Herbesser (60mg) 30 Tablets

Diltiazem 60mg Tablet primarily exerts its therapeutic effects through its action as a calcium channel blocker. It selectively inhibits calcium influx into cardiac and vascular smooth muscle cells by binding to and blocking L-type calcium channels. By reducing calcium entry, diltiazem impedes the process of calcium-induced calcium release, which is crucial for muscle contraction. This inhibition leads to a decrease in myocardial contractility, slowing the heart rate, and reducing the force of contraction. Consequently, the medication effectively lowers blood pressure by inducing peripheral vasodilation and reducing cardiac workload. Additionally, diltiazem's action on vascular smooth muscle promotes relaxation, further contributing to its antihypertensive and angina-relieving properties.

Diltiazem 60mg

Calcium channel blocker.

gel

The following are the uses of Diltiazem 60mg Tablet:

• Used for managing high blood pressure, helping to lower and control hypertension.
• Used for treating chest pain (angina), providing relief and preventing angina attacks.
• Used for treating irregular heart rhythms (arrhythmias) by regulating the heart's electrical activity.
• Used for managing heart rate in conditions like atrial fibrillation, restoring a regular heartbeat.
• Used for reducing the risk of future cardiovascular events, such as heart attacks and strokes.
• Used for improving blood flow in conditions like Raynaud's phenomenon, easing symptoms.
• Used for managing certain types of headaches, particularly migraine-related vasospasm.
• Used for its calcium channel blocking properties, relaxing blood vessels and improving circulation.

The following dosage can be followed:

• Hypertension- For the treatment of high blood pressure, Herbesser (diltiazem) is usually prescribed at an initial dose of 180 mg to 240 mg once daily in extended-release form. The dose may be adjusted based on the patient’s response, with a typical range of 180 mg to 360 mg per day.
• Angina (Chest Pain)- For chronic stable angina, the usual starting dose of Herbesser is 30 mg four times a day in the immediate-release form, or 120 mg to 180 mg once daily in extended-release form. The dosage may be gradually increased depending on how the patient responds, up to a maximum of 360 mg per day.

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In the case of an overdose of Diltiazem 60mg Tablets, it is important to recognize the potential severity of the situation. Symptoms may include a rapid drop in blood pressure, leading to dizziness and fainting. Additionally, the overdose can cause an irregular heartbeat, nausea, and extreme fatigue. Prompt medical intervention is essential, as healthcare professionals can provide the necessary treatment to manage these symptoms and prevent potential complications from the excessive dosage.

In the case of a missed dose of Diltiazem 60mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may advise you to restart the medication or provide alternative instructions to ensure the proper management of your condition.

To take Diltiazem 60mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, ensuring not to crush, chew, or break the tablet.

Following are the conditions when Diltiazem 60mg Tablet should not be taken:

• Avoid if you have a known allergy to Diltiazem or other calcium channel blockers.
• Do not use if you have a severe heart condition, such as heart block, sick sinus syndrome, or severe aortic stenosis.
• Contraindicated in patients with low blood pressure (hypotension).
• Should not be used if you have severe liver disease or impaired liver function.
• Avoid if you have a condition called left ventricular dysfunction.
• Not suitable for patients with a type of irregular heartbeat called atrial flutter or atrial fibrillation, unless specifically indicated.
• Do not use if you have recently had a heart attack and have certain complications.
• Contraindicated in patients with a history of heart failure.

The side effects of Diltiazem 60mg Tablet may include:

• Dizziness or lightheadedness
• Fatigue or weakness
• Headache
• Nausea or vomiting
• Constipation
• Slow heart rate (bradycardia)
• Swelling in the legs or ankles
• Flushing (reddening of the face)

Following are the precautions and warnings for Diltiazem 60mg Tablet:

• Patients with known hypersensitivity or allergy to Diltiazem or other calcium channel blockers should not take this medication.
• Diltiazem can cause a significant drop in blood pressure, so caution is advised in patients with hypotension or those taking antihypertensive medications.
• Liver function should be monitored during treatment, especially in patients with pre-existing liver conditions.
• This medication may affect cardiac function, and ECG monitoring is recommended, particularly in patients with heart disease.
• Elderly patients may be more susceptible to the side effects of Diltiazem, and dosage adjustments might be necessary.
• Diltiazem can interact with other medications, including beta-blockers and digoxin, so it's crucial to inform your doctor of all medications you are taking.
• Patients should be advised to avoid grapefruit and grapefruit juice as they can affect the metabolism of Diltiazem.

Following are the drug interactions for Diltiazem 60mg Tablet:

• Concomitant use with beta-blockers, such as metoprolol or propranolol, may enhance the risk of bradycardia, hypotension, and heart block.
• Diltiazem may increase plasma levels of statins, such as simvastatin or atorvastatin, increasing the risk of myopathy or rhabdomyolysis.
• Co-administration with CYP3A4 inducers, such as rifampicin or carbamazepine, may reduce Diltiazem levels and its therapeutic effect.
• CYP3A4 inhibitors, such as ketoconazole or erythromycin, may increase Diltiazem levels, leading to an increased risk of adverse effects.
• Concomitant use with digoxin may increase digoxin plasma levels, requiring close monitoring for toxicity.
• Diltiazem may enhance the effects of antihypertensive drugs, such as ACE inhibitors or diuretics, leading to an increased risk of hypotension.
• Drugs that prolong the QT interval, such as amiodarone or sotalol, may increase the risk of cardiac arrhythmias when taken with Diltiazem.

Following are the food interactions to consider with Diltiazem 60mg Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can increase the levels of Diltiazem in the blood, potentially leading to an increased risk of side effects.
• Alcohol intake should be limited or avoided as it may exaggerate the effects of Diltiazem, causing excessive lowering of blood pressure and increased heart rate.
• Consuming high-fat meals while taking Diltiazem can slightly decrease the absorption of the medication, so it is advisable to maintain a consistent diet.
• Dairy products like milk and yogurt may interfere with the absorption of Diltiazem, so it is recommended to separate them by a few hours.
• Avoid excessive consumption of licorice as it can decrease the effectiveness of Diltiazem by reducing its levels in the body.
• Caffeinated beverages like coffee and tea might increase blood pressure and counteract the effects of Diltiazem, so moderation is key.
• Ensure a balanced diet rich in fiber and maintain hydration by drinking adequate water to support the cardiovascular system while on Diltiazem therapy.
• Always consult your healthcare provider for personalized advice regarding specific food interactions and dietary adjustments during Diltiazem treatment.

Diltiazem 60mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area, away from direct sunlight, moisture, and extreme temperatures. It is crucial to keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to environmental factors. Always check the expiration date on the packaging, and never use the medication if it is past its expiry. When disposing of unused or expired tablets, do not flush them down the toilet or dispose of them in regular household waste. Instead, follow local guidelines for pharmaceutical waste disposal or consult your pharmacist for appropriate methods to ensure the safe and environmentally friendly disposal of Diltiazem 60mg Tablets. Keep the medication out of the sight and reach of children and pets to prevent accidental ingestion, which can be harmful.

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Following are the quick tips for Diltiazem 60mg Tablet:

• Consult your doctor before starting this medication, especially if you have liver or kidney issues.
• Take the tablet as directed by your doctor, typically 3-4 times daily.
• Swallow the tablet whole with a full glass of water, do not crush or chew.
• Maintain a consistent schedule for taking the tablet to ensure its effectiveness.
• Inform your doctor about all medications you are currently taking to avoid interactions.
• Do not abruptly stop taking the tablet; consult your doctor for dosage adjustments.
• Store the medication in a cool, dry place, away from direct sunlight.