Mirabet (25mg) 20 Tablets

Mirabegron is a beta-3 adrenergic receptor agonist, used to treat symptoms of overactive bladder, such as frequent urination and urinary urgency. Mirabegron works by relaxing the bladder muscles by activating these beta-3 adrenergic receptors. It is absorbed from the gastrointestinal tract, reaching peak concentrations in the blood within an hour. It is then metabolized by the liver and excreted in the urine, with an approximate half-life of 9-10 hours.

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Beta-3 Adrenergic Agonist

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Tablet

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Unveiling its multifaceted uses and transformative applications as follows:

• Treating symptoms of overactive bladder, such as frequent urination, urgency, and leakage.
• Improving urinary incontinence (loss of bladder control) in adults who've been treated with medicine that didn't work well or caused side effects.
• Helping to reduce the number of trips to the bathroom at night.

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Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Hypertension- Take 1 tablet of Mirabegron 25mg once or twice a day, preferably with food.
• Overactive Bladder- Take 1 tablet of Mirabegron 25mg once a day, preferably with food.

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In the case of an overdose of Mirabegron, the first step is to ensure the patient's survival through supportive measures. This may involve making sure the patient can breathe properly and their blood is circulating well, and that the overdosed medication, as well as other drugs taken, can be absorbed into their system. Alongside these measures, it may also be necessary to empty the patient's stomach through pumping, however, it is vital to seek immediate medical attention as overdose symptoms can be severe and fatal, and quicker intervention may be crucial for recovery. Is there anything else I can do to help with this message?

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If you have missed a does of Mirabegron 25mg, there is no need to worry. The first step is to take the missed dose as soon as possible. However, if it is already time for your next scheduled dose, it is best to skip the missed dose altogether. It is not advisable to double up on doses to make up for the missed one as it may result in an overdose or adverse effects. It is important to follow the specific dosing instructions provided by your physician or pharmacist and to only take the amount prescribed. If you have any questions or concerns about missing a dose, it is best to consult with your physician or pharmacist directly for personalized guidance and advice. They can provide further instructions and help you understand how to proceed based on your medical history and the dosing schedule.

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Before starting Mirabegron 25mg, ensure you read the medication guide provided by your pharmacist. This medication is typically taken once daily, usually for up to 8 weeks with a dosage increase every week. Take the medication whole and ensure you do not crush or chew it as this can cause it to release faster, leading to more side effects. If you experience any allergic reaction symptoms such as difficulty breathing, swallowing, speaking differently, changes in eye contact, skin rash, itching, bruising, or chest pain, seek medical help immediately. Before taking the medication, inform your doctor if you have a history of heart disease, high blood pressure, stroke, blood circulation problems, kidney disease, ulcerative colitis or Crohn's disease, or glaucoma. This medication is not recommended for pregnant or breastfeeding women, as it may pose a risk to the unborn baby. This medication may cause dizziness, so it is recommended to avoid driving or operating heavy machinery. Alcohol consumption is not recommended as it may worsen the side effects of this medication. If you miss a dose, take it as soon as possible. If it is near the next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up on the dose to catch up. Store the medication in a cool, dry place, away from direct light and heat. Keep the medication at room temperature, preferably between 68-77 degrees F (20-25 degrees C). If you have any further questions or concerns about using Mirabegron 25mg, consult with your doctor or pharmacist.

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Discerning instances where this medication may not be appropriate:

• Hypersensitivity (allergic reaction) to Mirabegron or any of the other ingredients in the formulation.
• If you have asthma or other breathing problems. Mirabegron may increase the risk of asthma attacks.
• An enlarged prostate (benign prostatic hyperplasia)
• Urination problems or bladder surgery within the last six months.
• History of mental illness, including depression, anxiety, or thoughts of suicide.

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Unraveling the side effects lurking behind this medications are as follows:

• Heartburn
• Difficulty swallowing
• Nausea
• Stomach Pain
• Constipation
• Dizziness
• Fatigue
• Blurred Vision
• Headache
• Confusion
• Hallucination
• Tremors
• Joint Pain
• Muscle Pain
• Breast Tenderness
• Menstrual Changes
• Itching
• Rash
• Dry Mouth
• Stuffy or Runny Nose
• Sneezing
• Back Pain
• Loss of Appetite
• Weight Gain
• Depression
• Anxiety
• Insomnia
• Irritability
• Agitation
• Panic Attacks
• Restlessness
• Suicidal Thoughts or Behavior
• Angina (Chest Pain)
• Palpitations (Rapid, Fluttering Feeling in the Chest)
• Tachycardia (Increased Heart Rate)
• Hypotension (Low Blood Pressure)
• Syncope (Fainting)
• Erectile Dysfunction
• Galactorrhea (Increased Milk Secretion from the Breasts)
• Gynecomastia (Enlargement of the Breasts in Males)
• Nausea and Vomiting

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When considering this medication, it's important to observe the following precautions and warnings:

• Patients with controlled and less severe hypertension, or a history of QT prolongation should be cautious, as the medication may impact cardiac function or exacerbate these conditions.
• Individuals with clinically significant bladder outlet obstruction, benign prostatic hyperplasia, or a history of post-void residual (PVR) volume greater than 200 mL should use this medication carefully, as it may affect urinary function.
• Those receiving antimuscarinic agents for overactive bladder or other drugs known to prolong the QT interval should be monitored closely to avoid potential drug interactions and complications.
• Patients with renal or hepatic impairment who are also taking strong CYP3A inhibitors should exercise caution, as these factors can influence the medication’s effectiveness and safety.
• The medication may not be suitable for children, pregnant or lactating individuals, so consultation with a healthcare provider is essential before use in these populations.

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Drug interactions with mirabegron include:

• CYP3A4 inhibitors (e.g., ketoconazole) (may increase mirabegron levels)
• CYP3A4 inducers (e.g., rifampin) (may decrease mirabegron levels)
• Antimuscarinics (e.g., oxybutynin) (may have additive effects on bladder function)
• Beta-blockers (e.g., propranolol) (may counteract the effects of mirabegron)
• Diuretics (e.g., furosemide) (may increase risk of urinary tract-related side effects)
• Other medications affecting bladder function (e.g., desmopressin) (may have additive effects)

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Store mirabegron at room temperature, away from moisture and heat. Keep the medication in its original packaging, tightly sealed, and out of reach of children and pets. For disposal, do not flush it down the toilet or pour it into drains unless instructed. Instead, follow local regulations for medication disposal or use a take-back program if available. Always discard expired or unused medication responsibly to prevent accidental use or harm.

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