Crafilm (1g/5ml) 120ml Syrup

Sucralfate syrup or suspension works primarily by adhering to the ulcer sites and forming a protective barrier. Its active component, sucralfate, reacts with stomach acid to form a paste-like substance that binds to the ulcerated or eroded areas of the gastrointestinal tract. This protective coating acts as a barrier, preventing further damage from stomach acid, pepsin, and bile salts, which are known to irritate and delay the healing process of ulcers. By creating this protective layer, sucralfate promotes healing and reduces pain and inflammation associated with ulcers. The mechanism of action is localized and does not involve systemic absorption, making it particularly effective for treating ulcers and other gastrointestinal lesions.

Antiulcer agent

Suspension

The following are the uses of Sucralfate Syrup/Suspension:

• Used for treating stomach ulcers and duodenal ulcers.
• Used for managing gastrointestinal bleeding.
• Used for healing and protecting the stomach lining.
• Used to relieve symptoms of acid reflux and heartburn.
• Used for treating and preventing esophageal damage.
• Used for managing side effects of radiation therapy in cancer patients.
• Used for promoting healing after stomach or intestinal surgery.

Follow these dosage instructions:

• Take as per doctor's Prescription.
• Shake the bottle well before use.
• The suspension is recommended to use twice daily, ususally 1 hour before meals.

In the case of an overdose of Sucralfate Syrup/Suspension, it is important to recognize the signs and symptoms. These may include gastrointestinal discomfort, nausea, and vomiting. If a significant amount is ingested, it can lead to more severe symptoms such as abdominal pain, constipation, and in rare cases, respiratory distress. Prompt medical evaluation is necessary to determine the appropriate treatment, which may involve managing symptoms and providing supportive care.

In the case of a missed dose of Sucralfate Syrup/Suspension, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It is important to maintain a consistent dosing schedule for the medication to be most effective. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track.

To take Sucralfate Syrup/Suspension, shake the bottle well, measure the prescribed dose with a measuring device, and administer it orally, following the dosing instructions provided by your healthcare professional, typically taken 2 to 4 times a day, 1 hour before meals and at bedtime.

Following are the conditions or situations when Sucralfate Syrup/Suspension should not be used:

• Do not use in patients with known hypersensitivity or allergy to Sucralfate or any of its excipients.
• Not recommended for patients with a history of gastrointestinal obstruction or suspected bowel perforation.
• Contraindicated in patients with severe kidney disease or end-stage renal disease.
• Should not be used in patients who are unable to swallow or have difficulty swallowing.
• Not suitable for infants or young children who cannot reliably swallow the medication.
• Avoid use in patients with a history of chronic lung disease, as it may increase the risk of respiratory complications.
• Do not administer if the patient has a nasogastric tube in place, as it may clog the tube.

The side effects of Sucralfate Syrup/Suspension may include:

• Constipation
• Dry mouth
• Nausea and vomiting
• Diarrhea
• Headache
• Dizziness
• Skin rash or itching
• Difficulty breathing (rare)

Following are the precautions and warnings for Sucralfate Syrup/Suspension:

• Avoid using this medication if you have a known allergy to Sucralfate or any other ingredients in the syrup.
• Patients with kidney disease should exercise caution and inform their doctor, as the dosage may need adjustment.
• Sucralfate should be taken 1-2 hours before or after other medications, as it can bind to certain drugs and reduce their effectiveness.
• If you are taking any other prescription or over-the-counter medications, inform your doctor to prevent potential drug interactions.
• Do not use this medication to treat symptoms that may be caused by more serious conditions. Seek medical attention if symptoms persist or worsen.
• This medication may cause constipation, so patients with a history of bowel obstruction or gastrointestinal issues should use it with caution.
• Sucralfate Syrup/Suspension should be used with caution in children, and only under medical supervision.

Following are the drug interactions for Sucralfate Syrup/Suspension:

• Antacids containing aluminum or magnesium can decrease the absorption of Sucralfate, so separate the administration of these medications by at least 2 hours.
• Sucralfate may reduce the absorption of certain medications like tetracycline antibiotics, digoxin, phenytoin, and fluoroquinolones, so take these drugs at least 2 hours before or after Sucralfate.
• Avoid using Sucralfate with systemic fluoride due to the potential risk of reduced fluoride absorption and decreased effectiveness of fluoride treatment.
• The bioavailability of certain medications, including ciprofloxacin, levofloxacin, and ketoconazole, may be decreased when used with Sucralfate.
• Drugs that rely on an acidic environment for absorption (e.g., azole antifungals, iron salts) may have reduced absorption when used concurrently with Sucralfate.
• Sucralfate can bind to levothyroxine, reducing its absorption, so separate the administration of these medications by at least 4 hours.
• The absorption of quinolone antibiotics like ciprofloxacin and norfloxacin may be impaired when taken with Sucralfate, so ensure a sufficient time gap between doses.

Following are the food interactions for Sucralfate Syrup/Suspension:

• Sucralfate may bind to certain foods, especially dairy products, resulting in reduced absorption of the medication. Avoid taking it with milk, yogurt, or cheese.
• Avoid consuming antacids containing aluminum, magnesium, or calcium within 30 minutes before or after taking Sucralfate, as they can interfere with its effectiveness.
• Grapefruit juice should be consumed cautiously as it may affect the metabolism of Sucralfate, potentially altering its effectiveness.
• Alcohol intake is not recommended with Sucralfate as it may irritate the stomach lining and delay the healing process.
• Avoid taking Sucralfate with meals, especially those high in protein, as it can decrease the absorption of the medication. Take it 2 hours before or after meals.
• Certain foods rich in phosphates, such as carbonated beverages, may decrease the effectiveness of Sucralfate.
• Caffeinated beverages like coffee and tea may stimulate acid production and potentially reduce the efficacy of Sucralfate.

Sucralfate Syrup/Suspension should be stored in a cool and dry environment, preferably at room temperature, ensuring protection from direct sunlight and moisture. Keep the medication securely sealed in its original container to maintain its integrity and prevent contamination. Avoid storing it in areas prone to temperature fluctuations like bathrooms or near heat-emitting appliances. Regularly check the expiration date, and if the syrup is no longer required or has expired, proper disposal is crucial. Do not dispose of it through household waste or drainage systems; consult your pharmacist or healthcare professional for appropriate disposal practices. Additionally, ensure the medication is kept securely away from children to prevent accidental consumption.

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Following are the quick tips for Sucralfate Syrup/Suspension:

• Always follow your healthcare professional's instructions for dosage and duration.
• Shake the bottle vigorously before each use to ensure a well-mixed suspension.
• Administer the syrup with a suitable measuring device to ensure accurate dosing.
• Take the syrup at evenly spaced intervals to maintain a consistent level in your system.
• Avoid taking it with dairy products or antacids; these can interfere with its effectiveness.
• Store the syrup at room temperature, away from direct sunlight and moisture.
• Contact your doctor if you experience any unusual side effects or if symptoms persist.