Caflam (50mg) 20 Tablets

Diclofenac potassium is a topical agent used for relieving joint pain in patients with arthritis. It is a non-steroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain associated with arthritis. It achieves this by inhibiting the body's production of chemicals that stimulate inflammation and blood clotting. Diclofenac potassium is also described as potassium salt of diclofenac, a member of the phenylacetic acid class of nonsteroidal anti-inflammatory drugs (NSAIDs). It is widely used in managing painful inflammatory conditions such as osteoarthritis and rheumatoid arthritis, thanks to its potent anti-inflammatory and analgesic properties. Topical diclofenac works by blocking enzymes called cyclooxygenases (COX-1 and COX-2) that are involved in the conversion of prostaglandin H2 (PGH2) to other prostaglandins (PGE2, PGF2alpha, and PGD2). These prostaglandins are released during inflammation and have been implicated in dysregulation of the inflammatory response. By blocking their production, diclofenac potently reduces inflammation and pain. Arthritis is a common disorder characterized by painful inflammation of the joints, and diclofenac Potassium 50mg is often used as a safe and effective way to relieve arthritis-related pain and inflammation.

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Nonsteroidal Anti-inflammatory Drug (NSAID)

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Tablet

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Unveiling its multifaceted uses and transformative applications as follows:

• Relieves pain and reduces inflammation
• Treats various types of arthritis, including osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis
• Reduces menstrual cramps
• Eases pain and reduces inflammation associated with wisdom tooth extraction
• Treats eye pain and inflammation of the eye after surgery
• Helps with neck pain caused by muscle strain or sprain

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Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For pain and fever- 50 to 100 mg every 4 to 6 hours (maximum of 200 mg in a day)
• For osteoarthritis- 50 to 150 mg daily in divided doses
• For rheumatoid arthritis- 50 to 150 mg daily in divided doses
• For ankylosing spondylitis- 50 to 150 mg daily in divided doses
• For dysmenorrhea- 50 mg initially, then 25 mg every 6 hours (maximum of 150 mg in a day)
• For migraine- 50 to 100 mg every 6 to 8 hours (maximum of 150 mg in a day)
• For postoperative pain- 50 to 100 mg every 4 to 6 hours (maximum of 150 mg in a day)

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Taking too much of the medicine diclofenac potassium 50mg can make you very sick. Symptoms include vomiting, diarrhea, nausea, constipation, and headaches. In extreme cases, it can even cause a coma or death. If you believe you've taken too much, seek medical attention right away.The medical staff will provide supportive care, like helping to monitor fluids, maintaining your body temperature, and treating any complications. They may wash out your stomach if it recently ingested the drug, and give you activated charcoal within a certain amount of time since ingestion. Depending on how severe the overdose is, they may give you additional medications to help with any symptoms or complications.

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If you miss a dose of diclofenec potassium 50mg, it is crucial to take it as soon as you can. However, if it is almost time for your next dose, skip the missed dose and stay on your regular schedule. Do not take a double dose. If you are uncertain about whether to take a missed dose or how to take it, reach out to your physician or pharmacist for advice. It is imperative to only take diclofenac potassium 50mg as directed and in the amount prescribed to you by your doctor. Overdosing can be harmful to your health. If you have more questions or concerns about missing a dose of diclofenec potassium 50mg, consult your doctor.

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Diclofenac potassium should be taken orally as directed by your healthcare provider, usually with a full glass of water. It can be taken with or without food, but taking it with food or milk may help reduce stomach upset. Swallow the tablet whole without crushing or chewing it. Follow the prescribed dosage and timing carefully, and do not exceed the recommended dose.

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Discerning instances where this medication may not be appropriate:

• Allergy to NSAIDs
• Stomach issues
• Kidney dysfunction

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Unraveling the side effects lurking behind this medications are as follows:

• Gastrointestinal irritation
• Upper respiratory tract symptoms
• Cardiovascular events
• Kidney dysfunction or failure.
• Bleeding events.
• Allergic reactions
• Wound healing impairment.
• Intestinal perforation or bleeding.
• Life-threatening skin reactions
• Muscle or joint pain.
• Headaches.
• Dizziness.
• Tinnitus.
• Hearing impairment.
• Impaired vision.
• Ringing in the ears.
• Unusual weight gain or loss.

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Here are some important precautions and warnings regarding Diclofenac potassium:

• Diclofenac potassium, a nonsteroidal anti-inflammatory drug (NSAID), carries significant risks of cardiovascular (CV) and gastrointestinal (GI) adverse events.
• Clinical trials have demonstrated an increased risk of serious cardiovascular thrombotic events, including myocardial infarction (MI) and stroke, particularly with prolonged use or higher doses.
• This cardiovascular risk applies to patients with and without known CV disease, though individuals with preexisting conditions face a higher absolute risk.
• Concurrent use of aspirin does not reduce this CV risk and may increase the risk of serious GI events.
• Diclofenac is contraindicated after coronary artery bypass graft (CABG) surgery and should be used cautiously in post-MI patients, as studies indicate a higher incidence of reinfarction and death in these populations.
• NSAIDs, including diclofenac, may cause serious GI complications, such as bleeding, ulcers, and perforation, even without warning symptoms.
• Risk factors for GI events include a history of ulcers, prolonged NSAID use, and concomitant use of corticosteroids, anticoagulants, or SSRIs.
• Diclofenac has also been associated with hepatotoxicity, renal toxicity, hypertension, heart failure, and severe skin reactions, including Stevens-Johnson syndrome.
• To minimize risks, diclofenac should be used at the lowest effective dose for the shortest duration, with close monitoring for signs of toxicity, especially in high-risk patients.

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Drug interactions with diclofenac potassium include:

• Anticoagulants (e.g., warfarin) (may increase the risk of bleeding- monitor INR closely)
• Other NSAIDs (e.g., ibuprofen) (may increase the risk of gastrointestinal bleeding and ulceration)
• Antihypertensives (e.g., ACE inhibitors, diuretics) (may reduce the effectiveness of blood pressure-lowering medications)
• Corticosteroids (e.g., prednisone) (may increase the risk of gastrointestinal adverse effects)
• Lithium (may increase lithium levels and risk of toxicity- monitor serum levels)
• Methotrexate (may increase the toxicity of methotrexate- monitor for adverse effects)
• CYP2C9 inhibitors (e.g., fluconazole) (may increase diclofenac levels and risk of side effects)
• Cyclosporine (may increase the risk of renal toxicity)
• Antidiabetic agents (e.g., metformin) (no significant interaction but monitor for any changes in blood glucose)

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Diclofenac potassium is a medication used to treat pain and inflammation, recommended to be taken orally in tablet form. It is important to adhere to the storage instructions to ensure the medication is effective and safe. The tablets should be stored at room temperature in a cool, dry place, and kept away from heat and light. The container should always be tightly closed and out of the reach of children. For any questions or concerns about storing this medication, it is advised to consult a medical professional, such as your doctor or a pharmacist, who can provide you with proper guidance. They can direct you on the correct storage and handling of the medication to ensure its effectiveness and safety.

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