Bone-Care C (0.5ug/1000mg) 20 Tablets

Alfacalcidol, a synthetic analog of vitamin D, undergoes hepatic metabolism to form the active metabolite calcitriol, which binds to the vitamin D receptor in target tissues. This binding increases intestinal absorption of calcium and phosphate by regulating the expression of calcium-binding proteins and enzymes involved in calcium transport. Calcium carbonate, a calcium salt, acts as a calcium supplement by dissociating into calcium and carbonate ions in the gastrointestinal tract. Calcium is absorbed, primarily in the duodenum and jejunum, through passive diffusion and active transcellular transport mediated by the action of calcitriol. This combination enhances overall calcium absorption, promoting bone mineralization and maintaining calcium homeostasis.

Alfacalcidol 0.5mcg, Calcium Carbonate 1000mg

Calcium supplement, Vitamin D analogue.

Tablet

The following are the uses of Alfacalcidol 0.5mcg, Calcium Carbonate 1000mg Tablet:

• Used for treating and preventing low levels of calcium in the blood, a condition known as hypocalcemia.
• Used to manage and improve conditions like osteoporosis and rickets, where bone density and strength are compromised.
• Used for promoting proper bone development and growth, especially in individuals with conditions affecting bone health.
• Used to alleviate symptoms related to calcium deficiency, such as muscle cramps and skeletal pain.
• Used in the management of conditions like hypoparathyroidism, where the body produces insufficient parathyroid hormone.
• Used to support calcium absorption and utilization in the body, ensuring optimal bone health.
• Used as a supplementary treatment for various bone-related disorders, aiding in bone healing and fracture recovery.

In the case of an overdose of Alfacalcidol 0.5mcg and Calcium Carbonate 1000mg tablets, symptoms may include nausea, vomiting, weakness, and increased urination. If you suspect an overdose, contact a healthcare professional immediately. Prompt medical attention is necessary as they will provide guidance on the appropriate steps to take, which may include monitoring and supportive care to manage symptoms and ensure the patient's well-being. It is important to act swiftly to prevent potential complications.

In the case of a missed dose of Alfacalcidol 0.5mcg, it is advisable to take the medication as soon as you remember, but if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. For Calcium Carbonate 1000mg tablets, if a dose is missed, take it as soon as possible. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing routine. Do not double the dose to make up for a missed one.

To take Alfacalcidol 0.5mcg and Calcium Carbonate 1000mg Tablet, swallow the tablet whole with a full glass of water, preferably after a meal, once a day or as directed by your healthcare professional.

Following are the conditions/situations when Alfacalcidol 0.5mcg and Calcium Carbonate 1000mg Tablet should not be used:

• Should not be used in individuals with a known allergy to Alfacalcidol, Calcium Carbonate, or any of the excipients in the tablet.
• Contraindicated in patients with hypercalcemia (high levels of calcium in the blood).
• Not recommended for patients with severe kidney disease or impaired kidney function.
• Should not be used in individuals with hypervitaminosis D (excess vitamin D in the body).
• Contraindicated during pregnancy and breastfeeding, unless the potential benefits outweigh the risks.
• Not suitable for patients with hypercalciuria (high levels of calcium in urine) or a history of kidney stones.
• Should be used with caution and under medical supervision in patients with heart disease or high blood pressure.
• Avoid in patients with a history of digestive disorders or intestinal obstruction.

The side effects of Alfacalcidol 0.5mcg, Calcium Carbonate 1000mg Tablet may include:

• Nausea and vomiting
• Constipation or diarrhea
• Loss of appetite
• Increased thirst
• Muscle or joint pain
• Weakness or fatigue
• Elevated calcium levels in the blood (hypercalcemia)
• Allergic reactions (such as rash, itching, or difficulty breathing)

Following are the precautions and warnings for Alfacalcidol 0.5mcg, Calcium Carbonate 1000mg Tablet:

