Mosegor 30 Tablets

Pizotifen's primary mechanism of action is believed to be its ability to block serotonin (5-HT) receptors, particularly the 5-HT2 receptors, in both the central and peripheral nervous systems. By antagonizing these receptors, pizotifen inhibits serotonin-mediated vasodilation and reduces the release of other vasoactive substances, such as histamine and kinins. This action helps to prevent the dilation of blood vessels, which is a key factor in migraine and other types of headaches. Additionally, pizotifen may also have an effect on serotonin-mediated neuronal pathways involved in pain transmission, thereby contributing to its efficacy in managing migraine and related conditions.

Serotonin antagonist antihistamine.

Tablet

The following are the uses of Pizotifen Tablet:

• Used for preventing migraine headaches.
• Used to reduce the frequency and severity of migraine attacks.
• Used to manage symptoms like nausea and light sensitivity associated with migraines.
• Used to treat cluster headaches and their associated symptoms.
• Used to prevent vascular headaches and reduce their occurrence.
• Used for its anti-serotonin and antihistamine properties to alleviate headache pain.
• Used as a long-term preventive measure for chronic migraine sufferers.

To be taken as per doctor's prescription

In the case of an overdose of Pizotifen Tablets, it is important to recognize the signs and act swiftly. Overdose symptoms may include severe drowsiness, restlessness, and confusion. If you suspect an overdose, seek medical advice immediately. Quick action can prevent serious health risks and potential complications. It is crucial to keep medications out of reach of children to prevent accidental ingestion and overdose.

In the case of a missed dose of Pizotifen Tablet, it is important to take the dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one. Never double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss several doses, consult your healthcare professional for advice on how to safely resume the medication and adjust the dosing schedule. It is recommended to establish a routine to help you remember to take your medication at the same time each day to avoid missing doses.

To take Pizotifen tablets, place the tablet in your mouth and swallow it whole with a glass of water, preferably at bedtime or as directed by your healthcare professional, following the prescribed dosage and duration as instructed.

Following are the conditions when Pizotifen Tablet should be avoided or used with caution:

• Not suitable for individuals with a known allergy to Pizotifen or other piperazine derivatives.
• Should not be used in patients with severe liver or kidney impairment.
• Contraindicated in individuals with a history of heart attack or severe cardiovascular disease.
• Not recommended for people with a history of gastrointestinal obstruction or severe constipation.
• Avoid using in patients with narrow-angle glaucoma or untreated open-angle glaucoma.
• Not suitable for individuals with a history of epilepsy or seizures.
• Should be used with caution in patients with a history of depression or suicidal thoughts.
• Avoid using Pizotifen in patients with severe hypertension (high blood pressure).
• Not recommended for individuals with a history of severe respiratory conditions, such as asthma or chronic obstructive pulmonary disease (COPD).

The side effects of Pizotifen Tablet may include:

• Drowsiness or sedation
• Weight gain
• Dry mouth
• Dizziness
• Fatigue and weakness
• Nausea and gastrointestinal discomfort
• Headaches
• Skin rashes or itching

Following are the precautions and warnings for Pizotifen Tablet:

• Allergic reactions may occur; individuals with a known hypersensitivity to Pizotifen or related compounds should avoid its use.
• Not recommended for patients with a history of epilepsy or those prone to seizures, as it may lower the seizure threshold.
• May cause drowsiness and dizziness; patients should avoid driving, operating heavy machinery, or engaging in activities requiring mental alertness until they know how the medication affects them.
• Alcohol consumption should be avoided as it can enhance the sedative effects of the medication.
• Patients with a history of liver or kidney disease should exercise caution and consult a doctor, as dosage adjustments might be necessary.
• Not recommended for children under 6 years of age unless advised by a healthcare professional.
• Pregnant and breastfeeding women should consult their doctor before taking Pizotifen, as it may have potential risks to the fetus or infant.

Following are the drug interactions for Pizotifen Tablet:

• Pizotifen can enhance the effects of CNS depressants like alcohol, opioids, and benzodiazepines, leading to increased sedation and impaired coordination.
• It may interact with other antihistamines, increasing the risk of drowsiness and reducing alertness.
• MAO inhibitors should be avoided during treatment with Pizotifen due to the potential for severe reactions, including elevated blood pressure.
• Concomitant use with other serotonin-affecting medications (e.g., SSRIs, SNRIs) may lead to serotonin syndrome, characterized by agitation, confusion, and gastrointestinal symptoms.
• Pizotifen can increase the effects of anticoagulants, necessitating close monitoring for bleeding complications.
• The effectiveness of certain anti-hypertensive medications may be reduced by Pizotifen, requiring careful blood pressure monitoring.
• Caution is advised when combining Pizotifen with medications metabolized by the liver, as it may alter their metabolism and affect drug levels in the body.

Following are the food interactions to be aware of when taking Pizotifen Tablets:

• Avoid consuming alcohol during the treatment, as it may increase the sedative effects and cause excessive drowsiness.
• Grapefruit and grapefruit juice should be consumed with caution as they can inhibit the metabolism of Pizotifen, potentially leading to increased blood levels of the medication.
• Caffeine-rich beverages like coffee and tea might interact with Pizotifen, intensifying its sedative effects and causing sleepiness.
• Foods high in tyramine, such as aged cheeses, cured meats, and certain types of beer, should be avoided as they may interact with Pizotifen and lead to increased blood pressure.
• Chocolate contains a compound called phenylethylamine, which may interact with Pizotifen and potentially affect its effectiveness.
• Fatty meals can slow down the absorption of Pizotifen, leading to a delay in the onset of its effects.
• Certain spices and hot foods might increase the blood flow to the head and face, which could potentially counteract the effects of Pizotifen in reducing migraines.

Pizotifen Tablets should be stored in a secure and dry location, preferably in their original container, at room temperature, away from excessive heat, direct sunlight, and moisture. It is crucial to keep the tablets away from children and pets to prevent accidental ingestion. Do not store them in the bathroom or kitchen, as these areas may have varying temperatures and humidity levels that can impact the medication's quality. Always check the expiration date on the package, and if the tablets have expired or are no longer needed, do not flush them down the toilet or throw them into the trash. Instead, consult your pharmacist or local waste disposal company for guidance on safe and environmentally friendly disposal practices to ensure proper waste management.

No

Following are the quick tips for Pizotifen Tablet:

• Consult a doctor for the correct dosage and duration tailored to your medical condition.
• Take the tablet as a whole; do not crush, chew, or break it.
• Consume the tablet with a full glass of water for easier swallowing.
• Avoid consuming alcohol while taking this medication as it may intensify side effects.
• If you experience drowsiness, avoid driving or operating heavy machinery.
• Store the medication in a cool, dry place, away from direct sunlight and moisture.
• Do not share this medication with others, even if their symptoms seem similar.