Children's Panadol (80mg/0.8ml) 30ml Infact Drops

Paracetamol, the active ingredient in Paracetamol 80mg/0.8ml Drops, works by inhibiting the synthesis of prostaglandins, which are involved in the mediation of pain and inflammation in the body. It primarily exerts its analgesic and antipyretic effects in the central nervous system. Paracetamol blocks cyclooxygenase (COX) enzymes, specifically COX-2, which are responsible for the production of prostaglandins. By reducing the production of these inflammatory mediators, paracetamol helps to alleviate pain and lower elevated body temperature. The exact mechanism by which paracetamol selectively blocks COX-2 in the central nervous system while having minimal effect on peripheral COX enzymes is not fully understood, but it contributes to its therapeutic effects and favorable safety profile at recommended doses.

Analgesic/Antipyretic

Drop

The following are the uses of Paracetamol 80mg/0.8ml Drop:

• Used for reducing fever in children, especially when they are uncomfortable or irritable due to high body temperature.
• Used for relieving mild to moderate pain, such as headaches, toothaches, earaches, and post-vaccination pain.
• Used to ease discomfort and pain associated with teething in infants and toddlers.
• Used for managing aches and pains related to colds and flu, helping to alleviate symptoms.
• Used as an antipyretic to break a fever and maintain a normal body temperature during illnesses.
• Used as an analgesic to provide temporary relief from various types of pain, ensuring comfort.
• Can be used as an adjunct to other medications to enhance their effectiveness in managing pain and fever.

In the case of an overdose of Paracetamol 80mg/0.8ml Drops, the severity of symptoms can vary depending on the amount ingested. Symptoms may include nausea, vomiting, abdominal pain, and potential liver damage. Prompt medical intervention is essential, as treatment options include administering activated charcoal and sometimes even hospital admission for further monitoring and supportive care. It is crucial to seek medical advice for specific guidance and management in overdose cases.

In the case of a missed dose of Paracetamol 80mg/0.8ml Drops, it is recommended to administer the medication as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for the missed one. If you miss multiple doses, consult your healthcare professional for guidance on how to get back on track with the medication regimen.

To administer Paracetamol 80mg/0.8ml Drops, gently shake the bottle, draw out the prescribed dose using the dropper provided, and release the drops directly into the mouth or mix with a small amount of food or liquid as directed by your healthcare professional, ensuring the full dose is taken.

Following are the conditions or situations when Paracetamol 80mg/0.8ml Drops should not be used:

• Do not use if the patient is allergic to paracetamol or any other ingredients in the drops.
• Avoid using in patients with severe liver or kidney disease.
• Do not administer if the patient is currently taking other medications containing paracetamol to avoid overdose.
• Not suitable for infants or children who cannot be given the correct dose based on their weight.
• Contraindicated in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency.
• Do not use if the seal of the bottle is broken or the drops are discolored.
• Should not be used if the patient has a history of severe allergic reactions to medications.

The side effects of Paracetamol 80mg/0.8ml Drops may include:

• Skin rash or itching
• Nausea and vomiting
• Stomach pain
• Loss of appetite
• Unusual bleeding or bruising
• Dark urine
• Yellowing of skin or eyes (jaundice)
• Allergic reactions (such as difficulty breathing, swelling of the face or throat)

Following are the precautions and warnings for Paracetamol 80mg/0.8ml Drops:

• Do not exceed the recommended dosage, as Paracetamol overdose can cause severe liver damage.
• Consult a healthcare professional before use if you have liver or kidney disease, as they may need to monitor your liver function.
• Avoid prolonged use without medical supervision, especially in patients with underlying medical conditions.
• Do not use for an extended period to treat pain or fever without consulting a healthcare provider.
• Inform your doctor if you are taking any other medications, as Paracetamol may interact with certain drugs.
• This medication is intended for oral use only. Do not inject or use intravenously.
• Keep out of reach of children. Accidental ingestion of large quantities can be dangerous.
• Always read the package insert or consult a healthcare professional for specific instructions and precautions for your individual needs.

Following are the drug interactions for Paracetamol 80mg/0.8ml Drop:

• May interact with other central nervous system depressants like opioids, benzodiazepines, or alcohol, leading to increased sedation and respiratory depression.
• Can prolong the effects of anticoagulants such as warfarin, requiring close monitoring of blood clotting time.
• When used with other hepatotoxic drugs, it may increase the risk of liver damage, especially in high doses or prolonged use.
• Paracetamol can potentially decrease the effectiveness of anti-epileptic drugs, requiring close monitoring of seizure control.
• The effect of Paracetamol may be reduced by uricosuric agents, which increase the excretion of paracetamol's metabolites.
• May increase the risk of bleeding when taken with antiplatelet drugs like clopidogrel or aspirin.
• Concomitant use with certain antibiotics like isoniazid or rifampicin can increase the metabolism of paracetamol, potentially reducing its effectiveness.

Following are the food interactions for Paracetamol 80mg/0.8ml Drop:

• Avoid excessive caffeine intake as it may increase the metabolism of Paracetamol, potentially reducing its effectiveness.
• Grapefruit and grapefruit juice should be consumed with caution as they can inhibit liver enzymes, leading to higher concentrations of Paracetamol in the body.
• Alcohol consumption should be limited as it can increase the risk of liver damage, especially with long-term Paracetamol use.
• Avoid high-fat meals as they may delay the absorption of Paracetamol, affecting the onset of its action.
• Maintain a balanced diet to support overall health and aid in the body's natural healing processes.
• Stay well-hydrated, especially when taking this medication, to facilitate its distribution and elimination.
• Avoid excessive consumption of foods containing high levels of tyramine, such as aged cheeses, cured meats, and fermented foods, as they may interact with Paracetamol in the liver.

The proper storage and disposal of Paracetamol 80mg/0.8ml Drops are crucial for safety. Keep the drops in a cool, dry place, away from sunlight and moisture, ideally at room temperature. Ensure the bottle is tightly sealed to maintain its integrity and prevent contamination. Avoid extreme temperatures by not storing near heat sources like stoves or radiators, as this can impact the medication's effectiveness. Always check the expiration date, and if the drops are no longer needed or have expired, do not flush or pour them down the drain. Consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep all medications securely stored and out of children's reach to prevent accidental consumption.

Following are the quick tips for Paracetamol 80mg/0.8ml Drop:

• Administer the drops as directed by your doctor or pharmacist for effective pain and fever relief.
• Check the dropper for any blockages and clean it regularly to ensure accurate dosing.
• Give the correct dose based on the child's weight and age; do not exceed the recommended dosage.
• Store the drops at room temperature, away from direct sunlight and moisture.
• Discard any unused or expired medication safely, keeping it out of the reach of children.
• If symptoms persist or worsen, consult your healthcare provider immediately.
• Do not mix the drops with other medications unless advised by a healthcare professional.