Cyclogest (400mg) 15 Pessaries

Cyclogest pessaries are used to treat premenstrual syndrome, and postpartum depression, and to assist women who are undergoing assisted reproductive treatment, such as IVF. Progesterone, the active component of Cyclogest pessaries, is necessary for the healthy operation of the reproductive system.

Progestins

Cyclogest pessaries are typically used for various medical conditions and situations. Here are some common uses:

• Assisted Reproductive Technologies (ART)

Cyclogest may help women undergoing in vitro fertilization (IVF) or other assisted reproductive technologies.

• Threatened Miscarriage

Cyclogest may be prescribed in cases of threatened miscarriage where there is a concern about inadequate progesterone levels.

• Hormone Replacement Therapy (HRT)

Postmenopausal women undergoing hormone replacement therapy may use cyclogest pessaries as part of their treatment.

• Endometrial Hyperplasia

Cyclogest may help in the treatment of endometrial hyperplasia, a condition characterized by the abnormal thickening of the lining of the uterus.

• Menstrual Irregularities

In some cases of irregular menstrual cycles or amenorrhea (absence of menstruation), cyclogest may induce a withdrawal bleed.

• Postnatal Depression

Cyclogest may help treat postpartum depression. The placenta produces progesterone during pregnancy, and postpartum depression may happen due to a decrease in progesterone levels following delivery.

Follow these dosage instructions:

• For IVF Treatment

The recommended dosage is 400mg dose of Cyclogest pessary per day, through vaginal insertion. Start using Cyclogest pessary on the day of egg retrieval.

• For Premenstrual Syndrome or Postnatal Depression Treatment

The recommended dosage is 200 mg or 400mg dose of Cyclogest pessary per day, through vaginal or rectal insertion.

If you think you have used too much of this medicine, talk to your doctor.

If you miss a dose, make sure to take it as soon as possible the same day. If you don't remember missing the dose, don't double it. Consult your doctor on how to adjust the missing doses.

Please follow these steps to use the Cyclogest Pessary:

• Before handling the pessary, wash your hands thoroughly to minimize the risk of infection.
• Many women find it easier to insert the pessary while lying down, either on their back with knees bent or in a side-lying position with one leg drawn up.
• Each pessary is individually wrapped. Carefully remove it from the packaging, being cautious not to damage the pessary.
• Gently insert the pessary into the vagina as far as is comfortable. It is designed to dissolve and release the medication slowly over time. You may use a clean applicator if one is provided, or you can insert it with a clean finger.
• After inserting the pessary, wash your hands again to ensure cleanliness.
• Some healthcare providers recommend lying down for a short period after inserting the pessary to allow it to stay in place and start to dissolve.
• Use the medication exactly as prescribed by your doctor. The dosage and frequency will depend on the specific reason for using Cyclogest.
• Continue using Cyclogest for the full duration prescribed by your doctor even if you start to feel better. Abruptly stopping the medication may not provide the intended benefits.

You should not use Cyclogest if you have:

• Known hypersensitivity to the active substances, soybean lecithin, peanut, or to any of the medicine component
• Known or Past or suspected breast cancer
• Known or suspected estrogen-dependent malignant tumors (e.g genital tract carcinoma)
• Undiagnosed genital bleeding
• Women with rare hereditary blood disorders called porphyrias
• Women with severe liver disease.

Side Effects of Cyclogest may include:

• Drowsiness
• Stomach upset or sugar-upset digestion
• Breast tenderness
• Hot Flashes
• Constipation/Diarrhoea
• Fatigue (when used in assisted conception)
• Disturbance of the menstrual cycle
• Increased mucus from the vagina or anus
• Vaginal pain
• Flatulence with the anorectal route

If you encounter any of the following symptoms while undergoing treatment, or even a few days after the last dosage, be cautious and notify your doctor right away:

• Discomfort in the chest or calves, an abrupt decrease in breath, or blood in the cough, all of which could be signs of clots in the heart, lungs, or legs
• Severe headache or vomiting, changes in speech or vision, dizziness, fainting, or weakness in one arm or leg suggesting a possible clot in the brain or eye
• A worsening of depression

Before using Cyclogest, talk to your doctor or chemist if you have or have ever had

• Liver issues, such as jaundice, or the yellowing of the skin and eye whites.
• Seizures/Epilepsy
• Migraine
• Respiratory illness (asthma)
• Renal or cardiac dysfunction
• Diabetes

Talk to your doctor if you are taking other medication as well. Cyclogets may interact with drugs like:

• CYP450-3A4 such as barbiturates
• Anti-epileptic agents (phenytoin, carbamazepine)
• Rifampicin
• Phenylbutazone
• Bromocriptine
• Spironolactone, griseofulvin
• Some antibiotics (ampicillin, tetracyclines)
• Ciclosporin
• Aminoglutethimide
• Coumarins
• Anti-diabetic drugs
• Diazepam
• Tizanidine
• Terbinafine

Store the medicine at a controlled room temperature. Keep the medication away from bright lights, moisture, and children.

No

Continue the use of Cyclogest for 38 days if the pregnancy has been confirmed. Talk to your doctor in detail.