Capcidol (0.025%) 20ml Lotion

Capsaicin, the active component in Capsaicin Lotion, acts by selectively binding to transient receptor potential vanilloid subtype 1 (TRPV1) receptors, which are predominantly found in sensory neurons involved in pain signaling. Upon application, capsaicin causes a reversible activation and desensitization of these TRPV1 receptors. Initially, it triggers a burning sensation by stimulating the nerve fibers, but with repeated exposure, it leads to a reduction in the sensitivity of the nerves to pain stimuli. This desensitization occurs through a process known as defunctionalization, where the nerve fibers become less responsive to various stimuli, resulting in a decrease in pain perception. The mechanism involves the depletion of substance P, a neuropeptide involved in pain transmission, from the nerve endings, thereby disrupting the pain signaling pathway.

Capsaicin

Topical Analgesic

Lotion

The following are the uses of Capsaicin Lotion:

• Used for treating nerve pain and muscle soreness.
• Used for managing arthritis and joint pain.
• Used for relieving headaches and migraines.
• Used for reducing inflammation and swelling.
• Used for easing symptoms of skin conditions like psoriasis.
• Used for providing temporary relief from minor aches and sprains.
• Used for stimulating blood circulation in targeted areas.
• Used for offering localized pain management.

In the case of an overdose of Capsaicin Lotion, it is important to recognize the signs of excessive exposure, which may include severe skin irritation, redness, and a burning sensation. If applied topically, immediately wash the affected area with mild soap and water to reduce the concentration of capsaicin. Discontinue use and consult a healthcare professional for further guidance if symptoms persist or worsen.

In the case of a missed dose of Capsaicin Lotion, it is generally recommended to apply the lotion as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular application schedule. It is important not to double the dose to make up for a missed one. If you frequently forget doses, consider setting reminders or asking someone to remind you to ensure consistent use of the medication. Consult your healthcare provider if you have any concerns or questions regarding missed doses.

To apply Capsaicin Lotion, wash your hands thoroughly, then gently massage a thin layer of the lotion onto the affected area, ensuring you avoid contact with eyes, nose, mouth, and broken skin, and wash your hands again after application.

Following are the conditions/situations when Capsaicin Lotion should be avoided:

• Do not use on open wounds, cuts, or broken skin.
• Avoid contact with eyes, nose, mouth, and other sensitive areas.
• Do not apply to irritated or inflamed skin.
• Contraindicated in individuals with a known allergy to capsaicin or any of the lotion's components.
• Should not be used on skin areas with eczema, psoriasis, or other skin conditions without medical advice.
• Avoid using on skin that will be exposed to extreme heat or cold, such as a hot bath, sauna, or freezing temperatures.
• Do not cover the treated area with a bandage or plastic wrap unless directed by a healthcare professional.
• Do not use on skin that is already sensitive to heat or has impaired temperature sensation.
• Not suitable for infants, children, or individuals who cannot communicate discomfort.
• Avoid using on skin areas with impaired circulation or peripheral vascular disease.
• Discontinue use if the skin becomes excessively red, swollen, or blistered.

The possible side effects of Capsaicin Lotion may include:

• Skin irritation and redness at the application site
• Burning or stinging sensation
• Itching or rash
• Dryness or flaking of the skin
• Temporary numbness or tingling
• Swelling or inflammation
• Allergic reactions (skin rash, hives, difficulty breathing)
• Eye irritation if accidentally exposed to eyes

Following are the precautions and warnings:

• Capsaicin Lotion should be used with caution on sensitive skin areas, and a patch test is recommended before widespread application.
• Avoid contact with eyes, nose, mouth, and other mucous membranes as it can cause irritation and burning sensation.
• Wash your hands thoroughly after applying the lotion to prevent accidental transfer to sensitive areas.
• Do not apply to open wounds, cuts, or irritated skin.
• It may cause temporary skin redness, stinging, or burning, especially in the first few days of use. Discontinue use if these symptoms persist or worsen.
• Avoid using Capsaicin Lotion on large areas of the body or under occlusive dressings, as this may increase the risk of side effects.
• Keep out of reach of children and pets. Store in a cool, dry place away from direct sunlight.

Following are the drug interactions for Capsaicin Lotion:

• Capsaicin may enhance the absorption of other topical medications when applied together, potentially increasing their effects.
• It can interact with local anesthetics, potentially altering their effectiveness.
• Avoid using Capsaicin with other skin irritants or sensitizers, as this may increase the risk of skin reactions.
• Medications that affect blood circulation to the skin, such as vasodilators or vasoconstrictors, may influence the absorption and effects of Capsaicin.
• Capsaicin should be used with caution in combination with medications that affect nerve function, as it may have additive effects.
• Topical steroids, when used with Capsaicin, may increase the risk of skin atrophy or other steroid-related side effects.
• Some analgesics, especially those applied topically, may have their absorption and effects altered when used concurrently with Capsaicin.

Following are the food interactions to be aware of when using Capsaicin Lotion:

• Avoid contact with eyes, nose, mouth, and sensitive mucous membranes. Wash hands thoroughly after application to prevent accidental transfer.
• Capsaicin can cause a burning sensation and irritation if it comes into contact with broken skin or open wounds. Avoid applying it to these areas.
• Eating spicy foods containing capsaicin can enhance the burning sensation and discomfort, especially if you have sensitive skin.
• Hot or acidic foods might aggravate the skin, increasing the likelihood of irritation and burning.
• Dairy products like milk or yogurt can provide some relief from the burning sensation as they contain casein, which helps neutralize capsaicin's effects.
• Avoid touching your face or eyes after handling spicy peppers, as capsaicin from your hands can cause irritation.
• Capsaicin-infused food products like hot sauces or chili oils can cause skin irritation if not handled with care during consumption.

Storage and disposal of Capsaicin Lotion require careful attention to ensure safety and maintain the integrity of the product. Store the lotion in a cool, dry place, preferably at room temperature, away from direct sunlight and moisture. Keep the container tightly sealed to prevent contamination and maintain its effectiveness. Avoid extreme temperatures, such as storing it in the bathroom or near heat sources, as this can impact the lotion's quality. Regularly check the expiration date, and if the lotion is past its prime, dispose of it responsibly. Do not dispose of it through household plumbing; instead, seek guidance from a pharmacist or healthcare professional for the recommended disposal methods. Lastly, ensure the lotion is kept securely away from children to prevent accidental exposure.

Following are the quick tips for Capsaicin Lotion:

• Before application, perform a skin test to check for sensitivity.
• Wash your hands thoroughly before and after applying the lotion.
• Apply a thin layer to the affected area, gently massaging it into the skin.
• Avoid contact with eyes, nose, mouth, and other sensitive areas.
• Do not wrap or bandage the treated area unless directed by a healthcare professional.
• Wash hands immediately if you accidentally get the lotion in your eyes or on sensitive skin.
• Store the lotion at room temperature, away from direct sunlight and heat.