Clycin-T (1%) 30ml Lotion

Clindamycin lotion works by inhibiting bacterial protein synthesis. Its primary mechanism of action is through binding to the 50S subunit of the bacterial ribosome, which subsequently interferes with the translation process. By doing so, Clindamycin prevents the formation of essential proteins required for bacterial growth and replication. This action is highly selective for bacterial ribosomes, as it does not affect the protein synthesis machinery in human cells, making it an effective treatment for certain skin infections caused by susceptible bacteria. The topical application of Clindamycin lotion allows for a localized effect, targeting the bacteria directly on the skin surface and within the hair follicles.

Clindamycin

Lincosamide antibiotic.

Lotion

The following are the uses of Clindamycin Lotion:

• Used for treating acne and reducing the number of pimples and blackheads.
• Used for skin infections caused by certain bacteria, helping to control the infection and relieve symptoms.
• Used for controlling the growth of bacteria on the skin, preventing further infection.
• Used for managing folliculitis, an inflammation of hair follicles, to reduce inflammation and eliminate bacteria.
• Used for impetigo, a highly contagious bacterial skin infection, to speed up healing and prevent spreading.
• Used for erysipelas, a type of skin infection, to treat the bacterial infection and alleviate symptoms.
• Used for cellulitis, a bacterial skin infection, to combat the infection and promote healing.
• Used for preventing surgical site infections when applied before certain surgeries, reducing the risk of post-operative complications.

To be applied once daily as a thin layer on affected area or as prescribed by doctor

In the case of an overdose of Clindamycin Lotion, it is important to note that this topical medication is generally well-tolerated. However, if a large amount is accidentally ingested, it may lead to gastrointestinal symptoms such as nausea, vomiting, or diarrhea. If this occurs, it is advisable to seek medical advice promptly. Promptly consulting a healthcare professional can provide guidance and ensure appropriate management of any potential adverse effects.

In the case of a missed dose of Clindamycin Lotion, it is important to apply it as soon as you remember. However, if it's almost time for your next dose, skip the missed application and continue with your regular schedule. Do not apply extra lotion to make up for the missed dose, as this may increase the risk of skin irritation. If you frequently miss doses, it is advisable to set reminders or use a medication tracker to help you stay on track with your treatment plan. Always consult your healthcare provider if you have any concerns or questions regarding missed doses.

To apply Clindamycin Lotion, clean and dry the affected skin area, then gently massage a thin layer of the lotion onto the skin, ensuring complete coverage, and avoid getting the lotion in your eyes, nose, or mouth.

Following are the conditions/situations when Clindamycin Lotion should not be applied:

• Do not use if you have a known allergy or sensitivity to clindamycin or lincomycin.
• Avoid using on open wounds, sunburns, or severely damaged skin.
• Not recommended for individuals with a history of regional enteritis, ulcerative colitis, or antibiotic-associated colitis.
• Should not be applied to areas of skin affected by eczema or other skin conditions without consulting a doctor.
• Avoid using if you have a history of allergic reactions to topical medications.
• Do not use if the lotion is discolored or contains particles.

The side effects of Clindamycin Lotion may include:

• Skin irritation at the application site
• Dryness or peeling of the skin
• Redness or mild burning sensation
• Itching or rash
• Swelling or inflammation
• Diarrhea (if ingested accidentally)
• Allergic reactions (skin redness, swelling, hives)
• Gastrointestinal discomfort (nausea, vomiting)

Following are the precautions and warnings:

• Clindamycin Lotion is intended for external use only and should not be ingested or applied to mucous membranes.
• Avoid contact with eyes, nose, and mouth. If contact occurs, rinse thoroughly with water.
• Discontinue use and consult a healthcare professional if you experience severe irritation, redness, or swelling at the application site.
• This medication may cause skin sensitivity; minimize exposure to sunlight and use sunscreen when outdoors.
• Do not use on broken or damaged skin, and avoid applying to open wounds.
• Keep out of reach of children and pets. Store in a cool, dry place, away from direct sunlight.
• Inform your doctor if you have a history of gastrointestinal diseases or any other medical conditions before using this medication.

Following are the drug interactions for Clindamycin Lotion:

• Erythromycin and other macrolide antibiotics may increase the risk of gastrointestinal side effects when used topically with clindamycin.
• Topical benzoyl peroxide products can reduce the antibacterial effectiveness of clindamycin lotion.
• Combining clindamycin with erythromycin or other lincosamide antibiotics may increase the risk of antibiotic resistance.
• The absorption of topical tretinoin can be increased by clindamycin lotion, potentially causing skin irritation.
• Topical retinoids, such as adapalene or tazarotene, may cause increased skin dryness or irritation when used with clindamycin lotion.
• Alcohol-based products might cause irritation if applied with clindamycin lotion.
• Caution is advised when using clindamycin lotion with other topical acne treatments, as it may increase skin sensitivity.

Following are the food interactions for Clindamycin Lotion:

• Avoid consuming alcohol during the treatment period as it may cause increased skin dryness and irritation.
• Grapefruit and grapefruit juice consumption should be limited as they can affect the absorption and metabolism of Clindamycin, potentially leading to increased side effects.
• Avoid spicy foods as they may exacerbate skin irritation and worsen any existing skin conditions.
• Dairy products like milk and cheese might reduce the absorption of Clindamycin; consider separating the medication and dairy intake by a few hours.
• High-fat meals can delay the absorption of Clindamycin, so it's best to apply the lotion at least an hour before or after a fatty meal.
• Caffeinated beverages might increase skin sensitivity, so it's advisable to limit coffee and tea intake during treatment.
• Sugary foods and beverages can promote bacterial growth, potentially reducing the effectiveness of Clindamycin.

Clindamycin Lotion should be stored with care to maintain its effectiveness and ensure safe disposal. Keep the lotion in a cool, dry place, preferably at room temperature, away from direct sunlight and heat sources like ovens or radiators. It's crucial to store it in its original container, tightly sealed, to prevent contamination. Always check the expiration date, and if the lotion is past its prime or no longer needed, proper disposal is essential. Avoid flushing it down the toilet or pouring it into drains; instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep the medication out of children's reach to prevent accidental exposure.

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Following are the quick tips for Clindamycin Lotion:

• Apply a thin layer to the affected area as directed by your doctor or pharmacist.
• Cleanse the skin gently before applying the lotion.
• Wash your hands before and after application to avoid spreading bacteria.
• Use the lotion as soon as you remember if you miss a dose, but skip missed doses if it's almost time for the next application.
• Do not double the dose to make up for a missed one.
• Avoid applying the lotion near your eyes, nose, mouth, or open wounds.
• Inform your doctor if your condition doesn't improve or worsens after a few days of using the lotion.