoricoxib.
• Lithium levels may be increased when used with Etoricoxib, requiring monitoring to prevent lithium toxicity.
• Etoricoxib may affect the action of antidiabetic medications, potentially altering blood sugar control.
• The risk of bleeding may be increased when Etoricoxib is used with antiplatelet agents.

Following are the food interactions for Etoricoxib 60mg Tablet:

• Avoid excessive caffeine intake, as it can increase the risk of gastrointestinal side effects.
• Grapefruit and grapefruit juice should be consumed with caution, as they may affect the metabolism of Etoricoxib, potentially increasing its levels in the blood.
• Limit alcohol consumption, as it can increase the risk of gastrointestinal bleeding and liver-related side effects.
• Avoid high-fat meals, as they may increase the absorption of Etoricoxib, leading to higher blood levels.
• Maintain a balanced diet, as Etoricoxib may cause sodium and fluid retention, affecting individuals with high blood pressure or heart conditions.
• Avoid potassium-rich foods like bananas and oranges if taking Etoricoxib with diuretics, as it may affect potassium levels.
• Consult a healthcare provider for dietary advice, especially for those with cardiovascular risks, to ensure a safe and effective treatment plan.

Etoricoxib 60mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area, away from direct sunlight, moisture, and heat. It is crucial to keep the tablets in their original packaging, ensuring the container is tightly sealed to maintain their integrity. Do not transfer the medication to a different container, as this may lead to confusion and potential misuse. Regularly check the expiration date on the packaging, and dispose of any expired or unused tablets promptly. When disposing of Etoricoxib, do not flush them down the toilet or discard them into the trash; instead, follow local guidelines for pharmaceutical waste disposal or consult your pharmacist for appropriate methods to ensure environmental safety. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Etoricoxib 60mg Tablet:

• Take the tablet as directed by your doctor, usually once daily.
• Swallow the tablet whole with a full glass of water, do not crush or chew.
• It can be taken with or without food, but taking it with food may reduce stomach upset.
• Avoid alcohol consumption while using this medication to minimize liver-related risks.
• Inform your doctor if you have any liver or kidney issues before taking this medicine.
• Do not take this medication if you are allergic to Etoricoxib or similar painkillers.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.