• Patients with known hypersensitivity or allergy to Alfacalcidol, Calcium Carbonate or any of the excipients in the tablet should not take this medication.
• Regular monitoring of calcium and phosphate levels is essential, and dosage adjustments may be required based on laboratory results.
• Individuals with a history of kidney stones or kidney disease should exercise caution, as this medication can increase the risk of stone formation.
• Patients with impaired kidney function may require dosage adjustments and should be monitored closely.
• Do not take other vitamin D supplements or calcium-rich antacids without medical advice, as it may lead to calcium overload.
• This medication may cause dizziness or drowsiness; avoid driving or operating heavy machinery until you know how it affects you.
• Pregnant and breastfeeding women should consult their doctor before taking this medication, as it may have potential risks to the fetus or infant.
• Keep this medication out of reach of children and pets, and store it in a cool, dry place.

Following are the drug interactions for Alfacalcidol 0.5mcg and Calcium Carbonate 1000mg Tablet:

• Anticonvulsants like phenytoin, phenobarbital, and carbamazepine can reduce the effectiveness of Alfacalcidol.
• Thiazide diuretics may enhance the effect of Alfacalcidol, requiring close monitoring.
• Calcium Carbonate can decrease the absorption of tetracycline antibiotics, iron supplements, and levothyroxine.
• Taking Calcium Carbonate with aluminum-containing antacids may result in excessive aluminum levels.
• Bisphosphonates, used for osteoporosis, should be taken at least 30 minutes before Calcium Carbonate to prevent interference with absorption.
• Calcium Carbonate may reduce the absorption of certain antifungal medications, such as itraconazole and ketoconazole.
• Some phosphate binders may interact with Calcium Carbonate, affecting phosphate control in kidney disease patients.

Following are the food interactions for Alfacalcidol 0.5mcg and Calcium Carbonate 1000mg Tablet:

• Alfacalcidol may interact with high-calcium foods like dairy products, calcium-fortified foods, and calcium supplements. It is advisable to maintain a consistent calcium intake and consult a healthcare professional for personalized advice.
• Avoid excessive consumption of oxalate-rich foods like spinach, rhubarb, and beet greens, as oxalates can bind with calcium and affect its absorption.
• Limit alcohol intake as it may interfere with calcium absorption and increase the risk of kidney problems.
• Calcium Carbonate absorption can be hindered by foods high in oxalates and phytic acid, such as whole grains, legumes, and certain vegetables. Consider spacing out calcium intake from these foods.
• Ensure an adequate intake of vitamin D, as it aids in calcium absorption. Consider exposure to sunlight and dietary sources like fatty fish and egg yolks.
• Avoid high-fiber foods or supplements close to taking Calcium Carbonate, as fiber can decrease its absorption.
• Maintain a balanced diet with a variety of foods to ensure a healthy calcium and vitamin D status.
• Always consult a healthcare professional for specific dietary recommendations and to address any concerns regarding food interactions.

Alfacalcidol 0.5mcg and Calcium Carbonate 1000mg Tablets should be stored in a cool and dry place, preferably at room temperature, away from direct sunlight and moisture. Keep the medication in its original container, tightly sealed, to maintain its integrity and prevent contamination. Do not expose the tablets to heat or high temperatures, as this can impact their effectiveness. When discarding unused or expired medication, avoid flushing or pouring them down the drain. Instead, consult a pharmacist or healthcare professional for appropriate disposal methods to ensure environmental safety. Always keep medicines out of children's reach to prevent accidental consumption.

Following are the quick tips for Alfacalcidol 0.5mcg and Calcium Carbonate 1000mg Tablet:

• Take the medication as directed by your doctor; follow the prescription carefully.
• Ensure you understand the dosage instructions and duration of treatment.
• Alfacalcidol can be taken with or without food; follow your doctor's advice.
• Calcium Carbonate tablets should be swallowed whole with a full glass of water.
• Maintain a consistent schedule for taking your medication for better effectiveness.
• Do not crush, chew, or break the tablets; swallow them intact.
• Store the medications at room temperature, away from moisture and direct sunlight.