Diabetron (80mg) 20 Tablets

Gliclazide, the active ingredient in the 80mg tablet, primarily acts by stimulating insulin release from pancreatic beta cells. It belongs to the sulfonylurea class of drugs and selectively binds to sulfonylurea receptors (SURs) on the beta cell membrane. This binding promotes the closure of ATP-sensitive potassium channels, leading to membrane depolarization and subsequent calcium influx. The increased intracellular calcium triggers insulin secretion, which helps lower blood glucose levels. Gliclazide's mechanism of action is specific to functioning beta cells, enhancing their response to glucose and improving glycemic control in individuals with type 2 diabetes.

Gliclazide 80mg

Sulfonylurea (anti-diabetic).

Tablet

The following are the uses of Gliclazide 80mg Tablet:

• Used for treating Type 2 diabetes by controlling blood sugar levels.
• Used to improve insulin sensitivity, helping cells use glucose more effectively.
• Used to stimulate insulin release from the pancreas, reducing blood sugar spikes.
• Used for managing long-term blood sugar control, especially in stable diabetes.
• Used as an alternative to other diabetes medications when dietary changes are insufficient.
• Used to prevent diabetes-related complications, such as kidney damage and nerve pain.
• Used in combination with lifestyle changes for comprehensive diabetes management.
• Used to potentially delay the progression of prediabetes to Type 2 diabetes.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Diabetes Type 2- Initially, 80mg daily (40mg in the morning and 40mg in the evening)
• Diabetes Type 2 (Elderly)- Initially, 40mg daily (20mg in the morning and 20mg in the evening)
• Diabetes Type 2 (Child)- Initially, 0.2mg/kg body weight daily in 1 or 2 doses

In the case of an overdose of Gliclazide 80mg Tablets, symptoms may include severe hypoglycemia, which can lead to dizziness, sweating, confusion, and even loss of consciousness. It is important to seek medical assistance immediately if an overdose is suspected. Prompt treatment can help stabilize blood sugar levels and manage any potential complications. Overdose severity may vary, so rapid response and medical intervention are vital to ensure the best possible outcome.

In the case of a missed dose of Gliclazide 80mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. If you miss multiple doses, consult your healthcare provider for guidance on how to safely resume your medication regimen. It is crucial to maintain a consistent medication routine for effective diabetes management.

To take Gliclazide 80mg Tablet, swallow the tablet whole with a glass of water, preferably in the morning before breakfast, following the dosage instructions provided by your healthcare professional, ensuring not to break, crush, or chew the tablet for optimal effectiveness.

Following are the conditions when Gliclazide 80mg Tablet should not be taken:

• Should not be used in individuals with a known allergy to Gliclazide or sulfonylurea medications.
• Contraindicated in patients with type 1 diabetes mellitus.
• Not suitable for individuals with diabetic ketoacidosis.
• Should not be used in patients with severe liver or kidney disease.
• Not recommended for individuals with a history of severe gastrointestinal problems or bowel obstruction.
• Contraindicated during pregnancy and breastfeeding.
• Should be avoided in patients with a known sensitivity to sulfonamides.

The side effects of Gliclazide 80mg Tablet may include:

• Hypoglycemia (low blood sugar)
• Nausea and vomiting
• Stomach pain or discomfort
• Diarrhea or constipation
• Skin rashes or itching
• Weight gain
• Blurred vision
• Allergic reactions (rare)

Following are the precautions and warnings for Gliclazide 80mg Tablet:

• Not recommended for individuals with a known allergy to Gliclazide or sulfonylurea drugs.
• Patients with liver or kidney problems should use with caution and under medical supervision.
• May cause hypoglycemia; monitor blood glucose levels regularly and be aware of symptoms.
• Avoid excessive alcohol consumption as it can increase the risk of hypoglycemia.
• Inform your doctor if you have a history of heart or blood vessel diseases before taking this medication.
• Elderly patients may be more susceptible to the hypoglycemic effects; dose adjustment might be necessary.
• Always carry glucose tablets or a sugary snack to treat hypoglycemia if it occurs.

Following are the drug interactions for Gliclazide 80mg Tablet:

• Alcohol consumption may increase the risk of hypoglycemia, and monitoring blood glucose levels is essential.
• Drugs affecting liver enzymes, such as rifampicin, can reduce the efficacy of Gliclazide.
• Beta-blockers may mask the symptoms of hypoglycemia, and caution is needed when used together.
• NSAIDs like ibuprofen can reduce the hypoglycemic effect of Gliclazide, requiring close monitoring.
• Corticosteroids may increase blood glucose levels, necessitating adjustments in Gliclazide dosage.
• Thiazide diuretics can elevate blood glucose, and careful monitoring is required during co-administration.
• Other antidiabetic medications may interact, potentially leading to additive hypoglycemic effects.

Following are the food interactions for Gliclazide 80mg Tablet:

• Alcohol consumption should be avoided or limited as it can affect blood sugar levels and may increase the risk of hypoglycemia.
• Grapefruit and grapefruit juice should be consumed with caution as they may alter the blood levels of Gliclazide, potentially leading to an increased risk of hypoglycemia.
• High-fiber foods like whole grains, legumes, and vegetables can slow down the absorption of Gliclazide, which may require dosage adjustments.
• Fatty meals can delay the absorption of Gliclazide, potentially affecting its effectiveness.
• Avoid excessive consumption of sugary foods and beverages as they can cause rapid spikes in blood sugar levels.
• Caffeine intake should be monitored as it can affect blood sugar levels and may interfere with the medication's action.
• A balanced diet with consistent carbohydrate intake is recommended to ensure stable blood sugar control while taking Gliclazide.
• Follow dietary guidelines provided by your healthcare professional to optimize the medication's effectiveness.

Gliclazide 80mg Tablets should be stored in a cool, dry area, preferably at room temperature, ensuring it remains below 25°C. Protect the tablets from light exposure by keeping them in their original packaging or a light-resistant container. It is crucial not to store the medication in the bathroom or kitchen, as heat and moisture can affect its potency. Always check the expiration date, and if the tablets have passed their expiry, do not use them and dispose of them safely. Proper disposal methods include returning the medication to a pharmacy or a designated medication disposal location, ensuring it is out of reach of children and pets. Never flush medications or throw them into the trash, as this can lead to environmental contamination.

Following are the quick tips for Gliclazide 80mg Tablet:

• Take the tablet as directed by your doctor, typically once or twice daily with or after meals.
• Swallow the tablet whole without crushing or chewing for optimal absorption.
• Maintain a consistent daily routine for taking the medication.
• Regularly monitor your blood sugar levels as advised by your healthcare provider.
• Inform your doctor about any other medications you are taking to avoid potential interactions.
• Do not stop taking the medication without consulting your doctor, even if you feel better.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.

Glyclazide is a medication used to treat type 2 diabetes, and its dosage is tailored to each patient's response and blood sugar levels. To achieve the best results and identify any issues that may require attention, it is essential to monitor your blood sugar levels and undergo regular laboratory tests while taking this medication. These tests allow your healthcare provider to assess how well the medication is working and ensure it is safe for you to take. They also help detect any complications arising from the condition or the medication itself. Specifically, there are several tests that you should undergo to assess your overall health and monitor for complications: