Btrol (500mg) 10 Capsules

Btrol (500mg) 10 Capsules

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  • Manufacturer Bosch Pharmaceuticals (Pvt.) Ltd.
  • Generic Name Tranexamic Acid

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Laboratory Screening
  • Description

    Tranexamic acid, a synthetic derivative of the amino acid lysine, exerts its primary mechanism of action by competitively binding to plasminogen, thereby blocking its interaction with fibrin. This inhibition prevents the activation of plasmin, an enzyme responsible for the breakdown of fibrin clots. By inhibiting plasmin-mediated fibrinolysis, tranexamic acid promotes the stabilization of existing clots and reduces excessive bleeding. This mechanism is particularly relevant in situations where enhanced fibrinolysis contributes to abnormal or excessive bleeding, making tranexamic acid a valuable agent in various clinical settings to control and prevent excessive blood loss.

  • Ingredients

    Tranexamic Acid
  • Drug Class

    Fibrinolysis inhibitor

  • Dosage Form

    Capsule

  • Uses

    The following are the uses of Tranexamic Acid 500mg Capsule:

    • Used for controlling heavy menstrual bleeding, providing much-needed relief to women suffering from menorrhagia.
    • Used for preventing excessive blood loss during surgeries, ensuring patient safety and improving surgical outcomes.
    • Used in trauma cases to control bleeding, a critical intervention for accidents and injuries.
    • Used post-delivery to manage heavy bleeding, aiding in the recovery process for new mothers.
    • Used in dental procedures to control bleeding, making oral surgeries safer and more comfortable.
    • Used as a treatment for bleeding disorders, offering a vital management option for these conditions.
    • Used to manage bleeding in patients with liver disease, addressing a specific challenge associated with hepatic issues.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Menorrhagia- Take 1 tablet of Tranexamic Acid 500mg 3 times a day at mealtimes.
    • Surgery or dental surgery- Follow your doctor's instructions.
    • Nosebleeds (epistaxis)- Take 500mg 3 times a day.
    • Hereditary angioedema- Follow your doctor's instructions.
  • In case of Overdose

    In the case of an overdose of Tranexamic Acid 500mg Capsules, it is important to recognize the potential symptoms and take appropriate action. These symptoms may include nausea, vomiting, diarrhea, and in severe cases, blood clots or kidney problems. If an overdose is suspected, seek medical advice promptly. Treatment may involve supportive care and monitoring, with the focus on managing symptoms and ensuring the patient's well-being. Timely intervention can help prevent potential complications.

  • Missed Dose

    In the case of a missed dose of Tranexamic Acid 500mg Capsule, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for advice on how to proceed and to ensure you are still receiving the intended benefits of the medication.

  • How To Use

    To take Tranexamic Acid 500mg Capsule, swallow the capsule whole with a full glass of water, preferably with or after a meal, following the dosage instructions provided by your healthcare professional, typically prescribed two to three times a day for a specified duration.

  • When Not to Use

    Here are the conditions or situations when Tranexamic Acid 500mg Capsule should not be used:

    • Avoid using if you have a known allergy or hypersensitivity to Tranexamic Acid or any other related anti-fibrinolytic agents.
    • Not recommended for individuals with active thromboembolic disease or a history of blood clots in the blood vessels.
    • Should not be used if you have a bleeding disorder such as hemophilia.
    • Contraindicated in patients with kidney disease or severe renal impairment.
    • Do not use if you have a history of seizures or epilepsy.
    • Not suitable for individuals with a history of stroke or transient ischemic attack (TIA).
    • Avoid using in patients with color vision impairment or changes, as it may worsen these conditions.
    • Should not be administered to patients with a history of retinal changes or retinal vein thrombosis.
    • Not recommended for individuals with a history of blood clots in the lungs (pulmonary embolism).
    • Contraindicated during pregnancy, especially in the first trimester, unless the potential benefits outweigh the risks.
  • Side Effects

    The side effects of Tranexamic Acid 500mg Capsule may include:

    • Nausea and vomiting
    • Diarrhea
    • Dizziness or lightheadedness
    • Headache
    • Visual disturbances (such as blurred vision)
    • Skin rash or itching
    • Confusion or disorientation
    • Blood clots (rare but serious)
  • Precautions & Warnings

    Following are the precautions and warnings for Tranexamic Acid 500mg Capsule:

    • Do not use if you have a known allergy to Tranexamic Acid or any other ingredients in the capsule.
    • Patients with a history of blood clots or thromboembolic disorders should use with caution, as it may increase the risk of clot formation.
    • Close monitoring is required for patients with renal impairment or undergoing dialysis.
    • Avoid using Tranexamic Acid if you have active bleeding disorders or a history of seizures.
    • Inform your doctor if you are pregnant or breastfeeding, as it may have potential risks for the fetus and infant.
    • This medication may cause dizziness or visual disturbances; avoid driving or operating heavy machinery until you know how it affects you.
    • Elderly patients may be more susceptible to side effects, so dosage adjustments might be necessary.
    • If you are undergoing surgery or dental procedures, inform your healthcare provider about your Tranexamic Acid usage.
  • Drug Interactions

    Following are the drug interactions for Tranexamic Acid 500mg Capsule:

    • Antifibrinolytic effects may be reduced by concurrent use of fibrinolytic agents like streptokinase, urokinase, or tissue plasminogen activators.
    • Increased risk of thrombosis when combined with oral contraceptives, hormone replacement therapy, or other estrogen-containing medications.
    • Blood levels of Tranexamic Acid can be decreased by cholestyramine, potentially reducing its effectiveness.
    • The risk of bleeding may be increased when used with anticoagulants like heparin or warfarin, requiring close monitoring.
    • When combined with nonsteroidal anti-inflammatory drugs (NSAIDs), there is a potential for increased risk of gastrointestinal bleeding.
    • May reduce the effectiveness of thrombolytic therapy, such as alteplase, used in the treatment of acute myocardial infarction or stroke.
    • Tranexamic Acid may interact with anti-platelet drugs like clopidogrel, potentially affecting platelet function and increasing bleeding risk.
  • Food Interactions

    Following are the food interactions for Tranexamic Acid 500mg Capsule:

    • Avoid consuming foods or beverages rich in Vitamin K (like spinach, kale, broccoli, and liver) as they can reduce the effectiveness of Tranexamic Acid by promoting blood clotting.
    • Limit the intake of cranberry juice as it may increase the risk of bleeding when used with Tranexamic Acid.
    • Avoid excessive consumption of foods containing high levels of tyramine (aged cheeses, cured meats, fermented foods) to prevent potential blood pressure elevation.
    • Alcohol consumption should be minimized as it can increase the risk of bleeding and liver-related side effects.
    • Grapefruit and grapefruit juice should be consumed with caution as they may affect the absorption and metabolism of Tranexamic Acid.
    • Avoid high-sodium foods as Tranexamic Acid may increase sodium retention, affecting blood pressure.
    • Consult your doctor if you are on a potassium-rich diet, as Tranexamic Acid may interfere with potassium levels.
    • No significant interactions with regular diets are reported, but maintaining a balanced diet is advised.
  • Storage/Disposal

    Tranexamic Acid 500mg Capsules should be stored in a secure and dry location, away from direct sunlight and moisture. Maintain the capsules in their original packaging, ensuring the container is tightly sealed to prevent exposure to air and potential contamination. Avoid high temperatures or freezing conditions, as these can impact the integrity of the medication. It is crucial not to dispose of the capsules by flushing or pouring them down the drain; instead, follow local guidelines or consult a pharmacist for safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption, and always exercise caution when handling and storing pharmaceutical products. Proper storage and disposal practices are essential to maintain the effectiveness of the medication and ensure safety.

  • Quick Tips, if any

    Following are the quick tips for Tranexamic Acid 500mg Capsule:

    • Take the capsule as directed by your doctor; follow the prescription carefully.
    • Ensure you complete the full course as prescribed, even if you feel better.
    • Swallow the capsule whole with a glass of water; do not crush or chew.
    • Maintain a consistent time for taking the medication each day.
    • Inform your doctor if you have a history of blood clots or kidney problems.
    • Avoid alcohol as it may increase the risk of side effects.
    • Store the capsules in a cool, dry place, away from direct sunlight.
  • Laboratory Screening

    Tranexamic acid is a medication often prescribed to treat or prevent excessive blood loss from the uterus. Lab tests are generally recommended for anyone taking this medication to ensure the user's safety and appropriate usage of the medication. These tests vary depending on individual medical conditions and age, but here are some essential lab tests that may be required for someone taking tranexamic acid:

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