Optachlor (0.5%) 10ml Eye Drops

Chloramphenicol works by inhibiting bacterial protein synthesis. It does this by binding to the 50S ribosomal subunit of bacteria, preventing the formation of peptide bonds between amino acids. This halts the growth of bacterial proteins, thereby inhibiting the replication of bacteria. It is a broad-spectrum antibiotic, effective against a wide range of gram-positive and gram-negative bacteria, including those responsible for eye infections.

Chloramphenicol

Amphenicols

Drop

The following are the uses of Chloramphenicol Eye Drops:

• Treatment of bacterial conjunctivitis (pink eye) caused by susceptible bacteria.
• Management of ocular infections, including corneal ulcers and blepharitis.
• Treatment of other eye infections as determined by a healthcare provider.
• Prevention of bacterial infections after eye surgery or trauma.
• Used for treating other eye-related bacterial conditions as prescribed by a healthcare provider.

Following are the doses of Chloramphenicol eye drops:

• The usual dose for bacterial conjunctivitis in adults and children is one to two drops in the affected eye(s) every 2 to 4 hours, depending on the severity of the infection.
• For more severe cases or as prescribed by a healthcare provider, the frequency may be adjusted to suit the condition.
• Typically, the frequency of application can be reduced after a few days of treatment when the symptoms start improving.
• For children, the dosing will be determined based on their age and the severity of the infection, and should follow the healthcare provider's instructions closely.

In case of an overdose of Chloramphenicol eye drops, immediate medical attention should be sought. Although Chloramphenicol is primarily applied topically to the eyes, an overdose may cause increased irritation, redness, or discomfort in the eyes. If too much medication is accidentally ingested or over-applied, it is recommended to rinse the eyes with water or saline solution to remove any excess medication. It is important not to induce vomiting or take any other actions without consulting a healthcare provider. If severe symptoms such as dizziness, confusion, or visual disturbances occur, seek medical attention immediately.

If you miss a dose of Chloramphenicol eye drops, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply two doses at the same time to make up for the missed dose, as this could increase the risk of side effects. Always follow the dosing instructions provided by your healthcare provider and consult them if you're unsure about how to proceed after missing a dose.

To use Chloramphenicol eye drops typically, it should be applied to the affected eye(s) as directed. Wash your hands before applying the drops to avoid contamination. Tilt your head back, pull down your lower eyelid, and apply the prescribed number of drops into the eye. Avoid letting the dropper touch your eye to prevent contamination. It’s important to take the medication at the same time each day as prescribed to maintain consistent levels in your body and complete the full prescribed course, even if you start feeling better, to avoid the infection from returning.

Following are the situations when Chloramphenicol eye drops should not be used:

• Should not be used in individuals with a known allergy to Chloramphenicol or any of the components of the drop.
• Contraindicated in patients with a history of hypersensitivity or severe allergic reactions to Chloramphenicol.
• Not recommended for use in patients with a known history of bone marrow disorders.
• Should not be used if the eye infection is caused by a viral or fungal infection, as it is not effective against those.

The side effects of Chloramphenicol eye drops may include:

• Eye irritation
• Redness
• Burning or stinging sensation
• Blurry vision
• Sensitivity to light
• Allergic reactions such as itching or swelling around the eyes
• Uncommon side effects like skin rashes or systemic reactions (e.g., fever, sore throat) if absorbed in large amounts

Following are the precautions and warnings for Chloramphenicol eye drops:

• Should not be used in individuals with a known allergy to Chloramphenicol or any of its components.
• Caution is advised in patients with a history of blood disorders, including bone marrow suppression or anemia, as the medication can cause further suppression.
• Not recommended for prolonged use due to the risk of developing resistance or adverse effects like bone marrow suppression.
• Use with caution in patients with pre-existing eye conditions, as Chloramphenicol may worsen certain eye diseases or cause additional irritation.
• Do not wear contact lenses while using Chloramphenicol drops unless directed by a healthcare provider.

Following are the drug interactions for Chloramphenicol eye drops:

• Concomitant use with other ocular medications, particularly corticosteroids, may increase the risk of glaucoma or other eye-related side effects.
• Caution should be exercised if used with other antibiotics, as the effectiveness of one may be diminished.
• Patients using multiple eye drops should space out their administration by at least 5 minutes to avoid interference with absorption.
• Be cautious when using Chloramphenicol eye drops in combination with other drugs known to affect the bone marrow, as it may increase the risk of adverse effects.

Following are the food interactions for Chloramphenicol eye drops:

• There are no known significant food interactions with Chloramphenicol eye drops.
• It is recommended to avoid consuming large amounts of alcohol, as it can potentially affect the immune system, although this is not directly related to the eye drops.
• Always follow your healthcare provider’s advice on any dietary restrictions while using the medication.

Chloramphenicol eye drops should be stored at room temperature, away from excess heat and moisture. Keep the bottle tightly closed when not in use, and store it upright. Ensure that the eye drops are kept out of reach of children. Once opened, the drops should generally be discarded after 28 days, or as directed by your healthcare provider, to prevent bacterial contamination and ensure the effectiveness of the medication. Do not use the drops if they have changed in color, consistency, or if there are any visible particles. For disposal, do not flush the medication down the toilet or drain; consult your pharmacist or healthcare provider for proper disposal methods.

Following are the quick tips for Chloramphenicol Eye Drops:

• Use Chloramphenicol eye drops as prescribed by your healthcare provider for optimal results.
• Wash your hands before applying the drops to avoid contamination.
• Tilt your head back, pull down your lower eyelid, and apply the prescribed number of drops into the eye without letting the dropper touch your eye.
• Avoid wearing contact lenses while using the drops unless directed otherwise by your healthcare provider.
• Do not share your eye drops with others, as it can lead to cross-contamination or spread of infection.