Kestine (5mg/5ml) 60ml Syrup

Ebastine, the active ingredient in the 5mg/5ml syrup/suspension, is a second-generation H1-receptor antagonist, also known as a histamine blocker. Its primary mechanism of action involves selectively blocking the H1-receptors in the body, particularly those located in the nasal passages, lungs, and skin. By binding to these receptors, Ebastine prevents histamine from attaching to them, thereby inhibiting its effects. This action leads to a reduction in the symptoms associated with allergic reactions, such as sneezing, itching, and nasal congestion. Ebastine is designed to be non-sedating, meaning it does not cause drowsiness like some other antihistamines, as it does not readily cross the blood-brain barrier.

Ebastine 5mg/5ml

Ebastine 5mg/5ml Syrup/Suspension is a second-generation antihistamine.

Suspension

The following are the uses of Ebastine 5mg/5ml Syrup/Suspension:

• Used for treating allergic rhinitis and chronic idiopathic urticaria
• Used to provide relief from symptoms like sneezing, runny nose, and itching
• Used to control allergic reactions and reduce inflammation
• Used for patients with seasonal allergies or year-round allergies
• Used to alleviate skin itching and hives caused by allergies
• Used as a long-term treatment to prevent allergy symptoms
• Used for children and adults with mild to moderate allergies
• Used as an alternative for patients who cannot take tablets

In the case of an overdose of Ebastine 5mg/5ml Syrup/Suspension, individuals may experience symptoms such as drowsiness, dizziness, and an increased heart rate. It is important to remain calm and contact a healthcare professional or poison control center for guidance. They can provide specific instructions based on the amount ingested and the individual's health status. Quick action and seeking medical advice are crucial steps in managing an overdose effectively.

In the case of a missed dose of Ebastine 5mg/5ml Syrup/Suspension, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare provider for guidance on how to get back on track with your medication regimen.

To administer Ebastine 5mg/5ml Syrup/Suspension, shake the bottle vigorously to ensure a uniform mixture, then use a measuring device like a marked measuring spoon or oral syringe to accurately measure the prescribed dose, which should be taken once daily, either with or without food, following the dosage instructions provided by your healthcare professional or as indicated on the medication packaging.

Here are the conditions or situations when Ebastine 5mg/5ml Syrup/Suspension should not be used:

• Do not use in patients with a known allergy or hypersensitivity to Ebastine or any of its excipients.
• Contraindicated in patients with a history of serious cardiovascular diseases, including but not limited to, unstable angina, recent myocardial infarction, or cardiac arrhythmias.
• Not suitable for patients with severe liver impairment or liver disease.
• Avoid in patients with a history of kidney disease or those currently experiencing kidney impairment.
• Should not be used in patients with a history of seizures or epilepsy.
• Contraindicated during pregnancy or breastfeeding.
• Not recommended for children below 6 years of age due to potential side effects.
• Do not administer to patients with a history of porphyria.
• Avoid in patients with a history of lung diseases such as asthma or chronic obstructive pulmonary disease (COPD).

The side effects of Ebastine 5mg/5ml Syrup/Suspension may include:

• Drowsiness or sedation
• Headache
• Dry mouth
• Fatigue or tiredness
• Dizziness
• Gastrointestinal disturbances (e.g., nausea, stomach pain)
• Increased appetite and weight gain
• Skin rashes or allergic reactions

Following are the precautions and warnings for Ebastine 5mg/5ml Syrup/Suspension:

• Do not use if you are allergic to Ebastine or any of the excipients in the syrup.
• This medication may cause drowsiness or dizziness, so patients should avoid driving or operating heavy machinery until they know how the medicine affects them.
• Caution is advised for patients with liver or kidney problems, as the dosage may need adjustment.
• Inform your doctor if you have a history of epilepsy or other seizure disorders before taking this medication.
• Ebastine should be used with caution in elderly patients as they may be more sensitive to its effects.
• Do not exceed the recommended dosage, as it may lead to serious adverse effects.
• If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medication.

Following are the drug interactions for Ebastine 5mg/5ml Syrup/Suspension:

• Alcohol may enhance the sedative effects of Ebastine, leading to increased drowsiness and impaired motor skills.
• Concomitant use with other antihistamines or CNS depressants (e.g., opioids, benzodiazepines) can result in additive sedation and respiratory depression.
• Ebastine may increase the blood levels of certain antifungal medications like ketoconazole and itraconazole, potentially leading to increased side effects.
• The effectiveness of Ebastine may be reduced when taken with antacids containing aluminum or magnesium.
• Caution is advised when combining Ebastine with erythromycin, as it may increase Ebastine's concentration in the body, leading to increased side effects.
• Ebastine should be used with caution in patients taking beta-blockers, as it may increase the risk of cardiovascular adverse effects.
• Drugs that induce certain liver enzymes (e.g., carbamazepine, phenytoin) may decrease Ebastine's effectiveness by increasing its metabolism.

Following are the food interactions for Ebastine 5mg/5ml Syrup/Suspension:

• Avoid consuming grapefruit or grapefruit juice as it may interfere with the metabolism of Ebastine, leading to increased drug levels in the body and potential side effects.
• Alcohol consumption should be limited or avoided as it can enhance the sedative effects of Ebastine, causing increased drowsiness and reduced alertness.
• Caffeine intake should be monitored as Ebastine may enhance its effects, potentially causing increased nervousness or insomnia.
• Fatty or high-fat meals may slightly delay the absorption of Ebastine, but this does not significantly affect its overall effectiveness.
• Avoid eating large quantities of citrus fruits like oranges or lemons right after taking the medication, as it may slightly reduce absorption.
• There is no specific food restriction, but maintaining a balanced diet is advisable for overall health.
• Always consult your healthcare provider for personalized advice regarding food interactions and medication management.
• Ensure you follow the prescribed dosage and duration of Ebastine treatment for optimal results.

Ebastine 5mg/5ml Syrup/Suspension should be stored in a secure and controlled environment, preferably in a locked cabinet or a designated storage area. Maintain a consistent room temperature, avoiding exposure to direct sunlight, excessive heat, or moisture to ensure the medication's integrity. Keep the syrup in its original container, tightly sealed, to prevent contamination and maintain its effectiveness. It is crucial not to store it in the bathroom or kitchen, as temperature fluctuations can impact its quality. Always verify the expiration date, and if the syrup is no longer required or has expired, proper disposal is essential. Do not dispose of it in sinks or toilets; instead, follow local guidelines or consult a pharmacist for safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Ebastine 5mg/5ml Syrup/Suspension:

• Ensure you take the medication as directed by your doctor or pharmacist.
• Before each use, shake the bottle vigorously to mix the contents thoroughly.
• Administer the syrup with a glass of water; avoid tea, coffee, or dairy products for better absorption.
• Maintain a consistent routine by taking your dose at the same time daily.
• If stomach irritation occurs, consider taking the syrup with food or post-meals.
• Store the syrup in a secure location, out of the reach of children.
• Always check the expiration date, and do not use if it's expired.