Emergency Pills (0.75mg) 2 Tablets

Levonorgestrel is a synthetic progestin that primarily works by inhibiting ovulation. Its mechanism of action involves suppressing the release of gonadotropins, specifically luteinizing hormone (LH), which is essential for ovulation. By inhibiting the mid-cycle surge of LH, levonorgestrel effectively prevents the release of a mature egg from the ovary. This action is achieved through its binding to progesterone receptors in the brain, particularly in the hypothalamus and pituitary gland, leading to a disruption in the normal hormonal feedback system that regulates ovulation. Additionally, levonorgestrel can alter the cervical mucus, making it less permeable to sperm, and it may also affect the endometrium, potentially impairing implantation if fertilization does occur.

Levonorgestrel

Progestin contraceptive.

Tablet

The following are the uses of Levonorgestrel Tablet:

• Used for emergency contraception, providing a backup option to prevent pregnancy after unprotected intercourse.
• Used for regular contraception in the form of a daily pill, offering an effective birth control method.
• Used for treating irregular menstrual cycles, helping to regulate and normalize periods.
• Used for managing heavy menstrual bleeding, reducing excessive blood loss during periods.
• Used for endometriosis treatment, alleviating pain and managing the condition's symptoms.
• Used for certain types of uterine disorders, providing therapeutic benefits.
• Used for preventing pregnancy after contraceptive failure, ensuring additional protection.

Take one tablet at a time. The medication works best if taken within 72 hours of having unprotected intercourse. Take your first dose immediately after intercourse and the second dose 12 hours later. Women who weigh more than 70kgs may need to take 2 tablets at a time for better results.

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In the case of an overdose of Levonorgestrel tablets, it is important to remain calm and seek medical advice promptly. Common symptoms of an overdose may include nausea, vomiting, dizziness, and abdominal pain. The severity of symptoms can vary, and in some cases, it may lead to an irregular menstrual cycle or breakthrough bleeding. If you suspect an overdose, contact a healthcare professional or poison control center for guidance on the appropriate next steps.

In the case of a missed dose of Levonorgestrel Tablet, it is important to take the missed dose as soon as possible. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. However, if you regularly miss doses, it is recommended to use a backup method of contraception, such as condoms, until you have taken the medication consistently for at least seven days. Always consult your healthcare provider if you have any concerns or questions about missed doses.

To take Levonorgestrel Tablet, place the tablet under your tongue or between your cheek and gum and let it dissolve completely without chewing or swallowing it, ensuring it is taken as directed by your healthcare provider or as indicated on the product packaging.

Following are the conditions or circumstances when Levonorgestrel Tablet should not be taken:

• Allergic reaction If you have a known allergy to Levonorgestrel or any other progestin hormones, or if you've experienced severe allergic reactions to contraceptive pills in the past.
• Pregnancy Levonorgestrel Tablet is not for use in pregnant women as it is a contraceptive emergency method.
• Breastfeeding It is not recommended for breastfeeding mothers as it may pass into breast milk and affect the nursing infant.
• Undiagnosed abnormal genital bleeding Should not be used if there is unexplained, irregular, or persistent bleeding from the vagina.
• Liver disease Contraindicated in individuals with severe liver diseases or liver tumors.
• History of blood clots Should not be used in patients with a history of deep vein thrombosis, pulmonary embolism, or other thromboembolic disorders.
• Stroke or heart attack Not suitable for individuals who have had a stroke or heart attack in the past.
• Severe hypertension Should be avoided in patients with uncontrolled high blood pressure.
• Diabetes complications Not recommended for those with diabetes-related complications affecting the eyes, kidneys, or blood vessels.
• Migraine headaches Should be used with caution in individuals with severe or frequent migraine headaches, especially if accompanied by aura.

The side effects of Levonorgestrel Tablet may include:

• Nausea and vomiting
• Abdominal pain or cramps
• Dizziness or lightheadedness
• Fatigue and weakness
• Headaches
• Breast tenderness
• Irregular menstrual bleeding
• Mood changes and increased anxiety

Following are the precautions and warnings for Levonorgestrel Tablet:

• Not recommended for individuals with a known allergy or hypersensitivity to Levonorgestrel or any of the tablet's components.
• Women with a history of blood clots, stroke, or heart attack should use with caution and under medical supervision, as it may increase the risk of these conditions.
• Those with liver disease or liver function impairment should exercise caution and seek medical advice before use, as it may affect liver function.
• If you have diabetes, be cautious as it may affect blood sugar levels and require adjustments in diabetes management.
• Levonorgestrel may impact bone mineral density with long-term use; regular monitoring is advised.
• This medication does not protect against sexually transmitted infections (STIs); use barrier methods for STI prevention.
• Not recommended for women with undiagnosed abnormal vaginal bleeding; consult a healthcare professional for evaluation.

Following are the drug interactions for Levonorgestrel Tablet:

• Co-administration with CYP3A4 inducers (e.g., rifampin, St. John's Wort) may reduce the effectiveness of Levonorgestrel, potentially leading to contraceptive failure.
• Using Levonorgestrel with CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) can increase its blood levels, potentially leading to increased side effects.
• Antiepileptic medications like carbamazepine, phenytoin, and barbiturates may reduce the effectiveness of Levonorgestrel, necessitating the use of backup contraception.
• Levonorgestrel may interact with other hormonal contraceptives, potentially affecting hormone levels and contraceptive efficacy.
• It can interact with certain antibiotics (e.g., rifampin, rifabutin) and antifungals (e.g., griseofulvin), which may reduce its effectiveness.
• The effectiveness of Levonorgestrel may be reduced when taken with HIV protease inhibitors (e.g., ritonavir, lopinavir/ritonavir) and non-nucleoside reverse transcriptase inhibitors (NNRTIs).
• Caution is advised when using Levonorgestrel with herbal products like St. John's Wort, as it may decrease hormone levels and reduce contraceptive efficacy.

Following are the food interactions for Levonorgestrel Tablet:

• Avoid consuming ethanol (alcohol) as it may increase the risk of side effects like nausea, dizziness, and drowsiness.
• Grapefruit and grapefruit juice should be consumed with caution as they can affect the metabolism of the drug, potentially leading to increased levels of Levonorgestrel in the body.
• High-fat meals may slightly delay the absorption of Levonorgestrel, but this is not considered a significant interaction.
• Avoid St. John's Wort as it can reduce the effectiveness of Levonorgestrel by increasing its breakdown.
• Do not consume herbal teas containing St. John's Wort while taking this medication.
• Avoid excessive caffeine intake as it may interact with Levonorgestrel, potentially affecting the liver's ability to metabolize the drug.
• Be cautious with vitamin C supplements, as high doses may interfere with the absorption of Levonorgestrel.
• Consult your healthcare provider for specific dietary recommendations and adjustments while taking Levonorgestrel Tablets.

Levonorgestrel Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or designated storage area, at room temperature (between 68°F and 77°F). It is crucial to keep the tablets in their original packaging or container, ensuring they remain protected from light, moisture, and humidity. Avoid storing them in the bathroom or kitchen, as these areas can expose the medication to heat and moisture. Always check the expiration date, and do not use the tablets if they have expired. When disposing of unused or expired tablets, do not flush them down the toilet or throw them into the trash. Instead, follow local guidelines for pharmaceutical waste disposal or consult a pharmacist for advice on safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption, as it is essential for their safety.

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Following are the quick tips for Levonorgestrel Tablet:

• Levonorgestrel is a hormone-based emergency contraceptive, not a regular birth control method.
• Take the tablet as soon as possible within 72 hours of unprotected sex.
• One tablet is typically taken as a single dose.
• It may cause nausea; take it with food or milk to reduce this side effect.
• Inform your doctor if you have any medical conditions or are taking other medications.
• Levonorgestrel does not protect against sexually transmitted infections.
• This medication is not recommended for regular use; consider a more suitable contraceptive method.
• Store the tablets at room temperature, away from light and moisture.