Exelon (3mg) 28 Capsules

Exelon (3mg) 28 Capsules

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  • Manufacturer NOVARTIS PHARMACEUTICALS (PVT.) LTD.
  • Generic Name Rivastigmine

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Rivastigmine 3mg capsules work by inhibiting acetylcholinesterase and butyrylcholinesterase, two enzymes responsible for breaking down acetylcholine in the brain. By blocking these enzymes, rivastigmine increases the levels of acetylcholine, a neurotransmitter involved in memory, cognition, and nerve signaling. This increase in acetylcholine helps improve cognitive function and slows down the progression of symptoms in conditions like Alzheimer's disease and Parkinson's disease dementia. The mechanism of action specifically targets the cholinergic system, which plays a crucial role in learning, memory, and attention.

  • Ingredients

    Rivastigmine
  • Drug Class

    Cholinesterase inhibitor.

  • Dosage Form

    Capsule

  • Uses

    The following are the uses of Rivastigmine 3mg Capsule:

    • Used for treating mild to moderate Alzheimer's disease.
    • Used to improve cognitive function and memory.
    • Used to enhance attention and concentration in patients with dementia.
    • Used to slow down the progression of symptoms.
    • Used for managing symptoms of Parkinson's disease dementia.
    • Used to reduce agitation and improve daily functioning.
    • Used to enhance overall quality of life for dementia patients.
  • In case of Overdose

    In the case of an overdose of Rivastigmine 3mg Capsules, it is important to remain calm and take swift action. Contact a healthcare professional or poison control center immediately for guidance. They will provide specific instructions based on the severity of the overdose. Symptoms may include nausea, vomiting, dizziness, and in severe cases, seizures or difficulty breathing. Quick response and appropriate medical care are vital to managing the situation effectively and ensuring the individual's well-being.

  • Missed Dose

    In the case of a missed dose of Rivastigmine 3mg Capsule, it is recommended to take the medication as soon as you remember, provided there is a reasonable interval before the next scheduled dose. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. It is important to maintain a consistent medication routine, but if you frequently miss doses, inform your healthcare professional, who can advise on the best course of action.

  • How To Use

    To take Rivastigmine 3mg capsules, swallow the capsule whole with a full glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, without crushing or chewing the capsule.

  • When Not to Use

    Following are the conditions/situations when Rivastigmine 3mg Capsule should not be used:

    • Should not be used in individuals with a known allergy to Rivastigmine or other similar medications.
    • Contraindicated in patients with severe liver or kidney disease.
    • Not suitable for individuals with certain types of heart problems, such as bradycardia (slow heart rate) or sick sinus syndrome.
    • Should not be used in patients with active stomach ulcers or gastrointestinal bleeding.
    • Contraindicated in patients with a history of seizures or conditions that lower the seizure threshold.
    • Not recommended for individuals with severe lung diseases like asthma or chronic obstructive pulmonary disease (COPD).
    • Should be avoided in patients with urinary obstruction or difficulty urinating.
    • Not suitable for individuals with a history of severe adverse reactions to cholinesterase inhibitors.
  • Side Effects

    The side effects of Rivastigmine 3mg Capsule may include:

    • Nausea and vomiting
    • Diarrhea
    • Abdominal pain
    • Loss of appetite
    • Weight loss
    • Dizziness and headache
    • Fatigue and sleep disturbances
  • Precautions & Warnings

    Following are the precautions and warnings for Rivastigmine 3mg Capsule:

    • Not recommended for individuals with a known hypersensitivity or allergy to Rivastigmine or other similar medications.
    • Patients with a history of gastrointestinal disorders should exercise caution as this medication can aggravate these conditions.
    • May cause dizziness or drowsiness; patients should avoid driving or operating heavy machinery until they know how the medication affects them.
    • Individuals with heart conditions, especially bradycardia or sick sinus syndrome, should be closely monitored while on this medication.
    • Caution is advised in patients with a history of seizures or epilepsy, as Rivastigmine may lower the seizure threshold.
    • Not recommended for use in children and adolescents under 18 years of age due to insufficient data on safety and efficacy.
    • Pregnant and breastfeeding women should consult their doctor before taking Rivastigmine, as the risks and benefits should be carefully considered.
  • Drug Interactions

    Following are the drug interactions for Rivastigmine 3mg Capsule:

    • Anticholinergic medications (e.g., tricyclic antidepressants, antihistamines) may counteract the effects of Rivastigmine and should be avoided.
    • Rivastigmine can increase the cholinergic effects of Succinylcholine, potentially leading to prolonged muscle paralysis.
    • Concurrent use with Metoclopramide may increase the risk of extrapyramidal symptoms.
    • Rivastigmine may increase the effects of cholinergic agonists, such as Pyridostigmine, causing excessive cholinergic stimulation.
    • Close monitoring is required when used with beta-blockers, as Rivastigmine may mask the symptoms of hypoglycemia.
    • Drugs that inhibit or induce the CYP450 enzyme system can affect Rivastigmine metabolism, potentially requiring dosage adjustments.
    • Caution is advised when combining Rivastigmine with other centrally acting medications, as it may enhance their effects.
  • Food Interactions

    Following are the food interactions for Rivastigmine 3mg Capsule:

    • Avoid consuming large amounts of fatty or high-fat meals while taking this medication, as it may affect the absorption and distribution of the drug.
    • Grapefruit and grapefruit juice should be consumed with caution, as they can inhibit certain enzymes and potentially increase the concentration of Rivastigmine in the blood, leading to more side effects.
    • Alcohol may increase the risk of gastrointestinal side effects like nausea and vomiting, so it's best to limit or avoid alcohol consumption.
    • Avoid taking this medication with a heavy meal, as it may slow down the absorption process.
    • A balanced diet with a variety of fruits, vegetables, whole grains, and lean proteins is generally recommended to support overall health while taking this medication.
    • Stay well-hydrated by drinking enough water throughout the day, especially if experiencing increased sweating as a side effect.
    • Avoid excessive caffeine intake, as it may interact with the medication and exacerbate side effects like nervousness and insomnia.
  • Storage/Disposal

    Rivastigmine 3mg capsules should be stored in a cool, dry place, preferably at room temperature, between 68°F and 77°F (20°C and 25°C). Protect the capsules from excessive heat, moisture, and direct sunlight, as these conditions can degrade the medication. Keep the container tightly sealed to maintain its integrity and prevent exposure to air and humidity. Always check the expiration date, and do not use the capsules if they have passed their expiry date. When disposing of unused or expired capsules, do not throw them into the trash or flush them down the toilet. Instead, follow local guidelines or consult a pharmacist for safe disposal options to minimize environmental impact. Keep the medication securely stored and out of the reach of children and pets to prevent accidental consumption.

  • Quick Tips, if any

    Following are the quick tips for Rivastigmine 3mg Capsule:

    • Take the capsule as directed by your doctor, usually once or twice daily.
    • Swallow the capsule whole with a full glass of water; do not crush or chew.
    • It can be taken with or without food but take it consistently with regards to meals.
    • Start with a lower dose and gradually increase as advised by your doctor.
    • Do not abruptly stop taking it; consult your doctor for a proper tapering plan.
    • Regularly monitor your health and report any unusual symptoms to your doctor.
    • Store in a cool, dry place, away from direct sunlight and moisture.

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