Glusimet (50/850mg) 14 Tablets

Sitagliptin is a drug used to treat patients with type 2 diabetes. It works by blocking the breakdown of incretins, which are hormones that help stimulate insulin production in response to rising blood glucose levels. By enhancing incretin levels, Sitagliptin helps to increase insulin secretion and reduce blood sugar levels. Additionally, Sitagliptin also slows down the rate at which food moves from the stomach to the intestine, helping to keep you full for longer and potentially leading to weight loss. Metformin is another common medication used to treat type 2 diabetes. It works primarily by inhibiting the production of glucose from the liver. It does this by interfering with the energy production processes in liver cells. This means that these cells start to rely more on glucose as an energy source. This leads to lower glucose production and consequently lower blood sugar levels. Metformin also reduces glucose absorption in the intestines and enhances glucose uptake in muscle and fat tissues, which helps to further reduce blood sugar levels. When used in combination, Sitagliptin and Metformin work together to regulate insulin production and manage glucose metabolism, providing an effective treatment option for patients with type 2 diabetes who require help in managing their blood sugar levels.

Metformin:

Unveiling its multifaceted uses and transformative applications as follows:

• Treatment of type 2 diabetes mellitus in adults
• Sitagliptin 50mg tablets are used alongside Metformin 850mg to boost insulin levels
• The combination of sitagliptin and metformin targets different aspects of diabetes pathophysiology and has complementary effects on glycemic control."
• Lowering blood sugar levels back to a normal range
• Reducing the risk of developing complications related to diabetes like blindness or amputation
• Sitagliptin works by increasing the levels of natural substances in your body called incretins, which help to control blood sugar levels
• Metformin works by reducing the amount of sugar your liver makes and by making your body more sensitive to insulin

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For treating type 2 diabetes, the recommended dose of Sitagliptin is 50 mg once or twice daily, and for Metformin, it is 850 mg twice a day.
• It is important to follow the dosage instructions provided by your physician, as it will depend on several factors like age, weight, severity of condition, and other medical conditions you may have.

An overdose of sitagliptin and metformin can produce some unwanted symptoms such as hypoglycemia (low blood sugar) or gastrointestinal problems. It is imperative to seek medical attention immediately if you suspect an overdose. For immediate treatment, the individual will require monitoring and stabilization, and glucose supplementation can raise blood sugar levels if they are too low. Additionally, medications like loperamide may be used to treat gastrointestinal symptoms such as diarrhea. In more severe cases, gastric lavage may be necessary to induce vomiting and remove the excess medication from the body, and activated charcoal may be used to prevent the absorption of the remaining drug from the gastrointestinal tract.

When it comes to managing your diabetes with the combination therapy of Sitagliptin 50mg and Metformin 850mg, it is important to adhere to the prescribed dosage and timing as instructed by your healthcare provider. In case you miss a dose, you have two options. First, if it is not too late, take the missed dose as soon as possible unless it is closer to your next scheduled dose. Secondly, if you miss a dose and it is almost time for your next scheduled dose, it is better to skip the missed dose and resume your regular schedule without doubling up to avoid any chance of an overdose. Regardless of what happens, please ensure you discuss any changes with your healthcare provider and listen carefully to their instructions, as they know your medical history and can advise you best.

When taking Sitagliptin 50mg and Metformin 850mg, it's important to follow your doctor's directions carefully. Here are some key guidelines to keep in mind:

Discerning instances where this medication may not be appropriate:

• If you are allergic to Sitagliptin and Metformin or any of the ingredients in these medications.
• If you have any type of kidney disease or impaired kidney function.
• If you have severe nausea, vomiting, or diarrhea that prevents you from keeping oral medications down.
• If you have low blood sugar (hypoglycemia) or a predisposition to low blood sugar (such as if you have diabetes treated with insulin).
• If you have surgery coming up or are otherwise at risk of low blood sugar levels.
• If you have a history of pancreatitis (inflammation of the pancreas).
• If you have renal impairment (reduced kidney function), specifically an estimated glomerular filtration rate (eGFR) of less than 45 mL/min.

Unraveling the side effects lurking behind this medications are as follows:

• Hypoglycemia (low blood sugar)
• Upper respiratory tract infection
• Headache
• Diarrhea
• Nausea
• Vomiting
• Decreased appetite
• Weight loss

When storing Sitagliptin 50mg and Metformin 850mg, it is important to follow these guidelines carefully to ensure the medications remain effective. These drugs should be kept at room temperature, ideally in a cool, dry place that is away from direct heat and light. Bathrooms and kitchens, where moisture and heat are prevalent, should be avoided as storage areas. To keep these medications safe and secure, be sure to store them out of reach and sight of children. It is recommended to keep them in their original containers or packaging, ensuring to tightly close the caps or lids after each use to prevent contamination or spillage. This will also help protect the drugs from any moisture or dust buildup.It is critical to regularly check the expiration date on the medication and discard any expired drugs. Should you have any questions or concerns about storing these medications, be sure to consult your healthcare provider or pharmacist for further guidance.