Hivate (0.1%) 30ml Lotion

Mometasone furoate, the active ingredient in the lotion, is a synthetic corticosteroid that primarily exhibits its anti-inflammatory effects by inhibiting the production of various pro-inflammatory mediators. It binds to cytoplasmic glucocorticoid receptors in target cells, and the resulting complex then translocates into the cell nucleus, where it regulates gene expression. Mometasone furoate downregulates the expression of several pro-inflammatory genes, including those encoding cytokines, chemokines, and enzymes involved in the synthesis of inflammatory mediators. By suppressing the release of these inflammatory substances, mometasone furoate effectively reduces inflammation, pruritus (itching), and the associated symptoms in various skin conditions.

Corticosteroid.

Lotion

The following are the uses of Mometasone Furoate Lotion:

• Used for treating inflammatory skin conditions like eczema and dermatitis.
• Used for relieving itching, redness, and swelling.
• Used for managing skin allergies and rashes.
• Used for long-term control of symptoms and prevention of flare-ups.
• Used for reducing skin inflammation and irritation.
• Used for improving skin texture and appearance.
• Used for providing relief from discomfort and pain associated with skin inflammation.
• Used for complementing other treatments for skin conditions.

Follow these dosage instructions:

• Adults and children 2 years of age and older

Apply to the affected area of the skin once a day.

• Children younger than 2 years of age

Use is not recommended.

In the case of an overdose of Mometasone Furoate Lotion, it is important to be aware of potential side effects. Excessive use may lead to skin irritation, redness, or a burning sensation. If ingested, it could cause oral or throat discomfort. Promptly contact a healthcare professional or poison control center for guidance and to determine the best course of action. They will provide specific instructions based on the circumstances of the overdose.

In the case of a missed dose of Mometasone Furoate Lotion, it is important to apply it as soon as you remember. However, if it's almost time for your next scheduled application, skip the missed dose and continue with your regular schedule. Do not apply extra lotion to make up for the missed dose, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or alarms to help you stay on track with your medication routine. It is essential to maintain a consistent application schedule for the medication to be most effective.

To apply Mometasone Furoate Lotion, gently squeeze a small amount onto your fingertip and apply a thin layer to the affected areas of the skin once daily, carefully following the instructions provided by your healthcare professional or as directed on the product label.

Following are the conditions/situations when Mometasone Furoate Lotion should not be used:

• Do not use if you are allergic to mometasone or any other corticosteroids.
• Avoid using on skin with conditions like rosacea, acne, open sores, or skin infections.
• Not recommended for children under a certain age (consult a doctor for specific age restrictions).
• Do not use on skin that is irritated, severely burned, or affected by certain skin disorders.
• Avoid using on the face, underarms, or groin area unless directed by a healthcare professional.
• Do not use if you have a skin reaction to any of the lotion's ingredients.
• Do not cover the treated skin area with a bandage or wrap, as it may increase the absorption of the medication.
• Not suitable for individuals with a history of thinning skin or easy bruising.

The side effects of Mometasone Furoate Lotion may include:

• Skin irritation or itching at the application site
• Redness or dryness of the skin
• Burning or stinging sensation
• Thinning of the skin
• Acne or pimples
• Contact dermatitis
• Allergic reactions (such as rash, hives, itching, or difficulty breathing)
• Skin discoloration or hypopigmentation

Following are the precautions and warnings for Mometasone Furoate Lotion:

• Avoid using the lotion on the face, eyes, or sensitive areas of the body unless directed by a healthcare professional.
• Do not use the lotion on skin that is broken, infected, or severely irritated.
• It is important to use the medication as directed and not to exceed the prescribed dosage.
• Do not cover the treated area with bandages or tight clothing as it may increase the absorption of the medication.
• Wash your hands thoroughly after applying the lotion to avoid accidental transfer to other areas.
• Discontinue use and seek medical attention if you experience any signs of an allergic reaction, such as rash, itching, or difficulty breathing.
• Mometasone Furoate Lotion is a potent corticosteroid; prolonged use or overuse may lead to skin thinning, stretch marks, or other skin changes.

Following are the drug interactions for Mometasone Furoate Lotion:

• It may lead to increased absorption of other topical products when applied simultaneously, potentially increasing the risk of adverse effects.
• Strong CYP3A4 inhibitors, such as ketoconazole, can increase the systemic exposure of mometasone furoate, which may result in increased side effects.
• Avoid using other corticosteroids or immunosuppressants simultaneously, as it may lead to additive effects and increase the risk of immunosuppression.
• Mometasone furoate can reduce the effectiveness of vaccines, including live attenuated vaccines, due to its immunosuppressive properties.
• The use of Mometasone Furoate Lotion with other potent topical corticosteroids may increase the risk of systemic corticosteroid side effects.
• Anticoagulants, like warfarin, may have their effects altered by mometasone furoate, potentially requiring adjustments in dosage.
• The use of this medication with other drugs that suppress the immune system should be closely monitored due to potential additive immunosuppressive effects.

Following are the food interactions for Mometasone Furoate Lotion:

• Avoid consuming grapefruit and grapefruit juice as they may interfere with the medication's metabolism, potentially leading to increased drug levels in the body.
• Alcoholic beverages should be limited or avoided as they can enhance the absorption of Mometasone Furoate, increasing the risk of side effects.
• Dairy products like milk and yogurt might decrease the absorption of the medication, so it is advisable to separate their consumption from the application of the lotion.
• Fatty meals or high-fat foods may also impact the absorption rate of Mometasone Furoate; it is best to maintain a consistent dietary pattern while using this medication.
• Caffeinated beverages like coffee and tea might lead to increased skin sensitivity when used with Mometasone Furoate Lotion; consider reducing their intake.
• While not a direct food interaction, smoking can affect the skin's healing process and reduce the effectiveness of the medication.
• Certain vitamin-rich foods or supplements, especially those containing Vitamin E, might influence the skin's response to the medication; consult your healthcare provider for specific guidance.
• Always follow the instructions provided by your healthcare professional regarding dietary considerations while using Mometasone Furoate Lotion.

Mometasone Furoate Lotion should be stored carefully to maintain its effectiveness and ensure safe disposal. Keep the lotion in a cool, dry place, preferably at room temperature, and protect it from direct sunlight and heat sources like radiators or stoves, as extreme temperatures can impact its quality. Always store it in its original container, tightly sealed, to prevent contamination. Before using the lotion, check the expiration date, and do not use it if it has expired. When it's time to dispose of the medication, do not flush it or pour it down the drain; instead, consult your pharmacist or healthcare provider for the recommended disposal methods in your area. Keep the lotion out of children's reach to prevent accidental exposure.

No

Following are the quick tips for Mometasone Furoate Lotion:

• Wash your hands before and after applying the lotion to maintain hygiene.
• Apply a thin layer to affected areas and gently rub it in.
• Use the lotion as directed, typically once or twice daily, or as prescribed by your doctor.
• Do not apply near eyes, mouth, or open wounds.
• Avoid excessive use and do not cover the treated area with bandages.
• If irritation or redness occurs, discontinue use and consult your healthcare provider.
• Store the lotion at room temperature, away from direct sunlight and moisture.