Hivate (0.1%) 10g Ointment

Mometasone furoate ointment, a synthetic corticosteroid, exerts its therapeutic effects primarily through its anti-inflammatory and immunosuppressive properties. It binds to cytoplasmic glucocorticoid receptors in target cells, resulting in the modulation of various genes involved in inflammation. By inhibiting the production and release of pro-inflammatory mediators such as cytokines and leukotrienes, mometasone furoate reduces inflammation, itching, and allergic reactions. This corticosteroid also stabilizes mast cells, preventing the release of histamine and other inflammatory substances. Additionally, it suppresses the immune response by inhibiting T-cell activation and proliferation, leading to a reduction in the symptoms associated with certain skin conditions.

Corticosteroid ointment

Ointment

The following are the uses of Mometasone Furoate Ointment:

• Used for treating inflammatory skin conditions like eczema and psoriasis, reducing redness, itching, and swelling.
• Used for managing allergic reactions on the skin, minimizing rashes and discomfort.
• Used for alleviating skin inflammation and irritation caused by various factors, including insect bites and contact dermatitis.
• Used for providing relief from itching and discomfort associated with specific skin disorders.
• Used for long-term management of chronic skin conditions, helping to prevent flare-ups.
• Used for its potent anti-inflammatory properties to calm and soothe irritated skin.
• Used for restoring the skin's barrier function, promoting healing and reducing the risk of infection.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Nasal polyps- Age Range- 12 years and older; Dosage- 200 mcg (2 sprays in each nostril) once daily.
• Allergic rhinitis (hay fever)- Age Range- 12 years and older; Dosage- 50 mcg (1 spray in each nostril) once daily.
• Corticosteroid-resistant ulcerative colitis- Age Range- Adults; Dosage- 400 mcg (4 sprays in each nostril) twice daily.

In the case of an overdose of Mometasone Furoate Ointment, it is important to remain calm and take appropriate action. Although rare, excessive use may lead to increased side effects such as skin irritation, redness, or burning. If a large amount has been ingested, contact a healthcare professional or a poison control center for guidance. Promptly seek medical advice to ensure proper treatment and to address any potential health risks associated with the overdose.

In the case of a missed dose of Mometasone Furoate Ointment, it is important to apply it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply extra ointment to make up for the missed dose. If you miss multiple doses, contact your healthcare provider for guidance on how to get back on track with your treatment plan. It's generally best to maintain a consistent application schedule for optimal effectiveness.

To apply Mometasone Furoate Ointment, clean and dry the affected skin area, then gently apply a thin layer of the ointment, rubbing it in completely as directed by your healthcare provider, typically once daily or as prescribed.

Here are the conditions or situations when Mometasone Furoate Ointment should not be used:

• Avoid using if you have a known allergy or hypersensitivity to mometasone furoate or any of the ingredients in the ointment.
• Not recommended for use on the face, underarms, or groin area unless directed by a healthcare professional.
• Do not use on skin that is broken, infected, or has open wounds.
• Avoid using on skin conditions like rosacea, acne, perioral dermatitis, or skin thinning.
• Do not use to treat diaper rash.
• Not suitable for children under 2 years of age without medical advice.
• Do not use for longer than the prescribed duration or for conditions other than those for which it was prescribed.

The side effects of Mometasone Furoate Ointment may include:

• Burning or itching at the application site
• Dry skin or irritation
• Skin redness or discoloration
• Thinning of the skin
• Stretch marks
• Acne or pimples
• Allergic reactions (skin rash, itching, swelling)
• Increased risk of skin infections

Following are the precautions and warnings for Mometasone Furoate Ointment:

• Avoid applying Mometasone Furoate Ointment to the eyes, mouth, or nose. It is strictly for external use only.
• This medication is not recommended for children under 2 years of age without medical supervision.
• If you have a known allergy to mometasone furoate or any other ingredients in the ointment, do not use it.
• Use with caution in patients with skin infections or conditions like rosacea or perioral dermatitis, as it may worsen these conditions.
• Prolonged use of corticosteroids like mometasone furoate may lead to skin thinning, stretch marks, or skin discoloration.
• Avoid using occlusive dressings or bandages over the treated area unless directed by a healthcare professional.
• Patients with diabetes should monitor their blood sugar levels as corticosteroids can affect glucose metabolism.
• Consult a doctor if you are pregnant, planning to become pregnant, or breastfeeding before using this medication.

