Bludol DS (200mg/ml) 90ml Suspension

Ibuprofen 200mg syrup/suspension primarily exerts its analgesic, anti-inflammatory, and antipyretic effects through its ability to inhibit the synthesis of prostaglandins. It achieves this by blocking cyclooxygenase (COX) enzymes, particularly COX-1 and COX-2. By inhibiting COX enzymes, ibuprofen reduces the production of prostaglandins, which are key mediators of pain, inflammation, and fever. This mechanism helps alleviate pain by reducing the sensitivity of nerve endings, decreases inflammation by inhibiting the production of inflammatory mediators, and lowers body temperature by acting on the hypothalamus to reset the body's thermostat. The COX-2 inhibition is particularly important in reducing inflammation, while the inhibition of COX-1 may contribute to the gastrointestinal side effects associated with ibuprofen use.

Ibuprofen 200mg

Non-steroidal anti-inflammatory drug (NSAID)

Suspension

The following are the uses of Ibuprofen 200mg Syrup/Suspension:

• Used for relieving mild to moderate pain, such as headaches, toothaches, and backaches.
• Used for reducing fever and easing discomfort associated with colds and flu.
• Used for managing minor aches and pains related to muscle strains or sprains.
• Used for alleviating symptoms of arthritis, providing temporary relief from joint pain and inflammation.
• Used for reducing menstrual cramps and discomfort during periods.
• Used for treating pain and inflammation after minor surgical procedures or dental work.
• Used for managing symptoms of cold sores and mouth ulcers, helping to reduce pain and speed up healing.
• Used for providing temporary relief from minor aches and pains associated with common childhood illnesses.

Child's dose is based on age and weight as per doctor's recommendation

In the case of an overdose of Ibuprofen 200mg Syrup/Suspension, symptoms may include nausea, vomiting, stomach pain, and in severe cases, gastrointestinal bleeding. Overdose can lead to serious health complications, particularly in children, due to the high concentration of the active ingredient. Prompt medical intervention is necessary, including contacting a healthcare professional or a poison control center for guidance on managing the overdose effectively and safely.

In the case of a missed dose of Ibuprofen 200mg Syrup/Suspension, it is generally recommended to take the missed dose as soon as you remember, provided it is not too close to the time of your next scheduled dose. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It is important to try to take your medication at the same time each day to maintain consistent levels in your body.

To administer Ibuprofen 200mg Syrup/Suspension, shake the bottle well, then use the provided measuring device to extract the prescribed dose, which should be taken orally as directed by your healthcare professional, either with or without food, ensuring you follow the recommended dosage instructions.

Here is a list of situations when Ibuprofen 200mg Syrup/Suspension should not be used:

• Do not use in individuals with a known allergy or hypersensitivity to Ibuprofen, other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs), or any of the excipients in the syrup/suspension.
• Contraindicated in patients with a history of asthma, urticaria, or allergic-type reactions triggered by aspirin or other NSAIDs.
• Should not be used in individuals with active or recent gastrointestinal bleeding or perforation.
• Not recommended for patients with severe heart failure, severe kidney disease, or severe liver impairment.
• Contraindicated in individuals with a history of gastrointestinal ulcers or bleeding disorders.
• Do not administer to patients who have recently undergone coronary artery bypass graft (CABG) surgery.
• Not suitable for individuals with aspirin-sensitive asthma.
• Should be avoided in patients with a history of severe skin reactions or allergies to medications.

The side effects of Ibuprofen 200mg Syrup/Suspension may include:

• Nausea and vomiting
• Stomach pain or discomfort
• Diarrhea
• Dizziness or vertigo
• Headaches
• Skin rash or itching
• Ringing in the ears (tinnitus)
• Increased blood pressure

Following are the precautions and warnings for Ibuprofen 200mg Syrup/Suspension:

• Do not use in individuals with a known allergy to Ibuprofen or other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
• Avoid long-term use without medical supervision, as it may increase the risk of gastrointestinal bleeding and kidney problems.
• Caution in patients with a history of gastrointestinal issues, as Ibuprofen can cause stomach irritation and bleeding.
• Do not consume excessive alcohol while taking this medication, as it may increase the risk of gastrointestinal bleeding.
• Not recommended for individuals with advanced kidney or liver disease without medical advice.
• Avoid using Ibuprofen during the last trimester of pregnancy, as it may cause complications.
• Always shake the suspension well before use to ensure proper dosage.

Following are the drug interactions for Ibuprofen 200mg Syrup/Suspension:

• May decrease the effectiveness of antihypertensive drugs, leading to elevated blood pressure.
• Increased risk of gastrointestinal bleeding when taken with corticosteroids, aspirin, or other NSAIDs.
• Can reduce the efficacy of diuretics and increase the risk of renal impairment.
• Ibuprofen may elevate lithium levels, increasing the risk of lithium toxicity.
• Anticoagulants like warfarin may have their effects enhanced, requiring close monitoring.
• Increased risk of renal toxicity when used with diuretics, ACE inhibitors, or angiotensin receptor blockers.
• May interact with methotrexate, raising its blood levels and potential toxicity.

Following are the food interactions for Ibuprofen 200mg Syrup/Suspension:

• Ibuprofen should be taken with food or milk to prevent stomach upset and reduce the risk of gastrointestinal side effects.
• Avoid excessive alcohol consumption as it can increase the risk of stomach bleeding and liver damage when combined with Ibuprofen.
• Grapefruit and grapefruit juice may interfere with the metabolism of Ibuprofen, potentially increasing its levels in the body and the risk of side effects.
• Avoid high-sodium foods, as Ibuprofen can cause sodium retention, and a high-salt diet may worsen hypertension.
• Caffeine-rich foods and beverages should be limited as they can increase the risk of nervousness and insomnia, especially when taken close to bedtime.
• Avoid fatty or greasy foods, as Ibuprofen is better absorbed on an empty stomach, and high-fat meals may delay its absorption.
• Consuming a balanced diet rich in vitamins and minerals is advisable, as prolonged use of Ibuprofen may deplete certain nutrients.
• Certain herbal supplements like Ginkgo Biloba, Garlic, and Ginseng may increase the risk of bleeding when combined with Ibuprofen.

Ibuprofen 200mg Syrup/Suspension should be stored in a secure and child-resistant location, preferably in a cool and dry area at room temperature, ensuring it remains out of direct sunlight and moisture. Keep the medication in its original container, tightly sealed, to maintain its integrity and prevent contamination. It is crucial to avoid exposing the syrup to extreme temperatures, so steer clear of storage places like bathrooms, near stoves, or on radiators. Regularly check the expiration date, and if the syrup is past its prime or no longer needed, do not flush it or pour it down the drain. Contact your pharmacist or healthcare provider for guidance on safe disposal methods. Always keep medications out of children's reach to prevent accidental consumption.

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Following are the quick tips for Ibuprofen 200mg Syrup/Suspension:

• Consult a healthcare professional for the right dosage based on your age and medical condition.
• Administer the syrup as directed by your doctor or pharmacist.
• Ensure an accurate dose using the measuring cup provided.
• If the syrup has solidified, bring it to room temperature before use.
• Store the syrup at room temperature, away from direct sunlight or extreme temperatures.
• Avoid taking more than the prescribed dose, and inform your doctor if you experience any adverse effects.
• Do not give this medication to others, even if their symptoms are similar.