Itaglip-Plus (50/850mg) 14 Tablets

Sitagliptin is a drug used to treat patients with type 2 diabetes. It works by blocking the breakdown of incretins, which are hormones that help stimulate insulin production in response to rising blood glucose levels. By enhancing incretin levels, Sitagliptin helps to increase insulin secretion and reduce blood sugar levels. Additionally, Sitagliptin also slows down the rate at which food moves from the stomach to the intestine, helping to keep you full for longer and potentially leading to weight loss. Metformin is another common medication used to treat type 2 diabetes. It works primarily by inhibiting the production of glucose from the liver. It does this by interfering with the energy production processes in liver cells. This means that these cells start to rely more on glucose as an energy source. This leads to lower glucose production and consequently lower blood sugar levels. Metformin also reduces glucose absorption in the intestines and enhances glucose uptake in muscle and fat tissues, which helps to further reduce blood sugar levels. When used in combination, Sitagliptin and Metformin work together to regulate insulin production and manage glucose metabolism, providing an effective treatment option for patients with type 2 diabetes who require help in managing their blood sugar levels.

Metformin:

Unveiling its multifaceted uses and transformative applications as follows:

• Sitagliptin 50mg is used in treating type 2 diabetes and in controlling blood sugar levels in adults with type 2 diabetes
• Metformin Hydrochloride 850mg is used for the treatment of type 2 diabetes mellitus in overweight and obese adults and in treating polycystic ovary syndrome (PCOS) in women who are overweight or obese
• These medications are not to be used in the treatment of type 1 diabetes or diabetic ketoacidosis
• These medications are not for the treatment of obesity or weight loss
• Sitagliptin should be taken with food to help reduce stomach upset and Metformin Hydrochloride should be taken with a meal to help reduce stomach upset

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For Sitagliptin 50mg- Take one tablet with or without food, once or twice a day.
• For Metformin Hydrochloride 850mg- The usual starting dose is 500 mg once or twice a day (with or without food).

An overdose of sitagliptin and metformin may result in a variety of adverse effects, including lactic acidosis, hypoglycemia, abdominal pain, nausea, vomiting, weakness, and mild dizziness. If a patient experiences any of these symptoms, it is crucial to seek immediate medical attention. Treatment for an overdose typically involves several steps to address the situation and monitor the patient's recovery. Firstly, if the overdose occurred recently, doctors may induce emesis, or vomiting, to expel the drugs from the patient's stomach. In more severe cases, life support measures such as the administration of activated charcoal may be used to prevent the absorption of the drugs. Following this, gastric lavage, or stomach pumping, is conducted to flush the contents of the stomach. In cases of severe metformin overdose, hemodialysis can be utilized to enhance the removal of metformin from the body. Throughout the treatment process, it is essential to monitor the patient's vital signs and general condition, and to adjust the treatment plan as needed. Consistent monitoring of blood glucose levels, as well as electrolyte levels like potassium, sodium, and calcium, is necessary to identify any imbalances and ensure they are restored to healthy levels. Close observation and further management by medical professionals is required to address any complications and ensure a speedy recovery. It is important to note that this information should only be used for informational purposes .

It is important to take your medication as soon as possible if you miss a dose. If it is almost time for your next dose, then you should skip the missed dose and take the next dose as planned. Do not take extra doses to make up for the missed one. It is critical to maintain consistent medication intake for diabetes, as it is necessary to stabilize blood sugar levels and prevent complications. It is recommended that you speak with your doctor about any further questions or concerns regarding missed doses, and in general, should you find yourself in this situation.

When taking Sitagliptin 50mg and Metformin Hydrochloride 850mg, it is important to follow the directions provided by your doctor or the instructions on your prescription label. Here is a general guide to help you understand how to take these medications:

Discerning instances where this medication may not be appropriate:

• If you are allergic to Sitagliptin and Metformin or any of the ingredients in these medications.
• If you have any type of kidney disease or impaired kidney function.
• If you have severe nausea, vomiting, or diarrhea that prevents you from keeping oral medications down.
• If you have low blood sugar (hypoglycemia) or a predisposition to low blood sugar (such as if you have diabetes treated with insulin).
• If you have surgery coming up or are otherwise at risk of low blood sugar levels.
• If you have a history of pancreatitis (inflammation of the pancreas).
• If you have renal impairment (reduced kidney function), specifically an estimated glomerular filtration rate (eGFR) of less than 45 mL/min.

Unraveling the side effects lurking behind this medications are as follows:

• Nausea
• Vomiting
• Diarrhea
• Increased susceptibility to sunburn
• Dry mouth
• Headaches
• Confusion
• Irritability
• Agitation
• Depression
• Weakness

Sitagliptin 50mg and Metformin Hydrochloride 850mg are two medications often prescribed to patients with type 2 diabetes to manage blood sugar levels. It is important to follow guidelines in order to ensure these medications remain effective and safe to use. Below are some key storage and usage instructions for these drugs: