Curine (0.025%) 15ml Eye Drops

Naphazoline is a sympathomimetic amine that primarily acts on alpha-adrenergic receptors in the blood vessels of the eye. Its mechanism of action involves the stimulation of these receptors, leading to vasoconstriction. When applied topically to the eye in the form of drops, naphazoline binds to the alpha-adrenergic receptors located on the blood vessels of the conjunctiva and cornea. This binding triggers a series of intracellular events, resulting in the contraction of the vascular smooth muscle. The constriction of these blood vessels reduces redness and inflammation by decreasing blood flow to the affected area. The selective action of naphazoline on the alpha-adrenergic receptors contributes to its effectiveness in alleviating ocular redness without significantly affecting other physiological processes.

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Drop

The following are the uses of Naphazoline Drop:

• Used for temporarily relieving redness and soreness in the eyes caused by minor eye irritations.
• Used for treating eye inflammation and itching due to allergies, hay fever, or pink eye (conjunctivitis).
• Used for reducing eye swelling and redness after eye surgeries or procedures.
• Used for narrowing blood vessels in the eye to reduce redness and congestion.
• Used for providing temporary relief from eye strain and fatigue.
• Used for preventing redness of the eye before eye examinations.
• Used for controlling excessive tearing in certain eye conditions.

To be used as per doctor's advice

In the case of an overdose of Naphazoline Drops, it is important to act swiftly. If the medication is accidentally ingested, particularly by children, contact a healthcare professional or poison control center promptly. They will provide specific guidance based on the circumstances of the overdose, including the amount ingested and the individual's health condition. Quick action can help mitigate potential adverse effects.

In the case of a missed dose of Naphazoline Drops, it is important to administer the medication as soon as you remember. If it is almost time for your next dose, skip the missed one and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare professional for advice on how to proceed, as they may recommend adjusting the dosage or provide further instructions to ensure the medication's effectiveness.

To administer Naphazoline eye drops, gently tilt your head back, pull down the lower eyelid to create a pocket, and hold the dropper above the eye; release one drop into the pocket, then close your eye gently and apply light pressure to the inner corner of the eye for 1-2 minutes to prevent drainage.

Following are the conditions/situations when Naphazoline eye drops should not be used:

• Do not use if you have an allergy or sensitivity to Naphazoline or any other ingredients in the eye drop formulation.
• Contraindicated in individuals with narrow-angle glaucoma or those at risk of developing narrow-angle glaucoma.
• Should not be used if you have severe dry eyes or a history of severe dry eye syndrome.
• Not recommended for individuals who have recently undergone eye surgery or have an eye injury.
• Avoid using these drops if you have untreated high blood pressure or uncontrolled cardiovascular disease.
• Do not use if you have a history of stroke or transient ischemic attack (TIA or mini-stroke).
• Contraindicated in individuals with severe kidney disease or those on dialysis.
• Should not be used in infants or young children without medical advice.

The side effects of Naphazoline Eye Drops may include:

• Burning or stinging sensation in the eyes.
• Temporary blurred vision.
• Eye redness or irritation.
• Increased eye discharge.
• Dryness or discomfort in the eyes.
• Headache or dizziness.
• Increased sensitivity to light (photophobia).
• Allergic reactions, including itching, swelling, or rash around the eyes.

Following are the precautions and warnings for Naphazoline Eye/Nasal Drops:

• Avoid using Naphazoline if you have narrow-angle glaucoma or untreated open-angle glaucoma, as it can worsen these conditions.
• Do not use this medication for more than 3-4 days consecutively without consulting a healthcare professional. Prolonged use can lead to rebound congestion.
• If you have a history of heart disease, high blood pressure, diabetes, or thyroid problems, consult a doctor before use as Naphazoline may affect these conditions.
• Naphazoline may cause temporary blurred vision after application. Avoid driving or operating machinery until your vision is clear.
• Children under 6 years of age should not use this medication unless prescribed by a doctor.
• If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes after use before reinserting them.
• If symptoms persist or worsen, or if redness and irritation continue for more than 72 hours, discontinue use and consult a healthcare provider.

Following are the drug interactions for Naphazoline Drop:

• Beta-blockers, Concomitant use may decrease the effectiveness of beta-blockers due to the vasoconstrictive properties of Naphazoline.
• Monoamine Oxidase Inhibitors (MAOIs), Can lead to a hypertensive crisis when used together.
• Tricyclic Antidepressants, May increase the risk of hypertension and other cardiovascular effects.
• Selective Serotonin Reuptake Inhibitors (SSRIs), Potential for increased blood pressure.
• Antihypertensives, Naphazoline may counteract the effects of these medications, requiring close monitoring.
• Clonidine, Can interfere with its hypotensive action.
• Sympathomimetic Drugs, Combined use may result in increased cardiovascular side effects.

Following are the food interactions for Naphazoline Drops:

• Naphazoline may cause increased sensitivity to alcohol, so it is advisable to avoid or limit alcoholic beverages.
• Caffeine-containing products such as coffee, tea, energy drinks, and certain soft drinks should be consumed with caution as they may enhance the effects of Naphazoline, potentially causing increased blood pressure and heart rate.
• Grapefruit and grapefruit juice should be used with caution as they can affect the metabolism of some medications, although specific studies with Naphazoline are not available.
• Foods high in sodium (salt) should be consumed in moderation as Naphazoline can cause sodium retention, leading to increased blood pressure.
• Spicy foods may cause nasal irritation and discomfort, especially if you have a sensitive nasal lining, so it's best to avoid them if you experience such irritation.
• Dairy products may increase mucus production, which could potentially affect the effectiveness of Naphazoline drops.
• Staying well-hydrated by drinking plenty of water is generally recommended to maintain overall health and may help alleviate dry mouth or throat irritation, which can sometimes be associated with the use of nasal decongestants.

Naphazoline eye drops should be stored properly to maintain their effectiveness and safety. Keep the bottle tightly closed in a cool, dry place, preferably at room temperature, and away from direct sunlight and heat sources like radiators or stoves. Protect the drops from freezing temperatures as well. Always check the expiration date on the packaging, and do not use the drops if they have expired. When it's time to discard the medication, do not pour it down the drain or flush it; instead, follow local guidelines for pharmaceutical waste disposal or consult your pharmacist for safe disposal options. Keep the drops out of children's reach to prevent accidental exposure.

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Following are the quick tips for Naphazoline Drops:

• Wash your hands before using the eye drops to maintain hygiene.
• Tilt your head back, gently pull down your lower eyelid, and apply the prescribed number of drops into the eye.
• Close your eyes gently after drop administration and avoid blinking rapidly to allow the medication to absorb.
• Avoid touching the dropper tip to any surface, including your eye, to prevent contamination.
• If you are using other eye medications, wait at least 5 minutes before applying the next medication.
• Do not wear contact lenses while using the drops unless advised by your doctor.
• Store the eye drops at room temperature, away from direct sunlight and moisture.