Hivate (50mcg/Dose) 120 Nasal Spray

Mometasone furoate spray is a corticosteroid that primarily exhibits its anti-inflammatory effects by binding to cytoplasmic glucocorticoid receptors. Upon binding, the activated corticosteroid-receptor complex translocates to the nucleus, where it modulates the expression of various genes involved in the inflammatory response. It inhibits the production and release of pro-inflammatory mediators, including cytokines, enzymes, and adhesion molecules, by interfering with their transcription process. This results in reduced inflammation, decreased vascular permeability, and suppression of immune cell activity in the targeted tissues. The precise mechanism of action contributes to the effectiveness of mometasone furoate spray in alleviating inflammation and managing symptoms associated with certain respiratory conditions.

Corticosteroid spray

Spray

The following are the uses of Mometasone Furoate Spary:

• Used for treating inflammation and allergies in the nose, such as hay fever and allergic rhinitis.
• Used for relieving nasal congestion, sneezing, and itchy, runny nose.
• Used for reducing nasal inflammation and swelling to improve breathing.
• Used for preventing and managing nasal polyps, small growths in the nasal passages.
• Used for treating non-allergic nasal symptoms like those caused by irritants.
• Used for providing long-term control of nasal symptoms when used regularly.
• Used for its anti-inflammatory properties to calm the nasal lining.
• Used for improving overall nasal comfort and reducing discomfort.

To be used as per doctor's prescription

In the case of an overdose of Mometasone Furoate Spray, it is important to remain calm and seek medical advice promptly. Overuse of the spray may lead to increased side effects, such as throat irritation, coughing, or a hoarse voice. If you have accidentally ingested the medication, drink water and contact a healthcare professional or poison control center for guidance. They will provide specific instructions based on the severity of the overdose.

In the case of a missed dose of Mometasone Furoate Spray, it is important to administer the medication as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. It is crucial to maintain a consistent treatment routine, but if you frequently miss doses, contact your healthcare provider for advice on how to manage your medication effectively. Always keep a record of your doses to ensure you stay on track.

To use Mometasone Furoate Spray, gently shake the container, prime the pump if it's your first use, tilt your head forward, insert the tip into one nostril, point the tip away from the nasal septum, depress the pump completely while breathing in gently through the nose, and repeat for the other nostril.

Following are the conditions or circumstances when Mometasone Furoate Spray should not be used:

• Should not be used if you are allergic to mometasone or any other steroid medications.
• Not suitable for individuals with untreated tuberculosis or other untreated infections in the nose or throat.
• Contraindicated in patients with recent nasal surgery or injuries until healing is complete.
• Avoid using if you have a nasal septum perforation or untreated nasal infections.
• Not recommended for individuals with ongoing nasal bleeding of unknown cause.
• Should not be used if you have a history of hypersensitivity reactions to any nasal sprays.
• Avoid using Mometasone Furoate Spray if you have a history of immunosuppression or systemic fungal infections.

The side effects of Mometasone Furoate Spray may include:

• Irritation or dryness in the nose or throat.
• Headache
• Nasal congestion or stuffiness.
• Nose bleeds
• Changes in taste or smell.
• Sneezing
• Throat irritation or discomfort.
• Hoarseness or voice changes.

Following are the precautions and warnings:

• Mometasone Furoate Nasal Spray is for nasal use only. Do not spray in the eyes or mouth, and avoid inhaling the medication deeply into the lungs.
• Before using this medication, inform your doctor if you have any nasal infections, injuries, or recent surgery in the nose or sinus area.
• It is important to use Mometasone Furoate Nasal Spray exactly as prescribed. Do not exceed the recommended dosage or duration of treatment.
• This medication may cause local side effects such as nosebleeds, nasal irritation, or dryness. Contact your doctor if these symptoms persist or worsen.
• Mometasone Furoate Nasal Spray may lead to a reduction in the body's ability to fight infections. Inform your doctor if you have any signs of infection or experience frequent or severe infections.
• Children using this medication should be supervised by an adult to ensure proper usage and to prevent accidental ingestion.
• If you have a history of glaucoma or cataracts, or if you wear contact lenses, consult your doctor before using this medication as it may cause blurred vision or other eye-related side effects.
• Discontinue use and seek immediate medical attention if you experience any signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing.

Following are the drug interactions for Mometasone Furoate Nasal Spray:

• Co-administration with strong CYP3A4 inhibitors like ketoconazole can increase the risk of systemic side effects.
• Avoid using other intranasal medications or sprays unless directed by a healthcare professional, as it may alter the effectiveness.
• Mometasone may interact with oral corticosteroids, potentially leading to increased systemic exposure and side effects.
• Caution is advised when using Mometasone with other nasal decongestants, as it may increase the risk of nasal irritation and dryness.
• The effectiveness of live vaccines may be reduced when administered concurrently with Mometasone Furoate.
• Blood pressure-lowering medications might have their effect reduced when used with Mometasone.
• Antifungal medications such as ketoconazole may increase the absorption of Mometasone Furoate.

Following are the food interactions for Mometasone Furoate Spray:

• Avoid consuming grapefruit and grapefruit juice as they may influence the drug's effects by altering liver enzyme activity, potentially affecting the metabolism of Mometasone Furoate.
• Alcohol intake should be limited as it can increase the risk of side effects such as dizziness, drowsiness, and throat irritation.
• Dairy products like milk and yogurt might interfere with the absorption of Mometasone Furoate, so it's advisable to maintain a gap of at least 2 hours between the medication and dairy consumption.
• Spicy foods and hot beverages should be consumed with caution as they may exacerbate throat irritation or cough, especially if the spray is accidentally inhaled.
• High-fat meals can potentially slow down the absorption of Mometasone Furoate, leading to delayed onset of action.
• Avoid caffeine-rich foods and beverages as they may increase the heart rate and exacerbate any existing palpitations or nervousness caused by the medication.
• Consuming sugary foods and drinks might reduce the effectiveness of the spray by promoting the growth of oral yeast infections, which are a potential side effect of corticosteroids.
• It is advisable to maintain a balanced diet and ensure adequate hydration while using Mometasone Furoate Spray to support overall health and well-being.

Mometasone Furoate Spray should be stored in a cool and dry place, preferably at room temperature, ensuring it is not exposed to direct sunlight or extreme temperatures. Keep the spray bottle tightly sealed to maintain its integrity and prevent contamination. It is crucial to check the expiration date on the packaging regularly and discard any expired or unused medication responsibly. Do not dispose of the spray by flushing it down the toilet or pouring it into drainage systems. Instead, consult your local pharmacist or healthcare professional for guidance on appropriate disposal methods. Remember to keep the medication away from children to prevent accidental exposure or ingestion.

No

Following are the quick tips for Mometasone Furoate Spray:

• Wash your hands before using the spray to maintain hygiene.
• Blow your nose gently to clear any blockage before application.
• Aim the spray tip towards the affected nostril and depress the pump fully.
• Inhale gently while spraying to ensure the medication reaches the nasal passages.
• Avoid blowing your nose immediately after application for better absorption.
• Clean the spray nozzle regularly with a soft, dry tissue to prevent clogging.
• Store the spray at room temperature, away from direct sunlight and moisture.