Augmentin (62.5mg/ml) 20ml Infant Drops

Co-Amoxiclav, a combination of amoxicillin and clavulanic acid, exerts its mechanism of action by inhibiting bacterial cell wall synthesis. Amoxicillin, a penicillin-type antibiotic, works by binding to specific proteins called penicillin-binding proteins (PBPs), which are crucial for forming the bacterial cell wall. This binding interferes with the cross-linking of peptidoglycan chains, a vital component of the cell wall, ultimately leading to cell lysis and bacterial death. Clavulanic acid enhances the effectiveness of amoxicillin by inhibiting beta-lactamase enzymes produced by certain bacteria, which would otherwise break down amoxicillin and render it ineffective. By combining these two components, Co-Amoxiclav broadens the spectrum of activity against a wide range of bacteria, including those that produce beta-lactamase enzymes, making it a potent antibiotic for treating various infections.

Co-Amoxiclav 62.5mg/ml

Penicillin/beta-lactamase inhibitor

drop

The following are the uses of Co-Amoxiclav 62.5mg/ml Drop:

• Used for treating severe and recurrent ear infections, particularly in children.
• Used for respiratory tract infections like pneumonia, bronchitis, and sinusitis.
• Effective against skin and soft tissue infections, including cellulitis and abscesses.
• Used to combat urinary tract infections, especially when caused by resistant bacteria.
• Helps manage dental infections, including abscesses and severe tooth infections.
• Used for bone and joint infections, ensuring thorough bacterial clearance.

To be used as per doctor's prescription

In the case of an overdose of Co-Amoxiclav 62.5mg/ml Drops, it is important to seek medical advice promptly. Symptoms of an overdose may include nausea, vomiting, diarrhea, and stomach discomfort. Treatment for overdose will be based on the specific symptoms that occur, and medical professionals may recommend supportive measures to manage these symptoms. It is crucial to follow the prescribed dosage to prevent adverse effects.

In the case of a missed dose of Co-Amoxiclav 62.5mg/ml Drops, it is important to administer the missed dose as soon as you remember. If it is almost time for the next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to proceed and ensure the correct dosage is administered.

To administer Co-Amoxiclav 62.5mg/ml Drops, gently shake the bottle, use the provided dropper to draw the prescribed amount, and then release the drops into your child's mouth, ensuring they are given as directed by the healthcare professional, typically twice a day, and can be taken with or without food.

Following are the conditions or circumstances when Co-Amoxiclav 62.5mg/ml Drops should not be used:

• Should not be used if the patient has a known allergy to amoxicillin, clavulanic acid, penicillin, or any other beta-lactam antibiotics.
• Contraindicated in patients with a history of severe allergic reactions to any antibiotic in the same class.
• Not suitable for patients with a previous history of liver problems or jaundice caused by amoxicillin/clavulanate.
• Should not be used in patients with mononucleosis.
• Contraindicated in patients with severe kidney disease who require dialysis treatment.
• Not recommended for patients with a history of gastrointestinal diseases, especially colitis or other intestinal disorders.
• Should be avoided in patients with a known history of severe diarrhea or antibiotic-associated diarrhea.

The side effects of Co-Amoxiclav 62.5mg/ml Drops may include:

• Diarrhea
• Nausea and vomiting
• Skin rash or itching
• Dizziness
• Fatigue or tiredness
• Vaginal yeast infections
• Allergic reactions (such as hives, swelling, or difficulty breathing)
• Changes in liver function (rare)

Following are the precautions and warnings for Co-Amoxiclav 62.5mg/ml Drops:

• Do not use if you or your child are allergic to any penicillin or beta-lactam antibiotics, as severe allergic reactions can occur.
• This medication should be used with caution in patients with kidney or liver problems, as dosage adjustments may be necessary.
• Co-Amoxiclav may cause diarrhea, and in rare cases, it can be a sign of a new infection. If severe diarrhea occurs, stop the medication and seek medical advice.
• Prolonged use may lead to the overgrowth of bacteria or fungi, and if new symptoms appear, consult a healthcare professional.
• Caution is advised in patients with a history of gastrointestinal diseases, as it may worsen these conditions.
• Ensure you complete the full prescribed course to prevent antibiotic resistance.
• Store the medication in a cool, dry place, away from direct sunlight, and keep out of reach of children.
• Always consult a healthcare professional if you have any concerns or if symptoms persist or worsen during treatment.

Following are the drug interactions for Co-Amoxiclav 62.5mg/ml Drops:

• Probenecid can reduce the excretion of amoxicillin, increasing the risk of side effects.
• Concurrent use with allopurinol may increase the likelihood of allergic reactions.
• The effectiveness of oral contraceptives may be reduced, so additional contraceptive measures are recommended.
• Co-Amoxiclav can affect the gut flora, potentially reducing the efficacy of oral typhoid vaccine.
• Warfarin levels may be altered, requiring close monitoring of coagulation parameters.
• Myelosuppression may be increased when used with myelosuppressive drugs.
• The risk of nephrotoxicity is higher when combined with nephrotoxic drugs.

Following are the food interactions with Co-Amoxiclav 62.5mg/ml Drops:

• Alcohol consumption should be avoided as it may reduce the effectiveness of the antibiotic and increase the risk of side effects like gastrointestinal discomfort.
• Grapefruit and grapefruit juice should be consumed with caution as they can inhibit the metabolism of amoxicillin, potentially leading to increased levels of the drug in the body.
• Dairy products like milk and yogurt may interfere with the absorption of the antibiotic, especially when taken together. It is best to separate the medication and dairy intake by a few hours.
• High-fiber foods, such as whole grains and legumes, may decrease the absorption of the medication. It is advisable to maintain a balanced diet and ensure adequate fluid intake.
• Vitamin C supplements or citrus fruits rich in vitamin C should be consumed with care as they can affect the stability of amoxicillin.
• Avoid consuming excessive amounts of sugary foods and drinks as they can contribute to dental issues, especially when taking liquid forms of antibiotics.
• Ensure adequate hydration by drinking plenty of water to support the body's overall health during the course of antibiotic treatment.
• There are no specific food restrictions, but maintaining a healthy and varied diet is recommended for optimal recovery.

The storage and disposal of Co-Amoxiclav 62.5mg/ml Drops require careful attention to maintain their effectiveness and ensure safety. Store the medication in a cool, dry place, preferably at room temperature, away from direct sunlight and moisture. Keep the bottle tightly sealed in its original packaging to prevent contamination. Avoid extreme temperatures by not placing the drops near heat sources or in the bathroom, as this can impact their quality. Regularly check the expiration date, and dispose of any unused or expired medication responsibly. Do not dispose of it through household waste or by pouring it down the drain; instead, consult a pharmacist or healthcare professional for guidance on proper disposal methods. Keep the drops out of children's reach to prevent accidental ingestion.

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Following are the quick tips for Co-Amoxiclav 62.5mg/ml Drops:

• Wash your hands before administering the drops to ensure hygiene.
• Check the dropper for any damage and ensure it is clean.
• Administer the prescribed number of drops as directed by your healthcare professional.
• Dispense the drops into the child's mouth directly or mix with a small amount of formula/breast milk.
• Do not mix the drops with hot beverages or acidic drinks.
• Store the bottle in a cool, dry place, away from direct sunlight.
• Always check the expiration date before use.
• If your child's condition doesn't improve or worsens, consult your doctor.