Following are the drug interactions for Mometasone Furoate Ointment:

• Strong CYP3A4 inhibitors like ketoconazole, itraconazole, or clarithromycin can increase the concentration of mometasone, potentially leading to increased corticosteroid effects and adrenal suppression.
• Combining with other topical corticosteroids or potent immunosuppressants may enhance local adverse effects and increase the risk of systemic absorption.
• Mometasone may increase the risk of infections, so caution is advised when using it with immunosuppressive medications.
• The use of Mometasone Furoate Ointment with other potent topical agents, such as retinoids or other keratolytic agents, may cause additive skin irritation.
• Live vaccines should be avoided as Mometasone can suppress the immune response, reducing vaccine effectiveness.
• Topical calcineurin inhibitors, like tacrolimus or pimecrolimus, when used with Mometasone, may increase the risk of skin atrophy and other adverse effects.
• Caution with drugs affecting CYP3A4 metabolism, as they may alter mometasone's effects.

Following are the food interactions for Mometasone Furoate Ointment:

• Mometasone Furoate Ointment should be used with caution in patients with a history of gastrointestinal diseases, as it may cause gastrointestinal irritation.
• The use of alcohol is not recommended while using this medication, as it can increase the risk of gastrointestinal side effects like stomach bleeding or ulcers.
• Avoid eating grapefruit or drinking grapefruit juice during treatment, as it may increase the levels of the drug in the body, potentially leading to increased side effects.
• High-fat meals can decrease the absorption of Mometasone Furoate; thus, it is advisable to avoid high-fat foods before applying the ointment.
• Caffeine-rich foods and beverages may increase the absorption of Mometasone Furoate, so it's best to limit their consumption.
• Some foods like kale, spinach, and other leafy greens may interact with the medication, as they contain high levels of vitamin K, which can reduce the drug's effectiveness.
• It is generally recommended to maintain a balanced diet and stay well-hydrated during treatment to support overall skin health.
• Always consult your healthcare provider for specific dietary recommendations and to discuss any potential food interactions.

Mometasone Furoate Ointment should be stored with care to ensure its effectiveness and safety. Keep the ointment in a cool, dry place, preferably at room temperature, and away from direct exposure to sunlight or excessive heat. Maintain the original packaging, ensuring it remains tightly sealed to prevent contamination. Avoid storing it in humid areas like bathrooms or near water sources. Always check the expiration date, and never use the ointment past its expiry. When disposing of unused or expired ointment, do not flush or pour it down the drain; instead, follow local guidelines or consult a pharmacist for safe disposal methods. Keep the medication away from children to prevent accidental exposure or ingestion.

Following are the quick tips for Mometasone Furoate Ointment:

• Wash your hands before and after applying the ointment to maintain hygiene.
• Clean and dry the affected area before applying the ointment.
• Apply a thin layer, gently rubbing it into the skin, ensuring complete coverage.
• Do not cover the treated area with bandages or tight clothing to allow it to breathe.
• Avoid applying the ointment to sensitive areas like the face, underarms, or groin unless directed by your doctor.
• Do not use the ointment for longer than prescribed to avoid potential side effects.
• Store the ointment at room temperature, away from direct sunlight and moisture.

Mometasone furoate is a steroid that serves as a potent anti-inflammatory agent, making it an ideal treatment option for eczema and psoriasis, conditions characterized by inflamed skin. While it works wonders for many, its use may come with potential side effects, notably immune system suppression, increased risk of infections, and laboratory test anomalies, especially with prolonged use. When considering mometasone furoate, it is crucial to disclose all pertinent medical history to your healthcare provider. Any history of allergies or underlying conditions, especially infections, must be disclosed to ensure an informed treatment approach. To ensure the safety and effectiveness of this medication, your doctor may opt to conduct a series of specific tests, such as: