Graset (100mg) 30 Tablets

Sertraline 100mg tablets primarily exert their therapeutic effects through selective serotonin reuptake inhibition (SSRIs). This mechanism of action involves blocking the reabsorption of serotonin, a neurotransmitter, in the brain. By inhibiting the serotonin transporter (SERT), sertraline increases the availability of serotonin in the synaptic cleft, allowing for enhanced serotonin signaling. This elevation in serotonin levels is believed to play a crucial role in regulating mood, emotions, and various cognitive functions. Sertraline's selective action on serotonin reuptake helps restore the balance of this neurotransmitter, contributing to its effectiveness in treating depression, anxiety disorders, and other psychiatric conditions where serotonin dysfunction is implicated.

Antidepressant (SSRI)

Tablet

The following are the uses of Sertraline 100mg Tablet:

• Used for treating depression, helping to alleviate symptoms like persistent sadness, loss of interest, and low mood.
• Used for managing anxiety disorders, reducing excessive worry and fear in conditions like generalized anxiety disorder.
• Used for panic disorder, providing relief from sudden episodes of intense fear and panic attacks.
• Used for obsessive-compulsive disorder (OCD), assisting in managing repetitive thoughts and behaviors.
• Used for post-traumatic stress disorder (PTSD), aiding in the healing process after traumatic events.
• Used for premenstrual dysphoric disorder (PMDD), alleviating severe PMS symptoms.
• Used for social anxiety disorder, enabling individuals to manage social situations with reduced anxiety.
• Used for certain eating disorders, supporting recovery and improving mood regulation.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Sertraline hydrochloride 100mg is the active ingredient in Zoloft, a popular antidepressant medication.
• The appropriate dose of Sertraline depends on individual factors and the condition being treated.
• Depression and Anxiety- Common adult doses range from 50-200mg per day, usually divided into 2 doses.
• OCD- Higher doses from 150-200mg per day may be used.
• Serotonin Syndrome- For this dangerous condition, lower doses around 50mg are recommended.
• Elderly or hepatically impaired- Lower doses and monitoring are essential due to decreased clearance.
• It's crucial to follow medical advice and not self-adjust dose without professional guidance, as there are many factors and risks involved.

In the case of an overdose of Sertraline 100mg Tablets, individuals may experience an array of symptoms. These can include heightened drowsiness, dizziness, and gastrointestinal issues such as nausea and vomiting. In more severe cases, rapid heart rate, tremors, and even seizures may occur. Prompt medical intervention is essential, and individuals should seek emergency care without delay to mitigate the potential risks associated with Sertraline overdose.

In the case of a missed dose of Sertraline 100mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may advise you to restart the medication at a lower dose or provide alternative instructions to ensure a safe and effective treatment plan.

To take Sertraline 100mg Tablets, swallow the tablet whole with a full glass of water, preferably in the morning or as directed by your healthcare professional, and do not crush, chew, or break the tablet to ensure proper absorption and effectiveness.

Here are the situations when Sertraline 100mg Tablet should not be taken:

• Avoid if you are allergic to Sertraline or similar medications, such as other selective serotonin reuptake inhibitors (SSRIs).
• Do not use if you are currently taking monoamine oxidase inhibitors (MAOIs) or have taken them within the last 14 days.
• Contraindicated in individuals with a history of serotonin syndrome or those who are taking other medications that increase serotonin levels.
• Should not be used in patients with uncontrolled narrow-angle glaucoma.
• Not suitable for individuals with a history of bleeding disorders or those taking blood-thinning medications.
• Avoid if you have a history of seizures or epilepsy.
• Do not use in patients with severe liver impairment.
• Contraindicated during the initial recovery phase following a heart attack.

