Mefnac (50mg/5ml) 60ml Syrup

Mefenamic acid, a non-steroidal anti-inflammatory drug (NSAID), exerts its mechanism of action by inhibiting the cyclooxygenase (COX) enzymes, primarily COX-1 and COX-2. These enzymes play a crucial role in the synthesis of prostaglandins, which are involved in mediating inflammation and pain. By blocking the action of COX enzymes, mefenamic acid reduces the production of prostaglandins, resulting in decreased inflammation, pain relief, and reduction of fever. Specifically, it prevents the conversion of arachidonic acid to prostaglandin H2, a precursor to various prostaglandins and thromboxanes. This inhibition occurs at the site of inflammation, where mefenamic acid exerts its therapeutic effects, making it effective in managing mild to moderate pain and inflammatory conditions.

Nonsteroidal anti-inflammatory drug (NSAID)

Suspension

The following are the uses of Mefenamic Acid 50mg Syrup/Suspension:

• Used for relieving period pain and discomfort.
• Used for reducing inflammation and fever.
• Used for managing mild to moderate pain, such as headaches, toothaches, and post-operative pain.
• Used for treating menstrual symptoms like cramps and heavy bleeding.
• Used for easing muscle and joint pain caused by mild arthritis or injury.
• Used for bringing relief to pain and swelling in conditions like back pain or sprains.
• Used for controlling pain and inflammation in certain medical procedures.

Follow these dosage instructions:

• Take as per doctor's Prescription.
• Take one tablespoon of the syrup daily as your doctor suggests.
• Your doctor will determine the treatment length based on your symptom severity.

In the case of an overdose of Mefenamic Acid 50mg Syrup/Suspension, individuals may experience symptoms such as nausea, vomiting, abdominal pain, and in severe cases, gastrointestinal bleeding. It is important to seek medical advice promptly if an overdose is suspected. The treatment for an overdose may involve managing symptoms and providing supportive care. Quick action can help ensure the best possible outcome and prevent potential complications.

In the case of a missed dose of Mefenamic Acid 50mg Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you have missed multiple doses, contact your healthcare provider for guidance on how to safely resume your medication. It is essential to maintain a consistent dosing routine for the best therapeutic effect.

To administer Mefenamic Acid 50mg Syrup/Suspension, shake the bottle thoroughly, measure the prescribed dose with an accurate measuring device like a syringe, and administer it orally, following the dosage instructions provided by your healthcare professional, typically taken 3-4 times a day with food and a full glass of water.

Situations and conditions where Mefenamic Acid 50mg Syrup/Suspension is contraindicated:

• Do not use if you have a known allergy or hypersensitivity to Mefenamic Acid or any non-steroidal anti-inflammatory drugs (NSAIDs).
• Contraindicated in patients with severe kidney or liver impairment.
• Should not be used in individuals with a history of gastrointestinal bleeding or perforation.
• Not suitable for patients who have recently undergone coronary artery bypass graft (CABG) surgery.
• Avoid if you have uncontrolled hypertension (high blood pressure).
• Do not administer to patients with a history of asthma or allergic reactions triggered by aspirin or other NSAIDs.
• Contraindicated during the third trimester of pregnancy.

The side effects of Mefenamic Acid 50mg Syrup/Suspension may include:

• Nausea and vomiting
• Diarrhea or constipation
• Stomach pain or cramps
• Dizziness or drowsiness
• Headache
• Skin rashes or itching
• Ringing in the ears (tinnitus)
• Increased blood pressure

Following are the precautions and warnings for Mefenamic Acid 50mg Syrup/Suspension:

• Avoid using this medication if you have a known allergy to Mefenamic Acid or any other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
• Patients with a history of gastrointestinal bleeding, ulcers, or other stomach disorders should use with caution and under medical supervision.
• Not recommended for individuals with severe heart, liver, or kidney disease without medical advice.
• Mefenamic Acid may increase the risk of blood clots, heart attack, or stroke, especially in long-term use; consult your doctor about the risks.
• Avoid alcohol consumption while taking this medication as it may increase the risk of stomach bleeding.
• This medication may cause dizziness or drowsiness. Do not drive or operate heavy machinery until you know how it affects you.
• Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding before using this medication.

Following are the drug interactions for Mefenamic Acid 50mg Syrup/Suspension:

• May reduce the effectiveness of oral contraceptives, so alternative contraception is recommended.
• Can increase the risk of bleeding when taken with anticoagulants like warfarin, requiring close monitoring.
• The risk of gastrointestinal bleeding and ulceration is higher when combined with corticosteroids or other non-steroidal anti-inflammatory drugs (NSAIDs).
• Potentially increases plasma levels of lithium, requiring close monitoring for lithium toxicity.
• May reduce the efficacy of angiotensin-converting enzyme (ACE) inhibitors, potentially affecting blood pressure control.
• Mefenamic acid can decrease the diuretic effect of furosemide and thiazides, requiring dose adjustments.
• Caution is advised when using with other drugs that increase the risk of nephrotoxicity, as it may further impact kidney function.

Following are the food interactions for Mefenamic Acid 50mg Syrup/Suspension:

• Avoid excessive alcohol consumption while taking this medication as it may increase the risk of gastrointestinal bleeding and liver toxicity.
• Grapefruit and grapefruit juice should be consumed with caution as they can inhibit the metabolism of Mefenamic Acid, leading to increased drug levels in the body and potentially enhancing side effects.
• Avoid high-fat meals as they may delay the absorption of Mefenamic Acid, reducing its effectiveness.
• Dairy products like milk and cheese may interfere with the absorption of Mefenamic Acid, leading to reduced effectiveness.
• Avoid spicy foods as they can irritate the stomach and exacerbate gastrointestinal side effects associated with Mefenamic Acid.
• Caffeine-rich beverages like coffee and energy drinks may increase the risk of nervousness, insomnia, and heart palpitations when taken with Mefenamic Acid.
• Consuming large amounts of green leafy vegetables rich in vitamin K (e.g., spinach, kale) may reduce the anticoagulant effect of Mefenamic Acid if used for this purpose.

Mefenamic Acid 50mg Syrup/Suspension should be stored in a cool, dry area, maintaining room temperature, and shielded from direct sunlight and moisture. Keep the medication securely sealed in its original packaging to prevent contamination. Avoid storage in bathrooms or near heat-emitting appliances like stoves or radiators, as temperature fluctuations can compromise the medication's integrity. Prior to use, verify the expiration date on the packaging, and responsibly dispose of any unused or expired syrup; refrain from flushing it down the toilet or pouring it into drains. Consult your pharmacist or healthcare professional for appropriate disposal methods. Ensure the medication is inaccessible to children to prevent accidental ingestion.

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Following are the quick tips for Mefenamic Acid 50mg Syrup/Suspension:

• Consult a doctor for proper dosage and duration based on your medical condition.
• Administer the prescribed dose accurately using the measuring cup provided.
• Ensure the syrup is well shaken before each use to maintain consistency.
• Take the syrup with a full glass of water to aid in swallowing.
• Maintain a consistent schedule for taking the medication for better effectiveness.
• Avoid missing doses; if you miss one, consult your doctor or pharmacist for advice.
• Store the syrup at room temperature, away from direct sunlight and moisture.
• Keep the medication out of children's reach to prevent accidental consumption.