Eyemox-D (0.5/0.1%) Eye Drops

Dexamethasone, a potent synthetic corticosteroid, primarily reduces inflammation by suppressing various cells involved in the immune response. It inhibits the release of inflammatory mediators, such as prostaglandins and leukotrienes, and decreases capillary permeability, thereby reducing swelling and inflammation in the eye. Moxifloxacin, a fluoroquinolone antibiotic, exerts its action by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes crucial for bacterial DNA replication and transcription. This inhibition leads to the disruption of bacterial DNA synthesis, preventing the replication and spread of the bacteria responsible for ocular infections.

Dexamethasone, Moxifloxacin

Corticosteroid, Fluoroquinolone.

Drop

The following are the uses of Dexamethasone, Moxifloxacin Drop:

• Used for reducing inflammation and suppressing the immune system in various eye conditions.
• Used for treating bacterial infections in the eye, including conjunctivitis and corneal ulcers.
• Used for alleviating eye redness, itching, and discomfort caused by allergies.
• Used for managing post-operative eye inflammation and preventing infection after eye surgeries.
• Used for treating uveitis, an inflammation of the middle layer of the eye.
• Used for relieving dry eye symptoms and promoting eye lubrication.
• Used for preventing and treating eye infections in patients with compromised immune systems.
• Used for reducing the risk of eye complications in certain systemic conditions.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Moxifloxacin 0.5%-
• Adults- one drop in the affected eye(s) every 12 hours for 7 days.
• Pediatric patients aged 1 year and above- one drop in the affected eye(s) every 12 hours for 5 days.
• Avoid contact lenses during usage to prevent eye irritation.
• Dexamethasone 0.1%-
• Adults- one drop in the affected eye(s) every 12 hours for up to 4 days.
• Pediatric patients- Dosage based on body weight and medical discretion. Not recommended for children below 2 years of age.
• Avoid using for more than 4 days to prevent worsening eye pressure in glaucoma patients.

In the case of an overdose of Dexamethasone, symptoms may include an increase in existing side effects such as weight gain, fluid retention, and mood changes. Moxifloxacin Drops overdose can lead to more severe reactions, including seizures, cardiac arrhythmias, and severe allergic reactions. If either medication is ingested in excess, immediate medical care is necessary to manage potential complications and ensure patient safety.

In the case of a missed dose of Dexamethasone, it is recommended to take the medication as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. For Moxifloxacin eye drops, if you miss a dose, apply the drops as soon as possible. If it's almost time for your next dose, you may skip the missed dose and continue with your regular dosing schedule. It is important not to overuse the drops to compensate for a missed application.

To use Dexamethasone and Moxifloxacin eye drops, wash your hands, tilt your head back, gently pull down your lower eyelid, hold the dropper above the eye, and squeeze the prescribed number of drops into the eye, then close your eyes gently to allow the drops to absorb.

Here are the conditions or situations when Dexamethasone, Moxifloxacin eye drops should not be used:

• Avoid using these eye drops if you have a known allergy to Dexamethasone, Moxifloxacin, or any other similar antibiotics.
• Not suitable for individuals with a history of hypersensitivity or severe reactions to any ingredients in the eye drop formulation.
• Do not use if you have a current or recent fungal, viral, or mycobacterial infection in the eye(s).
• Contraindicated for individuals with a history of glaucoma or increased intraocular pressure (IOP).
• Not recommended for patients with untreated or uncontrolled bacterial, fungal, or viral infections in the body.
• Avoid using these eye drops if you have a corneal ulcer or a history of corneal problems.
• Do not use if you have a history of ocular herpes simplex virus (HSV) infection or any active HSV infection.

The side effects of Dexamethasone, Moxifloxacin Eye Drops may include:

• Eye irritation or itching
• Burning or stinging sensation in the eyes
• Redness or swelling of the eyelids
• Blurred vision or changes in eyesight
• Eye discharge or crusting
• Increased sensitivity to light (photophobia)
• Allergic reactions, such as rash, itching, or swelling around the eyes

Following are the precautions and warnings for Dexamethasone, Moxifloxacin Eye Drops:

• Do not use these eye drops if you are allergic to any of their ingredients, including dexamethasone or moxifloxacin.
• If you have a history of eye infections, inform your doctor before using these drops, as they may not be suitable.
• Contact lens wearers should remove lenses before instilling the drops and wait at least 15 minutes after administration before reinserting them.
• These eye drops are for external use only; do not swallow or inject.
• Avoid touching the dropper tip to any surface, including the eye or fingers, to prevent contamination.
• If you are using other eye medications, apply them at least 5 minutes before or after using Dexamethasone, Moxifloxacin drops to prevent drug interactions.
• Prolonged use of corticosteroid eye drops may lead to increased intraocular pressure and glaucoma; regular eye pressure checks are recommended.
• Consult your doctor if you have a history of eye surgery or any ongoing eye conditions before using these drops.