The side effects of Sertraline 100mg Tablet may include:

• Nausea and vomiting
• Diarrhea or constipation
• Dry mouth
• Dizziness or lightheadedness
• Insomnia or excessive sleepiness
• Headaches
• Sexual dysfunction, including decreased libido or delayed orgasm
• Increased sweating

Following are the precautions and warnings:

• Sertraline 100mg Tablet should not be started or stopped abruptly without medical supervision. Gradual dose adjustments are recommended to minimize side effects.
• Patients with a history of suicidal thoughts or behavior should be closely monitored, especially during the initial weeks of treatment, as Sertraline may increase the risk of suicidal tendencies.
• Sertraline can cause an increase in serotonin levels, leading to a potentially life-threatening condition called Serotonin Syndrome. Discontinue use if symptoms such as agitation, hallucinations, rapid heart rate, or coordination problems occur.
• This medication may cause a rare but serious allergic reaction. Seek immediate medical attention if you experience symptoms like rash, itching, swelling, severe dizziness, or trouble breathing.
• It may cause an increase in blood pressure, so patients with hypertension should be monitored regularly.
• Sertraline can impact sexual function and may cause sexual side effects in both men and women. Discuss any concerns with your healthcare provider.
• Patients with liver or kidney disease should exercise caution and inform their doctor, as Sertraline dosage may need adjustment.

Following are the drug interactions for Sertraline 100mg Tablet:

• Sertraline may increase serotonin levels when taken with other serotonergic drugs like triptans, SNRIs, or other SSRIs, leading to serotonin syndrome.
• It is contraindicated to use Sertraline with Monoamine Oxidase Inhibitors (MAOIs), as it can result in severe reactions including serotonin syndrome.
• Anticoagulants such as warfarin may have their effects enhanced, increasing the risk of bleeding.
• Central nervous system depressants (e.g., benzodiazepines, opioids) can have their effects potentiated, leading to increased sedation and respiratory depression.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) might elevate the risk of bleeding when used concurrently with Sertraline.
• Sertraline can impact the metabolism of certain medications, including some anticonvulsants and antipsychotics, potentially raising their blood levels and side effects.
• Drugs that influence liver enzymes may alter Sertraline's metabolism, requiring close monitoring.

Following are the food interactions for Sertraline 100mg Tablet:

• Grapefruit and grapefruit juice should be consumed with caution as they may increase the levels of Sertraline in the blood, leading to higher chances of side effects.
• Alcohol intake should be minimized or avoided as it can increase the sedative effects, causing increased drowsiness and dizziness.
• Avoid excessive consumption of foods rich in tyramine (aged cheeses, cured meats, fermented foods) as Sertraline may interact, leading to high blood pressure.
• Caffeine intake should be monitored as it can increase anxiety and restlessness, especially when taken in large amounts.
• Avoid herbal supplements like St. John's Wort, as it can decrease Sertraline's effectiveness and increase the risk of serotonin syndrome.
• Do not consume high-sodium foods regularly, as Sertraline may cause sodium retention in some cases.
• There is no specific food restriction, but maintaining a balanced diet is recommended for overall well-being.
• Always consult your healthcare provider for personalized advice regarding dietary considerations while taking Sertraline.

Sertraline 100mg Tablets should be stored in a secure and dry location, away from heat and direct sunlight. Maintain a consistent room temperature, ideally between 68°F and 77°F (20°C and 25°C), to ensure the medication's integrity. Keep the tablets in their original container, tightly sealed, to prevent exposure to moisture and contamination. It is crucial not to store them in the bathroom due to the potential for humidity. When disposing of unused or expired tablets, do not flush them or throw them into the trash. Instead, follow local guidelines or consult a pharmacist for safe disposal methods to protect the environment and prevent misuse. Keep the medication out of children's reach to avoid accidental consumption, and always exercise caution when handling and storing Sertraline tablets.

Following are the quick tips for Sertraline 100mg Tablet:

• Consult a doctor for prescription and dosage instructions tailored to your condition.
• Take the tablet as directed, typically once daily, with or without food.
• Swallow the tablet whole; do not crush, chew, or break it.
• Maintain a consistent routine by taking the medication at the same time each day.
• Avoid alcohol consumption while on this medication to prevent adverse effects.
• Inform your doctor about all medications you're taking to prevent potential interactions.
• Store the tablets at room temperature, away from moisture and sunlight.
• Do not share your medication with others, even if they have similar symptoms.

When taking Sertraline Hydrochloride 100mg, it is essential to undergo laboratory tests to monitor your health and ensure the medication's effectiveness. Lab tests play a pivotal role in safeguarding your wellbeing and making informed decisions about your treatment.These tests can be broken down into three categories: