Neo-Sedil (2.5mg/5ml) 90ml Syrup

Levocetirizine, the active ingredient in Levocetirizine Syrup/Suspension, is a second-generation antihistamine that selectively inhibits peripheral histamine H1 receptors. It works by blocking the action of histamine, a chemical released during allergic reactions, thereby reducing the symptoms associated with allergies. This medication primarily targets the H1 receptors in the nasal passages, respiratory tract, and other tissues, preventing histamine from binding to these receptors. By doing so, Levocetirizine effectively relieves allergic symptoms such as sneezing, itching, runny nose, and watery eyes, without causing significant drowsiness, which is a common side effect of older, first-generation antihistamines.

Levocetirizine

Antihistamine

Suspension

The following are the uses of Levocetirizine Syrup/Suspension:

• Used for relieving symptoms of seasonal allergies like sneezing, runny nose, and itching.
• Used for treating chronic hives and reducing skin inflammation.
• Used to alleviate symptoms of allergic rhinitis, making breathing easier.
• Used for managing allergy-induced nasal congestion and eye irritation.
• Used to suppress allergic reactions and provide comfort during pollen seasons.
• Used to reduce the body's response to allergens, improving overall well-being.
• Used for controlling itching and discomfort caused by various allergies.

In the case of an overdose of Levocetiririzine Syrup/Suspension, the severity of symptoms can vary depending on the amount ingested. Common symptoms may include excessive drowsiness, rapid heartbeat, and confusion. In more severe cases, seizures, respiratory depression, and even loss of consciousness may occur. Prompt medical attention is necessary, and healthcare professionals should be informed about the specific amount ingested to provide appropriate treatment and support.

In the case of a missed dose of Levocetirizine Syrup/Suspension, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen.

To administer Levocetirizine Syrup/Suspension, shake the bottle vigorously, then measure the prescribed dose using an accurate measuring device like a marked measuring spoon or oral syringe, and take it orally once daily, with or without food, following the dosage instructions provided by your healthcare professional or as indicated on the medication label.

Following are the conditions/situations when Levocetirizine Syrup/Suspension should not be used:

• Not suitable for individuals with a known allergy to Levocetirizine or any other antihistamines.
• Should not be used in patients with a history of kidney disease or impaired kidney function.
• Contraindicated in patients with a history of long QT syndrome or other heart-related conditions.
• Not recommended for individuals with liver impairment or liver disease.
• Avoid using in patients with a history of seizures or epilepsy.
• Not suitable for children below 6 months of age.
• Should be used with caution in elderly patients, especially those with dementia or cognitive impairment.

The side effects of Levocetirizine Syrup/Suspension may include:

• Drowsiness or fatigue
• Dry mouth
• Headache
• Dizziness
• Nausea or stomach discomfort
• Diarrhea
• Sore throat
• Sleep disturbances

Following are the precautions and warnings for Levocetirizine Syrup/Suspension:

• Do not take if you are allergic to Levocetirizine or any other antihistamines.
• This medication may cause drowsiness, so avoid driving or operating heavy machinery until you know how it affects you.
• Alcohol consumption should be avoided as it can increase the risk of side effects.
• Patients with kidney problems should use with caution and consult a doctor, as dosage adjustments might be necessary.
• Elderly individuals may be more sensitive to the side effects, so regular monitoring is advised.
• Consult a doctor if you have a history of liver problems or are currently taking other medications.
• If symptoms persist or worsen after a few days of treatment, seek medical advice.

Following are the drug interactions for Levocetirizine Syrup/Suspension:

• Avoid co-administration with alcohol as it may increase the risk of central nervous system depression.
• Macrolide antibiotics (e.g., erythromycin) and ketoconazole can increase the concentration of levocetirizine, potentially leading to increased side effects.
• Anticonvulsants like carbamazepine and phenytoin may decrease the effectiveness of levocetirizine by increasing its metabolism.
• Levocetirizine can increase the sedative effects of CNS depressants such as benzodiazepines and opioids.
• Antihistamines like diphenhydramine may have additive effects when combined with levocetirizine, causing excessive drowsiness.
• Inhibitors of the CYP3A4 enzyme, including some protease inhibitors and azole antifungals, may increase levocetirizine levels.
• Grapefruit juice should be avoided as it may inhibit the metabolism of levocetirizine, leading to higher plasma concentrations.

Following are the food interactions for Levocetirizine Syrup/Suspension:

• Consuming alcohol with Levocetirizine can increase the risk of drowsiness and dizziness, so it is advisable to avoid or limit alcohol intake.
• Grapefruit and grapefruit juice should be avoided as they can affect the metabolism of Levocetirizine, potentially leading to increased drug levels in the body and heightened side effects.
• Dairy products like milk or yogurt may interfere with the absorption of Levocetirizine, so it is recommended to take the medication on an empty stomach, at least 1 hour before or 2 hours after meals.
• Caffeine-rich foods and beverages such as coffee, tea, and energy drinks may counteract the sedating effects of Levocetirizine, making it less effective for allergy symptoms.
• Foods high in sugar content can potentially increase the absorption of Levocetirizine, so it is advisable to monitor sugar intake and follow the prescribed dosage.
• Fatty meals can delay the absorption of Levocetirizine, leading to a potential reduction in its effectiveness, so it is best to take the medication on an empty stomach.
• Levocetirizine may be taken with a light meal if the medication causes stomach upset, but it's important to maintain a consistent routine to ensure optimal absorption.
• Always follow the instructions provided by your healthcare professional regarding food and medication interactions to ensure the best therapeutic outcome.

Levocetirizine Syrup/Suspension should be stored with care, in a dry and cool place, preferably at room temperature, ensuring it remains protected from direct sunlight and moisture. Keep the medication securely sealed in its original container to maintain its integrity and prevent contamination. It is crucial to avoid storing it in the bathroom or near heat-emitting appliances to prevent temperature-related degradation. Regularly check the expiration date, and if the medication is no longer needed or has expired, do not dispose of it via household drains or toilets. Instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep the medication securely stored away from children to prevent accidental consumption.

Following are the quick tips for Levocetirizine Syrup/Suspension:

• Administer the prescribed dosage as directed by your healthcare professional.
• Ensure you shake the bottle vigorously before each use to maintain consistency.
• Take the syrup with water; avoid tea, coffee, or dairy to enhance absorption.
• Maintain a consistent daily routine for dosing to maximize effectiveness.
• Consider taking it with food if stomach discomfort occurs.
• Store the syrup safely away from children's reach.
• Always consult your doctor or pharmacist if you have any concerns or questions.