Following are the drug interactions for Dexamethasone and Moxifloxacin Drops:

• Dexamethasone can increase the risk of bleeding when taken with anticoagulants like warfarin, requiring close monitoring of coagulation levels.
• It may decrease the effectiveness of anti-diabetic medications, necessitating careful glucose monitoring.
• Dexamethasone can increase the risk of arrhythmias when used with certain heart medications, such as digoxin.
• Moxifloxacin drops may enhance the effects of other systemic or topical fluoroquinolones, increasing the risk of adverse reactions.
• The effectiveness of live attenuated vaccines may be reduced when administered concurrently with moxifloxacin.
• Concurrent use with other otic medications may result in additive side effects or altered therapeutic outcomes.
• Drugs known to prolong the QT interval should be used cautiously with moxifloxacin due to potential cardiac risks.

Following are the food interactions for Dexamethasone and Moxifloxacin Drops:

• Avoid high-sodium foods, as Dexamethasone can cause sodium retention, leading to increased blood pressure.
• Maintain a balanced diet to prevent stomach irritation and ensure proper nutrition, especially with long-term use.
• Avoid excessive alcohol consumption, as it may increase the risk of gastrointestinal bleeding when combined with Moxifloxacin.
• Grapefruit and grapefruit juice should be avoided as they can interfere with the metabolism of Moxifloxacin, potentially increasing its levels in the body.
• Consume calcium-rich foods like dairy products, leafy greens, and fortified foods to support bone health, as Moxifloxacin may affect calcium absorption.
• Avoid caffeine-rich foods and beverages as they can increase the risk of caffeine-related side effects, especially when used with Dexamethasone.
• Stay hydrated by drinking plenty of water to prevent dehydration, which can be a concern with Moxifloxacin use.
• No specific food restrictions are associated with Moxifloxacin Drops, but maintaining a healthy diet is generally recommended.

Dexamethasone and Moxifloxacin eye drops should be stored in a cool, dry place, preferably between 68°F and 77°F (20°C and 25°C). Keep the bottle tightly closed when not in use to prevent contamination. It is crucial to maintain the integrity of the medication by protecting it from direct sunlight, heat, and moisture. Always check the expiration date before using the drops, and never use them if they have expired. Dispose of any unused or expired medication responsibly; do not pour it down the drain or flush it down the toilet. Contact your pharmacist or healthcare provider for guidance on proper disposal methods. Keep the eye drops out of the reach of children and pets to prevent accidental exposure or ingestion.

Following are the quick tips for Dexamethasone and Moxifloxacin Drops:

• Wash your hands thoroughly before administering the eye drops to maintain hygiene.
• Tilt your head back, gently pull down your lower eyelid, and instill the prescribed number of drops into the eye.
• Close your eyes gently and apply light pressure to the inner corner of the eye for a few seconds to prevent drainage.
• Avoid touching the dropper tip to any surface, including your eye, to prevent contamination.
• If using other eye medications, wait at least 5 minutes before applying the next medication to ensure proper absorption.
• Do not wear contact lenses while using these drops unless advised by your doctor.
• Store the eye drops at room temperature, away from direct sunlight and moisture.

While on medication Moxifloxacin 0.5% and Dexamethasone 0.1%, it is essential to monitor your health for your safety. This is especially important due to the possible side effects of these medications, which can affect your blood, kidneys, hearing and vision. Here are a few lab tests you may need to perform • Firstly, blood tests are required to monitor your blood cells, especially your red blood cells, white blood cells and platelets. This is important as these medications can cause neutropenia, which is associated with low levels of white blood cells, especially neutrophils. Secondly, regular kidney function tests are essential as Moxifloxacin can cause kidney damage. These tests may include serum creatinine and blood urea nitrogen (BUN) measurements. Due to the potential side effect of permanent hearing loss with dexamethasone, hearing tests are recommended, especially if you are on this medication for an extended period. Vision tests are recommended as dexamethasone can rarely cause optic nerve problems leading to glaucoma and vision loss, especially in adults who have taken high doses for multiple days. It is advisable to consult with your healthcare provider to determine which specific lab tests you require and how often they should be performed. In summary, monitoring your health through regular appropriate lab tests is essential to ensure any potential side effects are caught early and treatment plans can be adjusted if necessary.