Feldene (10mg) 40 Capsules

Piroxicam, a nonsteroidal anti-inflammatory drug (NSAID), exerts its mechanism of action by inhibiting cyclooxygenase (COX) enzymes, primarily COX-1 and COX-2. These enzymes play a crucial role in the synthesis of prostaglandins, which are involved in mediating pain, inflammation, and fever. By blocking the action of COX enzymes, piroxicam reduces the production of prostaglandins, leading to decreased inflammation, pain relief, and reduction of fever. This inhibition of prostaglandin synthesis is the primary mode of action through which piroxicam achieves its therapeutic effects.

NSAID (Non-steroidal anti-inflammatory drug)

Capsule

The following are the uses of Piroxicam 10mg Capsule:

• Used for relieving inflammation and pain associated with arthritis.
• Used to reduce acute pain and inflammation post-surgery or injury.
• Used in the management of rheumatoid arthritis and osteoarthritis.
• Effective for treating migraine headaches and relieving menstrual pain.
• Used to reduce fever and discomfort in conditions like gout.
• Provides relief from dental pain and inflammation.
• Helps alleviate symptoms of ankylosing spondylitis.

Dose may be determined by the doctor. Adjustment may be required for people with renal and hepatic insufficiency

In the case of an overdose of Piroxicam 10mg Capsules, prompt medical attention is necessary. Symptoms of an overdose may include severe stomach pain, nausea, vomiting, and in extreme cases, seizures or loss of consciousness. If you suspect an overdose, seek medical help immediately and provide healthcare professionals with information about the medication and the amount ingested. Quick action can help mitigate potential health risks associated with excessive medication intake.

In the case of a missed dose of Piroxicam 10mg Capsule, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss several doses, consult your healthcare professional for advice on how to safely resume your medication and maintain its effectiveness. It is recommended to set reminders or use a pill organizer to help you remember to take your medication as prescribed.

To take Piroxicam 10mg Capsule, swallow the capsule whole with a full glass of water, preferably with food or after meals, once or twice a day as directed by your doctor.

Following are the conditions/situations when Piroxicam 10mg Capsule should not be taken:

• Should not be used in individuals with a known allergy to Piroxicam or other non-steroidal anti-inflammatory drugs (NSAIDs).
• Contraindicated in patients with active or recent gastrointestinal bleeding.
• Not suitable for individuals who have recently undergone coronary artery bypass graft (CABG) surgery.
• Should not be used in patients with severe heart failure or severe kidney disease.
• Contraindicated in pregnant women, especially during the third trimester.
• Not recommended for breastfeeding mothers.
• Should be avoided in individuals with a history of asthma or allergic reactions triggered by Aspirin or other NSAIDs.
• Not suitable for patients with active peptic ulcers or a history of recurrent peptic ulcers/bleeding.
• Should not be used in individuals with severe liver impairment.
• Contraindicated in patients with rare hereditary problems of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption.

The side effects of Piroxicam 10mg Capsule may include:

• Stomach pain or discomfort
• Nausea and vomiting
• Diarrhea
• Dizziness or lightheadedness
• Headache
• Skin rash or itching
• Increased blood pressure
• Fatigue

Following are the precautions and warnings for Piroxicam 10mg Capsule:

• Not recommended for individuals with known allergies to Piroxicam or other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
• Patients with a history of gastrointestinal bleeding, ulcers, or other gastrointestinal disorders should use with caution and under medical supervision.
• Kidney function should be monitored regularly, especially in elderly patients and those with pre-existing kidney issues.
• May increase the risk of cardiovascular events such as heart attack or stroke, especially with long-term use.
• Avoid using this medication if you have a history of heart disease, high blood pressure, or related conditions.
• Not suitable for pregnant women, especially during the third trimester, due to potential harm to the fetus.
• Breastfeeding women should consult a healthcare professional before using this medication as it may pass into breast milk.
• Always inform your doctor about all medications you are currently taking to avoid potential drug interactions.

Following are the drug interactions for Piroxicam 10mg Capsule:

• Aspirin and other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) may increase the risk of gastrointestinal bleeding or kidney problems when taken with Piroxicam.
• Lithium levels can be increased by Piroxicam, leading to potential toxicity.
• Anticoagulants like Warfarin may have their effects enhanced, requiring close monitoring.
• Diuretics and ACE inhibitors might reduce the elimination of Piroxicam, leading to increased drug levels.
• Piroxicam may decrease the efficacy of antihypertensive medications.
• Methotrexate toxicity can be increased due to Piroxicam's impact on renal function.
• The risk of adverse effects may be elevated when combined with other drugs that have similar side effects.

Following are the food interactions for Piroxicam 10mg Capsule:

• Avoid excessive alcohol consumption while taking Piroxicam as it may increase the risk of gastrointestinal bleeding and liver toxicity.
• Grapefruit and grapefruit juice should be consumed with caution as they can affect the metabolism of Piroxicam, potentially increasing its levels in the body and the risk of side effects.
• Avoid high-sodium foods and processed foods, as Piroxicam can cause sodium and water retention, which may worsen hypertension.
• Limit the intake of foods rich in vitamin K (like leafy greens) as Piroxicam may interfere with blood clotting.
• Avoid herbal supplements like Ginkgo Biloba and St. John's Wort, as they may increase the risk of bleeding.
• Consume calcium-rich foods or supplements as Piroxicam may affect bone mineral density over time.
• Avoid caffeine or reduce intake as it may increase the risk of gastrointestinal irritation.
• Follow a balanced diet, as Piroxicam may cause fluid retention and weight gain in some individuals.

Piroxicam 10mg capsules should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. It is crucial to keep the capsules in their original container, tightly sealed, to maintain their integrity and prevent contamination. Avoid exposing the medication to extreme temperatures, such as storing it in the bathroom or near heat sources like stoves or radiators. Regularly check the expiration date, and properly dispose of any unused or expired capsules. Do not dispose of them via flushing or pouring into drains; consult a pharmacist or healthcare professional for appropriate disposal methods. Additionally, keep the medication out of children's reach to prevent accidental consumption.

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Following are the quick tips for Piroxicam 10mg Capsule:

• Consult your doctor before use, especially if you have a history of stomach ulcers or kidney problems.
• Swallow the capsule whole with a full glass of water; do not crush or chew.
• Take the capsule with food or after meals to minimize stomach irritation.
• Avoid alcohol consumption while taking this medication as it may increase the risk of stomach bleeding.
• If you experience dizziness, avoid driving or operating heavy machinery.
• Inform your doctor about all medications you are taking to prevent potential drug interactions.
• Store the capsules in a cool, dry place, away from direct sunlight and moisture.