Cardnit (6.4mg) 30 Tablets

Glyceryl Trinitrate, the active ingredient in the 6.4mg tablet, exhibits its therapeutic effects primarily through its conversion to nitric oxide (NO) in the body. This process occurs after the drug is metabolized, leading to the relaxation of vascular smooth muscles. Nitric oxide acts as a potent vasodilator, causing the dilation of both arterial and venous blood vessels. By promoting vasodilation, Glyceryl Trinitrate reduces the workload on the heart, decreases arterial pressure, and enhances blood flow, particularly in the coronary arteries. This mechanism of action is crucial in the treatment of angina pectoris and other cardiovascular conditions where improved blood flow and reduced cardiac stress are essential.

Glyceryl Trinitrate 6.4mg

vasodilator

Tablet

The following are the uses of Glyceryl Trinitrate 6.4mg Tablet:

• Used for managing and preventing chest pain (angina) episodes.
• Effective in relaxing and widening blood vessels, improving blood flow to the heart.
• Useful for treating high blood pressure in emergency situations.
• Administered to reduce the heart's workload and oxygen demand.
• Prescribed to manage symptoms in heart failure and heart attacks.
• Can be used to treat and prevent cluster headaches.
• Provides rapid relief during angina attacks.

To be used as per doctor's prescription

In the case of an overdose of Glyceryl Trinitrate 6.4mg Tablets, symptoms may include severe and persistent headaches, dizziness, fainting, and a rapid or pounding heartbeat. It is important to seek medical advice promptly if an overdose is suspected. Treatment involves monitoring vital signs, managing symptoms, and providing supportive care. Prompt action can help mitigate the potential risks associated with an overdose of this medication.

In the case of a missed dose of Glyceryl Trinitrate 6.4mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen. It is crucial to maintain consistency in taking this medication as prescribed by your healthcare professional.

To use Glyceryl Trinitrate 6.4mg Tablet, place the tablet under your tongue and allow it to dissolve completely, preferably without swallowing, as directed by your healthcare provider or pharmacist, ensuring the prescribed dosage is followed.

Here are the conditions and situations when Glyceryl Trinitrate 6.4mg Tablet should not be used:

• Must not be taken by individuals with a known allergy to Glyceryl Trinitrate or nitrates.
• Contraindicated in patients with severe anemia, as it can worsen oxygen supply to vital organs.
• Should not be used in individuals with recent head injury or increased intracranial pressure.
• Not recommended for patients with narrow-angle glaucoma.
• Avoid using in patients with certain heart conditions like severe aortic stenosis, hypertrophic obstructive cardiomyopathy, or constrictive pericarditis.
• Contraindicated during the acute phase of a heart attack (acute myocardial infarction).
• Should not be used in patients with severe hypotension (very low blood pressure).
• Not suitable for individuals with a recent stroke or cerebral hemorrhage.

The side effects of Glyceryl Trinitrate 6.4mg Tablet may include:

• Severe headaches or migraines.
• Dizziness or lightheadedness.
• Flushing or redness of the skin.
• Palpitations or increased heart rate.
• Nausea and vomiting.
• Weakness or fatigue.
• Skin rashes or itching.
• Drop in blood pressure.

Following are the precautions and warnings for Glyceryl Trinitrate 6.4mg Tablet:

• Do not use if you are allergic to glyceryl trinitrate or any other nitrates.
• This medication is for oral use only. Do not crush, chew, or swallow the tablet whole, as it is designed to dissolve under the tongue.
• It can cause severe headaches, especially during the initial days of treatment. Consult your doctor if the headache persists or becomes severe.
• Exercise caution if you have a history of low blood pressure, as this medication may cause a sudden drop in blood pressure.
• Patients with heart conditions, especially those with hypertrophic cardiomyopathy, should use it with caution and under medical supervision.
• Avoid alcohol consumption while taking this medication as it may exacerbate side effects.
• Elderly patients may be more sensitive to the effects of this medication, so close monitoring is necessary.
• Always carry the medication with you, and inform medical personnel that you are taking it in case of emergencies.

Following are the drug interactions for Glyceryl Trinitrate 6.4mg Tablet:

• Phosphodiesterase inhibitors like Sildenafil can increase the vasodilatory effects and risk of hypotension.
• Combining with other vasodilators, such as hydralazine, may cause excessive blood pressure drop.
• The hypotensive effect of Glyceryl Trinitrate can be reduced by alpha-adrenergic agonists like Midodrine.
• ACE inhibitors and beta-blockers may enhance the anti-anginal effects but also increase the risk of low blood pressure.
• Alcohol consumption may lead to increased vasodilation and potential hypotension.
• Drugs that release nitric oxide, like sodium nitroprusside, can have additive effects and increase the risk of severe hypotension.
• Medications metabolized by the liver, such as oral contraceptives, might have altered effects when taken with Glyceryl Trinitrate.

Following are the food interactions for Glyceryl Trinitrate 6.4mg Tablet:

• Alcohol consumption should be avoided as it can increase the risk of hypotension and dizziness, especially when combined with the medication's vasodilatory effects.
• Grapefruit and grapefruit juice are to be avoided as they can inhibit the metabolism of Glyceryl Trinitrate, leading to increased drug levels in the body and potentially causing severe side effects.
• High-fat meals may delay the absorption of the drug, potentially reducing its effectiveness, so it is best to take the medication on an empty stomach.
• Caffeine-rich foods and beverages like coffee, tea, and energy drinks may increase heart rate and blood pressure, counteracting the medication's effects and should be consumed in moderation.
• Salt and sodium-rich foods should be limited as they can counteract the medication's effect on reducing blood pressure and may increase fluid retention.
• Avoid large meals and heavy, fatty foods as they can slow down the absorption of the medication and may increase the risk of gastrointestinal side effects.
• It is advisable to maintain a healthy, balanced diet to support overall cardiovascular health while taking this medication.
• Always consult your healthcare provider for specific dietary recommendations based on your medical condition.

Glyceryl Trinitrate 6.4mg Tablets should be stored in a cool, dry area, preferably at room temperature, away from light and moisture. The medication should be kept in its original container, tightly sealed, to maintain its integrity and prevent contamination. It's crucial not to expose the tablets to high temperatures or direct sunlight as this can degrade their quality. Always check the expiry date on the packaging, and never use the medication if it's expired. When disposing of unused tablets, do not flush them or throw them into the trash. Instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods. Ensure that the medication is kept securely away from children to prevent accidental consumption.

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Following are the quick tips for Glyceryl Trinitrate 6.4mg Tablet:

• Consult a doctor for proper dosage and usage instructions based on your medical condition.
• Ensure you understand how and when to take the tablet for maximum effectiveness.
• Do not crush or chew the tablet; swallow it whole with water.
• Maintain a consistent schedule for taking the tablet as directed by your doctor.
• Avoid missing doses; take the tablet at evenly spaced intervals.
• Inform your doctor if you experience severe headaches or prolonged dizziness.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Keep the medication out of the sight and reach of children.