Lazma (0.01/4/0.05%) 30g Cream

Fluocinolone, Hydroquinone, and Tretinoin Cream work synergistically to address various skin concerns. Fluocinolone acetonide, a potent synthetic corticosteroid, exerts anti-inflammatory and immunosuppressive effects by inhibiting the production of pro-inflammatory mediators and reducing the activity of immune cells. Hydroquinone, a depigmenting agent, inhibits melanin production by decreasing the activity of tyrosinase, a key enzyme in melanin synthesis, thus lightening areas of hyperpigmentation. Tretinoin, a derivative of vitamin A, promotes cell turnover by binding to retinoic acid receptors, stimulating cellular regeneration, and enhancing collagen production, which can improve skin texture and reduce fine lines. Together, these components work to suppress inflammation, reduce hyperpigmentation, and enhance skin renewal, making the cream effective for treating various dermatological conditions.

Fluocinolone, Hydroquinone, Tretinoin

Corticosteroid, Antioxidant, Retinoid.

Cream

The following are the uses of Fluocinolone, Hydroquinone, Tretinoin Cream:

• Used for treating melasma, a skin condition characterized by dark patches on the face.
• Used to reduce skin discoloration and even out skin tone.
• Used to suppress inflammation and reduce redness associated with melasma.
• Used to exfoliate the skin, removing the outer layer of dead skin cells and promoting the growth of new cells.
• Used to inhibit the production of melanin, addressing the overproduction that causes dark spots.
• Used to improve the overall appearance of the skin, making it brighter and more even-toned.
• Used to prevent the recurrence of melasma by maintaining skin health and reducing triggers.
• Used to complement other skin treatments, such as sunscreen and protective clothing, for comprehensive melasma management.

Apply a thin layer to the affected area(s) once a day, at least 30 minutes before bedtime

In the case of an overdose of Fluocinolone, Hydroquinone, and Tretinoin Cream, the severity of symptoms may vary. Topical application of excessive amounts can lead to local skin reactions such as redness, peeling, or irritation. However, significant systemic effects are unlikely due to the low absorption of these medications through the skin. If ingested orally in large quantities, gastrointestinal symptoms like nausea, vomiting, or abdominal pain may occur. It is advisable to contact a healthcare professional for guidance and monitoring in any suspected overdose situation.

In the case of a missed dose of Fluocinolone, Hydroquinone, and Tretinoin Cream, it is generally recommended to apply the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, consult your healthcare provider for guidance, as they may advise you to restart the medication or provide specific instructions to ensure the treatment's effectiveness.

To use Fluocinolone, Hydroquinone, and Tretinoin Cream, clean and dry the affected area, apply a thin layer of the cream once daily, preferably in the evening, and gently rub it into the skin, following the instructions provided by your healthcare provider or dermatologist.

Following are the conditions/situations when Fluocinolone, Hydroquinone, Tretinoin Cream should not be used:

• Should not be used on individuals with a known allergy to any of the active ingredients Fluocinolone, Hydroquinone, or Tretinoin, or any of the cream's components.
• Not suitable for individuals with certain skin conditions like eczema, psoriasis, or severe acne, as it may aggravate these conditions.
• Contraindicated in individuals with skin infections or open wounds in the area of application.
• Avoid using on skin that is sunburned, windburned, dry, chapped, irritated, or inflamed.
• Should not be used on skin that is affected by perioral dermatitis.
• Not recommended for individuals who have recently had a facial peel, laser treatment, or any other skin procedure.
• Avoid using on skin that is highly sensitive or thin, such as the skin around the eyes, mouth, or nose.
• Do not use this cream for conditions it is not prescribed for, such as long-term use on large areas of the body.
• Discontinue use and consult a doctor if there is no improvement or if the condition worsens after a few weeks of treatment.

The side effects of Fluocinolone, Hydroquinone, Tretinoin Cream may include:

• Burning or stinging sensation at the application site
• Dryness or peeling of the skin
• Redness or irritation
• Itching or rash
• Thinning of the skin
• Changes in skin color (lightening or darkening)
• Increased sensitivity to sunlight

Following are the precautions and warnings for Fluocinolone, Hydroquinone, Tretinoin Cream:

• Do not use if you are allergic to any of the ingredients, including fluocinolone, hydroquinone, or tretinoin.
• This medication is for external use only and should not be applied near the eyes, mouth, or open wounds.
• Avoid sun exposure and use sunscreen when going outdoors, as this medication may increase skin sensitivity to sunlight.
• Do not use this cream for prolonged periods without consulting a doctor, as it may cause skin thinning or other long-term effects.
• It is important to use this medication exactly as prescribed and not to exceed the recommended dosage or frequency.
• Pregnant or breastfeeding women should consult their doctor before using this cream, as the risks and benefits should be carefully evaluated.
• Keep out of reach of children and pets. Store in a cool, dry place away from direct sunlight.

Following are the drug interactions for Fluocinolone, Hydroquinone, and Tretinoin Cream:

• It may increase the absorption of other topical medications, leading to potential adverse effects.
• Tretinoin can increase sensitivity to sunlight, so avoid using other medications that cause photosensitivity.
• Fluocinolone is a corticosteroid, and its effects may be reduced by certain drugs like rifampin, phenytoin, and carbamazepine.
• Combining with other topical corticosteroids or retinoids may increase the risk of skin irritation and thinning.
• Avoid using other skin-irritating products like astringents, exfoliants, or harsh soaps.
• The effectiveness of hydroquinone may be reduced by antioxidants like vitamin C or E when applied simultaneously.
• Topical antibiotics, such as clindamycin or erythromycin, can be used with caution but may increase skin dryness.

Following are the food interactions for Fluocinolone, Hydroquinone, Tretinoin Cream:

• Avoid excessive sun exposure and use sunscreen regularly to minimize UV damage. UV rays can interact with the cream's active ingredients.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of the drugs in the liver, potentially altering their effectiveness.
• Avoid alcohol-based skincare products as they can cause irritation, especially when used with Tretinoin.
• Dairy products and foods rich in Vitamin A should be consumed in moderation as excessive Vitamin A intake can lead to Vitamin A toxicity when combined with Tretinoin.
• Fatty or oily foods may increase the absorption of Fluocinolone, potentially increasing its side effects.
• Hydroquinone may interact with certain foods containing high levels of antioxidants, affecting its skin-lightening properties.
• Always consult a dermatologist for personalized advice on dietary considerations while using this medication.
• Maintain a balanced diet to support overall skin health during treatment.

Fluocinolone, Hydroquinone, Tretinoin Cream should be stored in a cool, dry location, preferably at room temperature, and protected from direct sunlight. It is crucial to keep the cream in its original packaging, ensuring the container remains tightly sealed to maintain its integrity and prevent contamination. Avoid exposing the cream to extreme temperatures, such as those found near heat sources or in the bathroom, as this can compromise its effectiveness. Always check the expiration date before use, and dispose of any expired or unused cream responsibly. Do not flush or pour it down the drain; instead, consult a pharmacist or healthcare professional for appropriate disposal methods. Keep the cream out of children's reach to prevent accidental contact or ingestion.

No

Following are the quick tips for Fluocinolone, Hydroquinone, Tretinoin Cream:

• Clean and dry the affected area before applying the cream.
• Use a pea-sized amount of cream for each application.
• Gently rub the cream into the skin until it is evenly spread.
• Apply the cream once daily, preferably at bedtime, or as directed by your doctor.
• Avoid applying the cream near the eyes, mouth, or open wounds.
• Wash your hands after application to avoid accidental contact with sensitive areas.
• Store the cream at room temperature, away from sunlight and moisture.