Nimoden (30mg) 30 Tablets

Nimodipine, a 30mg tablet, acts as a selective calcium channel blocker, specifically targeting voltage-gated L-type calcium channels. By binding to these channels, nimodipine inhibits the influx of calcium ions into smooth muscle cells, particularly in the cerebral vasculature. This mechanism leads to vasodilation, reducing vascular resistance and promoting increased blood flow to the brain. The relaxation of smooth muscle cells in the cerebral arteries is a key aspect of nimodipine's action, helping to maintain cerebral perfusion and protect against vasospasm, which is a critical factor in its therapeutic use for conditions such as subarachnoid hemorrhage. This targeted action on calcium channels makes nimodipine effective in modulating cerebral blood flow without significantly affecting systemic blood pressure.

Calcium channel blocker.

Tablet

The following are the uses of Nimodipine 30mg Tablet:

• Used for treating bleeding in the brain due to ruptured aneurysms, reducing the risk of further complications.
• Used for managing subarachnoid hemorrhage and its associated symptoms, aiding in patient recovery.
• Used for controlling and preventing vasospasm, a common complication after brain bleeding.
• Used for improving blood flow to the brain, ensuring adequate oxygen and nutrient supply.
• Used for reducing the severity and frequency of headaches associated with brain hemorrhage.
• Used for supporting overall neurological function and promoting a faster return to normal activities.
• Used for short-term treatment during critical periods to stabilize the patient's condition.
• Used for preventing long-term neurological damage and enhancing patient outcomes.

In the case of an overdose of Nimodipine 30mg Tablets, individuals may experience severe symptoms such as low blood pressure, rapid heartbeat, dizziness, and fainting. If you suspect an overdose, seek medical assistance promptly. The immediate treatment goals are to stabilize vital signs and provide supportive care. This may include monitoring heart rate, blood pressure, and administering intravenous fluids. It is crucial to act quickly and inform healthcare professionals about the suspected overdose to ensure prompt and appropriate medical intervention.

In the case of a missed dose of Nimodipine 30mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is generally recommended not to double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare professional for advice, as they may provide specific instructions based on your medical condition and treatment plan.

To take Nimodipine 30mg Tablets, swallow the tablet whole with water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, typically starting with an initial dose of one tablet every 4 hours and adjusting as directed.

Here are the conditions and situations when Nimodipine 30mg Tablet should not be used:

• Must not be used in individuals with known allergies or hypersensitivity to Nimodipine or other calcium channel blockers.
• Contraindicated in patients with severe hypotension (very low blood pressure).
• Not suitable for individuals with aortic valve stenosis (narrowing of the aortic valve in the heart).
• Should not be used in patients with acute myocardial infarction (heart attack).
• Avoid using in individuals with acute pulmonary edema (fluid accumulation in the lungs).
• Contraindicated during breastfeeding as it may pass into breast milk and harm the nursing infant.
• Not recommended for patients with severe liver disease or impaired liver function.
• Avoid using in individuals with cerebral herniation or head injury with increased intracranial pressure.
• Should not be used in patients with unstable angina (chest pain due to reduced blood flow to the heart).

The side effects of Nimodipine 30mg Tablet may include:

• Dizziness
• Headache
• Nausea and vomiting
• Fatigue or weakness
• Flushing (feeling of warmth or redness in the face)
• Swelling of the legs or ankles (peripheral edema)
• Slow or irregular heartbeat
• Hypotension (low blood pressure)

Following are the precautions and warnings for Nimodipine 30mg Tablet:

• Patients with known hypersensitivity or allergy to Nimodipine or other calcium channel blockers should not take this medication.
• Blood pressure should be monitored regularly during treatment, especially in patients with hypertension or hypotension.
• Caution is advised in patients with liver or kidney disease, as the dosage may need adjustment.
• This medication may cause dizziness or lightheadedness; patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• Nimodipine may interact with other medications; patients should inform their doctor about all current medications to avoid potential interactions.
• Pregnant or breastfeeding women should consult their doctor before taking Nimodipine, as it may have potential risks to the fetus or infant.
• Patients should not abruptly stop taking Nimodipine without medical supervision, as sudden withdrawal may lead to health complications.

Following are the drug interactions for Nimodipine 30mg Tablet:

• Nimodipine can interact with CYP3A4 enzyme inhibitors like ketoconazole, increasing its concentration and effects.
• The effectiveness of Nimodipine may be reduced by CYP3A4 inducers such as rifampin.
• Concomitant use with beta-blockers may lead to additive effects on blood pressure and heart rate.
• Anticonvulsant medications like phenytoin can decrease Nimodipine levels, potentially reducing its efficacy.
• Nimodipine may increase the levels of cyclosporine, a medication used in organ transplantation.
• Combining with other calcium channel blockers or antihypertensive drugs can enhance blood pressure-lowering effects.
• The risk of bleeding may be increased when taken with anticoagulants or antiplatelet drugs.
• Use with caution alongside diuretics, as it may lead to excessive blood pressure reduction.

Following are the food interactions for Nimodipine 30mg Tablet:

• Grapefruit juice should be consumed with caution as it may increase the blood levels of Nimodipine, potentially leading to an increased risk of side effects.
• Alcohol intake should be avoided as it can lower blood pressure and may cause excessive dizziness or drowsiness when combined with Nimodipine.
• High-fat meals may decrease the absorption of Nimodipine, potentially reducing its effectiveness.
• Caffeine-rich foods and beverages should be limited as they may interact with Nimodipine and increase side effects like nervousness and rapid heartbeat.
• Consuming tobacco products while taking Nimodipine may decrease the drug's effectiveness and increase the risk of cardiovascular side effects.
• Avoid natural licorice as it may decrease the potassium levels in the body, which can interact with Nimodipine's effects on blood pressure.
• Herbal supplements like St. John's Wort should be used cautiously as they may alter the blood levels of Nimodipine.
• Always inform your healthcare provider about your dietary habits to ensure safe and effective use of Nimodipine.

Nimodipine 30mg Tablets should be stored in a secure and dry location, away from direct sunlight and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to air. It is crucial not to store them in bathrooms or near heat-emitting appliances to avoid temperature fluctuations that could impact their effectiveness. Dispose of any unused or expired tablets responsibly; do not flush them or pour them down the drain. Consult your pharmacist or local waste management guidelines for safe disposal practices. Ensure that the medication is kept out of children's reach to prevent accidental consumption. Regularly check the expiration date, and replace the medication if it has expired to guarantee its efficacy and safety.

Following are the quick tips for Nimodipine 30mg Tablet:

• Consult your doctor for the correct dosage and duration of treatment.
• Swallow the tablet whole with a glass of water, do not crush or chew.
• Take it as instructed, typically every 4 hours, including during the night.
• Avoid grapefruit and grapefruit juice while on this medication.
• Inform your doctor about all medications/supplements you are taking.
• Do not drive or operate machinery if you experience dizziness or sleepiness.
• Store in a cool, dry place, away from direct sunlight and moisture.