Nezkil (400mg) 10 Tablets

Nezkil (400mg) 10 Tablets

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  • Manufacturer Continental Pharmaceuticals Limited
  • Generic Name Linezolid

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Description

    Linezolid is a powerful antibiotic used to treat numerous types of bacterial infections. It operates by targeting the formation of bacteria's cell walls, causing the bacteria to die. This medication is employed to address various infections, including skin infections such as MRSA and VRE, pneumonia caused by susceptible bacteria such as MRSA, complications related to abdominal surgery, and multidrug-resistant tuberculosis when other medications fail to work. Linezolid is available in the form of intravenous infusions and oral tablets/capsules in different concentrations of 100, 200, and 400 mg. The dosage and duration of the treatment vary according to the type and severity of the infection, as well as factors such as weight and age. It is crucial to take linezolid consistently with food to ensure maximum absorption. It is essential to complete the full course of the medication, even if symptoms improve, to prevent the development of antibiotic resistance. While linezolid has proven effective and has led to a decrease in mortality rates among patients with serious infections, it can also cause some side effects, such as nausea, diarrhea, headache, vomiting, and fever. In rare cases, linezolid can cause a severe and potentially life-threatening condition known as "linezolid-associated myelosuppression."

  • Ingredients

    Linezolid
  • Drug Class

    Monoamine Oxidase (Mao) Inhibitors

  • Dosage Form

    Tablet
  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Linezolid is an antibiotic used to treat bacterial infections
    • It is active against Gram-positive bacteria, including staphylococcus, streptococcus, and enterococcus strains. It also works against anthrax and some strains of tuberculosis.
    • Linezolid is also used for certain fungal infections, but its primary use is against bacterial infections.
    • Linezolid is typically used for the treatment of serious bacterial infections due to its potent antimicrobial properties.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Fever- Take 1 tablet of Linezolid 400mg every 12 hours, preferably before breakfast and before bedtime.
    • COPD (Chronic Obstructive Pulmonary Disorder)- The recommended dose is 2 tablets of Linezolid 400mg daily for a maximum of 28 days. The dose can be reduced to 1 tablet daily if the disease is controlled.
    • NOS (New-Onset Type III Diabetic Foot Infection)- For adults, the recommended dose is 1 tablet of Linezolid 400mg injection administered every 12 hours intravenously (IV) or intramuscular (IM) for 14 days. For children, the dose should be based on body weight and administered every 12 hours IV or IM for 14 days.
  • In case of Overdose

    Linezolid is a prescription antibiotic used to treat bacterial infections, and it is generally considered safe, but it can lead to allergic reactions in some individuals. These reactions can include symptoms such as rash, hives, itching, swelling, difficulty breathing, or dizziness.In case a patient overdoses on Linezolid, it is essential to seek immediate medical attention as it is a potentially life-threatening situation that requires prompt and appropriate management. The specific treatment for an overdose may involve supportive care, where medical staff closely monitor the vital signs, manage any symptoms that occur, and provide intravenous fluids to prevent dehydration. Additional medications may also be given based on the specific symptoms or complications resulting from the overdose.

  • Missed Dose

    Maintaining a consistent medication schedule is vital for optimal therapeutic outcomes. When taking the antibiotic Linezolid 400mg, it is important to adhere to the prescribed dosage schedule. If you miss a dose, you should take it as soon as possible, but if it is almost time for your next scheduled dose, it is recommended to skip the missed dose and continue with the regular schedule. Overlapping doses or doubling up can lead to adverse effects and should be avoided. If you miss a dose, it is a good idea to consult with your doctor or pharmacist about the best course of action that aligns with your specific health condition and medication regimen. Consistent and timely consumption of medication is essential to ensure the effectiveness of treatment.

  • How To Use

    Before you take Linezolid, it is important to inform your doctor about any medical conditions you may have or if you are pregnant or breastfeeding. Linezolid is an antibiotic that is usually taken orally, twice a day with or without food. It is important to take Linezolid at the same time each day and to finish the full course of the medication even if your symptoms improve to prevent reinfection or drug resistance. Common side effects of Linezolid include nausea, headaches, stomach upsets, and diarrhea, which are usually mild and temporary. However, if you experience any severe side effects such as seizures, blurred vision, or an allergic reaction, you should seek medical attention immediately. If you miss a dose, take it as soon as you remember it, unless it is close to the time for your next dose. In this case, you should skip the missed dose and continue with your regular schedule. Do not double the dose to catch up. Linezolid may cause dizziness and drowsiness, and it is advised to avoid alcohol while taking the medication as it may worsen these side effects. It is important to keep Linezolid in a cool, dry place, away from direct sunlight and out of the reach of children. If you have any further questions or concerns about your specific situation, it is best to consult with your doctor or pharmacist before starting Linezolid.

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • You are allergic to Linezolid or any of the other ingredients in the medication.
    • You have a history of bleeding problems or low levels of platelets (type of blood cell that aids in blood clotting).
    • You have kidney problems or an electrolyte imbalance.
    • You require surgery or dental work in the near future.
    • You should inform your doctor about all your medical conditions, allergies, and all the medications you are currently taking to ensure Linezolid is safe for you.
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Diarrhea
    • Nausea
    • Vomiting
    • Itchiness
    • Rash
    • Slow/shallow breathing
    • Severe muscle stiffness
    • Fever
    • Low blood pressure
    • Confusion
    • Seizure
    • Irregular heartbeat
    • Liver damage
    • Loss of consciousness
    • Coma
    • Death (in severe cases)
  • Precautions & Warnings

    The warnings and precautions associated with Linezolid 400mg are:

    • Patient with a history of seizures; diabetes mellitus, liver cirrhosis.
    • Not indicated for the treatment of Gram-negative infections and catheter-related systemic infections.
    • If a concomitant Gram-negative pathogen is documented or suspected, specific Gram-negative treatment must be initiated immediately.
    • Severe renal impairment (CrCl <30 mL/min), including those undergoing haemodialysis; severe hepatic impairment.
    • Children.
    • Pregnancy and lactation.
  • Drug Interactions

    The drug interactions with linezolid include:

    • Serotonergic Agents (e.g., SSRIs) – Can increase risk of serotonin syndrome.
    • Anticoagulants (e.g., warfarin) – Can increase bleeding risk.
  • Food Interactions

    The food interactions that should be considered while using Ecasil are:

    • No significant interactions with food.
    • Taking with food may enhance absorption.
  • Storage/Disposal

    Linezolid is an antibiotic used to treat bacterial infections, and it's important to handle and store it correctly to maintain its effectiveness. When storing Linezolid, it should be kept at room temperature between 68°F to 77°F (20°C to 25°C). Exposure to excessive heat or moisture can damage the tablets, so it's crucial to avoid these conditions. It should always be kept in its original container or packaging to ensure protection from light. Linezolid should not be stored in humid areas like the bathroom, and it is important to keep it out of reach of children and pets. If you have young children in the home, be sure to securely lock the medication to prevent accidental consumption. If you have any questions or concerns about storage, always consult your doctor or pharmacist, as they may provide specific advice based on your personal circumstances.

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