Fudic (2%) 15g Cream

Fusidic acid is a topical ointment that is used to treat skin infections caused by bacteria such as Staphylococcus aureus, Streptococcus pyogenes, and Escherichia coli. It works by interfering with the bacterial replication process. It derives from the fatty acid and amino acid lysine. As a lipophilic molecule, it is drawn to the lipid layers in biological membranes, making it potent in inhibiting bacterial protein synthesis. It enters the bacterial cell wall and disrupts the assembly of the ribosome, leading to the inhibition of peptidyl transferase. At physiological pH values, fusidic acid predominantly exists in its dissociated form, which works to inhibit the growth and replication of bacteria by binding to the entrainment factor EF-G subunit of bacterial ribosomes, which in turn prevents the synthesis of cell wall proteins. This mechanism of action makes fusidic acid a bacteriostatic agent, as it prevents the growth and reproduction of bacteria.

Fusidic Acid

Fusidane Class (Steroidal Antibiotic)

Cream

Fusidic Acid is utilized for the following therapeutic indications:

• Treating bacterial infections, particularly those caused by Staphylococcus aureus
• Addressing skin infections
• Managing eye infections caused by susceptible organisms

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Athlete's foot- Apply cream or powder forms of fusidic acid once or twice a day for up to four weeks.
• Scalp or fingernails fungal infection- Use the cream or lotion for several weeks as prescribed by your doctor.
• Jock itch- Apply cream or powder form of fusidic acid once or twice a day for up to four weeks.
• Pityriasis versicolor- Apply cream or lotion once a day for one to two weeks as prescribed by your doctor.
• Ringworm- Apply cream or powder form of fusidic acid once or twice a day for up to four weeks.
• Dosage for children depends on age and weight. Consult a doctor before giving medication to children.
• For the cream or lotion forms- Apply a thin layer to the affected area and surrounding skin. Spread evenly and thoroughly.
• For the powder form- Sprinkle the powder on the affected area and rub it in gently. Dust the area with talcum powder if you find the powder irritating or if it leaves a greasy residue.

Fusidic acid is a medication that helps treat certain infections. It is important to note that an overdose of this medication may result in adverse effects such as nausea, vomiting, and diarrhea. In more severe cases, or if the overdose is prolonged, patients may experience arrhythmias, jaundice, and joint pain. If an overdose occurs, it is vital to seek proper treatment immediately. This treatment may include rituals such as gastric lavage, administration of absorbents, antacids, and fluid resuscitation. It is crucial to monitor vital signs and consult a healthcare professional for guidance. Fortunately, if treatment is addressed promptly, a full recovery is likely. However, it is essential to consult a physician for specific treatment instructions as this information is not a substitute for professional medical advice.

If you have missed a dose of fusidic acid, it is important to take the missed dose as soon as possible unless it is almost time for the next scheduled dose. If you are unsure if you should take the missed dose or if it is almost time for the next scheduled dose, consult with your doctor or pharmacist. They will provide you with specific guidance regarding your missed dose to ensure your treatment plan remains effective. It is important to note that you should not take a double dose to make up for the missed dose as this can result in an overdose or adverse effects.

Fusidic acid is available as both an oral and topical medication, and it's essential to follow the specific instructions provided with your medication for correct usage. For oral fusidic acid, it is crucial to read any information leaflet and warning labels that come with the medication. If you have any queries, consult your doctor or pharmacist. Take the medication as directed by your physician, with the typical adult dose being one 500 mg tablet every 12 hours. Ensure you take it with a meal to avoid an upset stomach. Swallow the tablet whole with water and follow the dosing schedule provided. Do not alter the dosage or duration of treatment without your doctor's advice. For topical fusidic acid, wash your hands thoroughly before and after applying the medication to prevent spreading it to other areas. Clean and dry the affected area before applying a thin layer of the cream, ointment, or lotion as directed. Avoid contact with your eyes, nose, or mouth, and rinse immediately if contact occurs. Use the medication regularly as directed, even if symptoms improve, to ensure the best results. If over-the-counter formulations are used, follow the instructions on the label carefully. It is important to note that if you experience severe irritation, burning, or any other unpleasant reaction, discontinue the use of the medication and consult with your doctor. Consulting with a healthcare professional is essential to ensure proper usage and minimize the chances of adverse effects. Remember, always read and follow the specific instructions provided with your medication as these may vary depending on the formulation and your medical condition.

Discerning instances where this medication may not be appropriate:

• You are allergic to fusidic acid, or any of the other ingredients in the medication.
• You have diarrhea, vomiting, or nausea.
• You have a serious kidney disease.
• You have a serious infection that needs to be addressed by a medical professional.

Unraveling the side effects lurking behind this medications are as follows:

• Skin Irritation

• Burning or Stinging Sensation

• Gastrointestinal Issues (Systemic Form)

• Allergic Reactions (Systemic Form)

Fusicoccin, a peptide derived from Fusidium coccineum, is being investigated for its potential to inhibit the adhesion of vancomycin-resistant enterococci to epithelial cells. Fusidic acid, the acid that fusicoccin is derived from, is in turn derived from the fungus Fusidium coccineum and is commonly used to treat Staphylococcus aureus and Staphylococcus epidermis skin infections as well as for the prophylaxis of recurrences of these infections. It is soluble in methanol and ethanol, and slightly soluble in water, but very poorly soluble in hexane. Fusidic acid can be stored at room temperature and is available in both powder and liquid forms to be administered by clinicians and professionals with expertise in prescribing such drugs.