Cardace (10mg) 20 Tablets

Enalapril 10mg Tablet primarily exerts its therapeutic effects through the inhibition of the angiotensin-converting enzyme (ACE). By blocking ACE, Enalapril prevents the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. This inhibition leads to decreased angiotensin II levels, resulting in reduced vasoconstriction and lower aldosterone secretion from the adrenal cortex. Consequently, blood pressure is lowered due to the relaxation of arterial smooth muscle, and the kidneys increase the excretion of sodium and water, further contributing to the reduction in blood pressure. This mechanism of action makes Enalapril effective in treating hypertension and heart failure by improving cardiovascular function and reducing the workload on the heart.

Enalapril 10mg

Angiotensin-converting enzyme (ACE) inhibitor

Tablet

The following are the uses of Enalapril 10mg Tablet:

• Used for treating high blood pressure (hypertension).
• Used to lower blood pressure and reduce the risk of heart attacks or strokes.
• Used for managing heart failure by improving heart function.
• Used to treat left ventricular dysfunction after a heart attack.
• Used to reduce the risk of kidney problems in patients with diabetes and high blood pressure.
• Used to slow the progression of kidney disease in patients with hypertension.
• Used for improving survival rates in patients with heart failure.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• High blood pressure- Enalapril is commonly used as an antihypertensive drug and is given in a dose of 2.5-20 mg once daily to adults who have this condition.
• Heart failure- Enalapril is typically given in a lower dose of 2.5-5 mg once daily to adults who have heart failure. The dose may be increased depending on the person's condition and response to the medication.

In the case of an overdose of Enalapril 10mg Tablets, several symptoms may occur, including a significant drop in blood pressure, leading to lightheadedness or dizziness. Other potential effects include kidney impairment, resulting in decreased urine output, and elevated potassium levels in the blood, which can cause irregular heart rhythms. Prompt medical intervention is necessary to manage these symptoms effectively and prevent potential complications from the overdose. It is essential to seek professional advice for appropriate treatment and monitoring.

In the case of a missed dose of Enalapril 10mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this may increase the risk of side effects. It is generally recommended to take the missed dose within 8 to 12 hours of the original scheduled time, but consult your healthcare provider for specific guidance on managing missed doses. They can provide tailored advice based on your medical history and the reason for your Enalapril prescription.

To take Enalapril 10mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional.

Following are the conditions when Enalapril 10mg Tablet should not be used:

• Should not be taken by individuals who are allergic to Enalapril or other ACE inhibitors.
• Contraindicated in patients with a history of angioedema (swelling of the face, throat, or tongue) after taking ACE inhibitors.
• Not recommended for pregnant or breastfeeding women, as it can cause harm to the developing fetus or infant.
• Should not be used in individuals with severe kidney disease or those on dialysis.
• Contraindicated in patients with bilateral renal artery stenosis.
• Not suitable for individuals with a history of hereditary angioedema.
• Should be avoided in patients with a condition called collagen vascular disease, such as systemic lupus erythematosus (SLE).
• Should not be used in patients with low blood pressure (hypotension).
• Contraindicated during the second and third trimesters of pregnancy.

The side effects of Enalapril 10mg Tablet may include:

• Dizziness
• Fatigue or weakness
• Headache
• Nausea and vomiting
• Diarrhea
• Dry cough
• Skin rash or itching
• Altered taste sensation

Following are the precautions and warnings for Enalapril 10mg Tablet:

• Do not take this medication if you have a history of angioedema or are allergic to Enalapril or other ACE inhibitors.
• Patients with kidney disease or a history of kidney problems should be monitored regularly as Enalapril can affect kidney function.
• Inform your doctor if you have liver disease as dosage adjustments may be necessary.
• Caution is advised for elderly patients, as they may be more susceptible to side effects and require closer monitoring.
• Enalapril may cause dizziness or lightheadedness, especially when standing up from a sitting or lying position; patients should rise slowly to prevent falls.
• Avoid potassium supplements and potassium-rich foods unless directed by a doctor, as Enalapril can increase potassium levels.
• This medication may cause a decrease in white blood cell count, which can increase the risk of infections; monitor for signs of infection.
• Regular blood tests may be required to monitor kidney function and blood cell counts while on this medication.

Following are the drug interactions for Enalapril 10mg Tablet:

• Lithium and potassium-sparing diuretics (e.g., spironolactone, triamterene) may increase the risk of hyperkalemia when used with Enalapril.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce the antihypertensive effect of Enalapril and may increase the risk of kidney damage.
• The combination of Enalapril with other angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) may lead to excessive blood pressure drop.
• Enalapril may increase the blood concentration of lithium, leading to lithium toxicity.
• The diuretic effect of Enalapril can be reduced by non-steroidal anti-inflammatory drugs (NSAIDs) and COX-2 inhibitors.
• When used with immunosuppressants like sirolimus or cyclosporine, Enalapril may increase their blood levels, potentially causing toxicity.
• Enalapril may decrease the elimination of procainamide and hydralazine, increasing their blood levels and risk of side effects.
• Caution is advised when combining Enalapril with other medications affecting blood pressure, as it may lead to excessive hypotension.

Following are the food interactions for Enalapril 10mg Tablet:

• Avoid excessive salt intake, as it can reduce the effectiveness of Enalapril in controlling blood pressure.
• Potassium-rich foods like bananas, oranges, and spinach should be consumed in moderation, as Enalapril may increase potassium levels in the body.
• Avoid potassium supplements unless prescribed by a doctor, as it can lead to hyperkalemia.
• Limit alcohol consumption as it may decrease the effectiveness of Enalapril and increase the risk of dizziness and hypotension.
• Do not use salt substitutes or potassium supplements without medical advice, as it may lead to an imbalance in electrolyte levels.
• Avoid high-protein diets, as they may reduce the absorption of Enalapril, affecting its efficacy.
• Grapefruit and grapefruit juice should be consumed cautiously, as they may increase the blood levels of Enalapril, potentially leading to an increased risk of side effects.

Enalapril 10mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. It is crucial not to expose the medication to extreme temperatures, so avoid storing it in hot or humid environments like bathrooms or near heat sources. Always adhere to the expiration date on the packaging, and when it's time to discard the medication, do not flush or pour it down the drain. Instead, consult a pharmacist or healthcare professional for appropriate disposal methods to ensure environmental safety. Keep the tablets out of children's reach to prevent accidental consumption.

Following are the quick tips for Enalapril 10mg Tablet:

• Consult your doctor before starting this medication and provide a complete medical history.
• Take the tablet as directed by your doctor, typically once or twice daily.
• Consume the tablet with a full glass of water, preferably at the same time each day.
• Do not crush, chew, or break the tablet; swallow it whole for effective absorption.
• If you experience dizziness, especially when standing up, rise slowly to prevent falls.
• Inform your doctor about all the medications you are taking to avoid potential interactions.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.

Enalapril Maleate is a medication primarily used to treat high blood pressure and heart failure. An important point to note is that lab tests are not usually required when taking this medication, unlike some other blood pressure medications. However, it is possible that Enalapril may induce abnormalities in blood tests, so it is crucial to inform your doctor if you are taking this medication when undergoing any lab tests as it can cause elevated potassium levels in the blood and low sodium levels. These abnormalities may require your doctor to adjust your medication or investigate other potential causes. Therefore, it is recommended that you inform your doctor about all the medications you are taking, including Enalapril, when undergoing any medical tests or procedures.