Labetalol (100mg) 20 Tablets

Labetalol HCl, the active ingredient in the 100mg tablet, acts as a dual blocker of both alpha and beta-adrenergic receptors. It primarily exhibits its effects by competing with catecholamines, such as epinephrine and norepinephrine, for binding sites on these receptors. By blocking alpha-1 receptors, labetalol causes vasodilation, leading to a reduction in peripheral vascular resistance and decreased blood pressure. Simultaneously, its beta-blockade properties reduce cardiac output by decreasing heart rate and myocardial contractility, further contributing to blood pressure control. This dual mechanism of action makes labetalol effective in managing hypertension and related cardiovascular conditions.

Labetalol HCl 100mg

Beta-blocker.

Tablet

The following are the uses of Labetalol HCl 100mg Tablet:

• Used for treating high blood pressure, ensuring effective control and management.
• Used for stabilizing heart rhythm irregularities, helping to regulate heartbeat.
• Used for managing chest pain associated with heart conditions, providing relief and comfort.
• Used for preventing potential heart issues after a heart attack, offering protection and support.
• Used for reducing the risk of future cardiovascular events, promoting long-term heart health.
• Used for managing hypertension during pregnancy, ensuring safety for both mother and child.
• Used for controlling blood pressure in various medical conditions, offering tailored treatment.
• Used for supporting overall cardiovascular health and function, contributing to a healthier heart.

In the case of an overdose of Labetalol HCl 100mg Tablets, it is important to recognize the potential severity of the situation. Overdose symptoms may include dizziness, fainting, and a significant drop in blood pressure. If an overdose is suspected, seek medical advice promptly. Treatment may involve supportive care, monitoring vital signs, and managing symptoms until the medication's effects wear off. Quick action can help mitigate the risks associated with an overdose of this medication.

In the case of a missed dose of Labetalol HCl 100mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen. Consult your healthcare provider if you have any concerns or questions regarding missed doses.

To take Labetalol HCl 100mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional.

Following are the conditions/situations when Labetalol HCl 100mg Tablet should not be used:

• Should not be used in patients with a known allergy or hypersensitivity to Labetalol or any other beta-blockers.
• Contraindicated in patients with severe bradycardia (very slow heart rate).
• Not suitable for individuals with cardiogenic shock, a condition where the heart cannot pump enough blood to meet the body's needs.
• Should not be used in patients with severe heart failure or those who have recently experienced a heart attack and have a low ejection fraction.
• Contraindicated in patients with severe liver disease or liver cirrhosis.
• Should not be used in individuals with severe asthma or chronic obstructive pulmonary disease (COPD) as it can worsen breathing problems.
• Not recommended for patients with a history of bronchospasm (narrowing of the airways).
• Should be avoided in patients with Raynaud's syndrome, a condition affecting blood vessels in the fingers and toes.
• Contraindicated in patients with untreated pheochromocytoma, a rare tumor of the adrenal gland.

The side effects of Labetalol HCl 100mg Tablet may include:

• Fatigue and weakness
• Dizziness or lightheadedness
• Gastrointestinal issues like nausea, vomiting, or diarrhea
• Dry mouth
• Headaches
• Sleep disturbances, including insomnia or vivid dreams
• Decreased heart rate (bradycardia)
• Sexual dysfunction

Following are the precautions and warnings for Labetalol HCl 100mg Tablet:

• This medication should not be taken by individuals with a known allergy to Labetalol or any of its ingredients.
• Patients with a history of liver or kidney disease should exercise caution and inform their doctor, as dose adjustments may be necessary.
• Labetalol may cause dizziness or lightheadedness; patients should stand up slowly to avoid falls, especially when first starting the medication.
• It is important to monitor blood pressure regularly while taking this medication, and inform your doctor if you experience chest pain, rapid heartbeat, or difficulty breathing.
• Patients with diabetes should be cautious as Labetalol may mask the symptoms of low blood sugar.
• Elderly patients may be more sensitive to the effects of this medication and should be monitored closely.
• Pregnant or breastfeeding women should consult their doctor before taking Labetalol, as it may have potential risks for the fetus or infant.

Following are the drug interactions for Labetalol HCl 100mg Tablet:

• Concurrent use with other antihypertensive medications (e.g., ACE inhibitors, diuretics) can result in additive blood pressure-lowering effects.
• Labetalol may increase the plasma concentrations of lidocaine and propranolol, requiring dosage adjustments.
• Concomitant use with calcium channel blockers can lead to enhanced hypotensive and negative inotropic effects.
• The use of nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce the antihypertensive effect of Labetalol.
• Labetalol can mask the early warning symptoms of hypoglycemia in diabetic patients, especially when used with insulin or oral hypoglycemic agents.
• Caution is advised when combining with digoxin, as it may increase serum digoxin levels.
• It can increase the risk of bradycardia and heart block when used with other beta-blockers or cardiac glycosides.

Following are the food interactions to consider with Labetalol HCl 100mg Tablet:

• Avoid consuming large amounts of grapefruits or grapefruit juice as it may interfere with the drug's metabolism, potentially increasing the levels of Labetalol in the body.
• Limit alcohol consumption as it may lower your blood pressure further and increase the risk of dizziness or lightheadedness.
• Caffeinated beverages like coffee, tea, or energy drinks should be consumed in moderation as they can counteract the blood pressure-lowering effect of Labetalol.
• A high-sodium diet can reduce the effectiveness of Labetalol, so limit salty foods and processed snacks.
• Potassium-rich foods like bananas, oranges, and spinach are beneficial as Labetalol may cause potassium loss.
• Consume a balanced diet with whole grains, lean proteins, and healthy fats to support overall cardiovascular health.
• Avoid energy drinks or high-sugar beverages as they may affect blood pressure and interact with the medication's effectiveness.
• Always follow the dietary recommendations provided by your healthcare professional for optimal results.

Labetalol HCl 100mg Tablets should be stored in a cool, controlled environment, ideally between 68°F and 77°F (20°C and 25°C), with brief excursions permitted between 59°F and 86°F (15°C and 30°C). Protect the tablets from light and moisture by keeping them in their original, tightly sealed container. It is crucial to store this medication away from children and pets to prevent accidental ingestion. Always check the expiration date, and do not use the tablets if they are expired. For disposal, do not throw the medication in the trash or flush it down the toilet; instead, follow local guidelines for pharmaceutical waste disposal or consult a healthcare professional for advice on safe disposal methods. Proper storage and disposal practices ensure the integrity of the medication and contribute to environmental responsibility.

Following are the quick tips for Labetalol HCl 100mg Tablet:

• Consult your doctor before starting this medication and provide a detailed medical history.
• Take the tablet as directed by your doctor, typically 2-3 times a day.
• Swallow the tablet whole with a full glass of water, do not crush or chew.
• Take it at evenly spaced intervals to maintain a consistent level in your body.
• Do not suddenly stop taking this medicine without consulting your doctor.
• Inform your doctor if you have pre-existing kidney or liver disease.
• Store the tablets in a cool, dry place, away from direct sunlight.