Orelox (100mg) 10 Tablets

Cefpodoxime, the active ingredient in Cefpodoxime 100mg Tablets, is a third-generation cephalosporin antibiotic. Its primary mechanism of action is inhibiting bacterial cell wall synthesis. Cefpodoxime binds to and blocks the activity of penicillin-binding proteins (PBPs) located on the bacterial cell wall, which are essential for cross-linking peptidoglycan strands during cell wall formation. By disrupting the synthesis of the peptidoglycan layer, Cefpodoxime weakens the bacterial cell wall, leading to cell lysis and bacterial death. This antibiotic is particularly effective against a wide range of Gram-positive and Gram-negative bacteria, as it can penetrate the bacterial cell wall and exert its bactericidal effect.

Cefpodoxime 100mg

Cephalosporin antibiotic

Tablet

The following are the uses of Cefpodoxime 100mg Tablet:

• Used for treating bacterial infections such as pneumonia, bronchitis, and sinusitis.
• Used for managing skin and soft tissue infections like cellulitis and impetigo.
• Effective for treating urinary tract infections, particularly those caused by E. coli.
• Used for addressing acute otitis media (middle ear infection) in children.
• Can be prescribed for preventing infections after surgery or injury.
• Used for controlling respiratory tract infections, including strep throat.
• Provides relief from bacterial conjunctivitis (pink eye) when applied topically.

Follow these dosage instructions:

• Adults and Adolescents Dosage (12 years and older)

Take the tablet or oral suspension as per the doctor's recommendation. The daily recommended dosage is 200mg to 400mg. Only in case of skin infections, the dosage can be taken up to 800mg.

• Infants and Pediatric Dosage (Ages 2 months through 12 years)

For the pediatric population, the daily recommended dosage is 10mg.

In the case of an overdose of Cefpodoxime 100mg Tablets, it is important to seek medical advice promptly. Symptoms of an overdose may include nausea, vomiting, and diarrhea. If you suspect an overdose, contact a healthcare professional or go to the nearest emergency room. Treatment may involve supportive care to manage symptoms and ensure the individual's stability. It is crucial to act quickly and not delay seeking medical assistance.

In the case of a missed dose of Cefpodoxime 100mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you have missed multiple doses, contact your healthcare provider for guidance on how to get back on track with your medication schedule safely. It is recommended to set reminders or alarms to help you remember to take your medication at the correct times.

To take Cefpodoxime 100mg Tablet, swallow the tablet whole with a full glass of water, ensuring you complete the entire course as prescribed by your healthcare provider, typically taken once or twice a day as directed.

Following are the conditions when Cefpodoxime 100mg Tablet should not be used:

• Avoid if allergic to Cefpodoxime or any other cephalosporin antibiotics.
• Do not use if you have a history of severe allergic reactions to penicillin.
• Contraindicated in patients with a history of cholestatic jaundice/liver problems caused by Cefpodoxime.
• Should not be used if you have severe kidney disease, as dosage adjustments may not be sufficient.
• Not recommended for individuals with a history of severe gastrointestinal diseases.
• Avoid in patients with a history of severe or life-threatening skin reactions to antibiotics.
• Do not use if you have a history of seizures, as it may increase the risk of convulsions.

The side effects of Cefpodoxime 100mg Tablet may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain
• Skin rash or itching
• Headache
• Dizziness
• Vaginal yeast infection
• Fatigue

Following are the precautions and warnings for Cefpodoxime 100mg Tablet:

• This medication should not be used if you are allergic to Cefpodoxime or any similar antibiotics like cephalosporins.
• Patients with a history of kidney disease should exercise caution, as dosage adjustments might be necessary for those with renal impairment.
• Cefpodoxime may reduce the effectiveness of certain birth control pills, so alternative contraceptive methods are recommended during treatment.
• It may cause diarrhea, and in rare cases, it can indicate a new infection; immediate medical attention is required if it is severe or persistent.
• Avoid using the tablet if you have ever had a severe allergic reaction to similar antibiotics, as it can lead to life-threatening conditions.
• Inform your doctor if you have a history of gastrointestinal diseases or kidney-related disorders before taking this medication.
• Cefpodoxime should be used with caution in elderly patients, as they may be more susceptible to side effects.

Following are the drug interactions for Cefpodoxime 100mg Tablet:

• Probenecid, a medication used to treat gout, can decrease the excretion of cefpodoxime, leading to increased blood levels of the antibiotic.
• Cefpodoxime may reduce the effectiveness of oral contraceptives, so alternative or additional contraceptive methods are recommended during treatment.
• Antacids containing magnesium or aluminum can decrease the absorption of cefpodoxide, so separate administration by at least 2 hours.
• Nephrotoxic drugs (e.g., aminoglycosides, diuretics) may increase the risk of kidney damage when used with cefpodoxime, especially in patients with pre-existing renal impairment.
• Cefpodoxime can potentially reduce the efficacy of live bacterial vaccines (such as typhoid vaccine), so vaccination should be completed before starting the antibiotic.
• The effectiveness of cefpodoxime may be reduced when used with medications that decrease gastric acidity, such as proton pump inhibitors or H2-receptor antagonists.
• Caution is advised when using cefpodoxime with other antibiotics that have a similar mechanism of action, as it may increase the risk of bacterial resistance.

Following are the food interactions to be aware of when taking Cefpodoxime 100mg Tablets:

• Avoid consuming alcohol during the medication course as it may reduce the effectiveness of Cefpodoxime and increase the risk of side effects like stomach upset and dizziness.
• Grapefruit and grapefruit juice should be consumed with caution as they can affect the metabolism of Cefpodoxime, potentially leading to increased drug levels in the body and a higher risk of adverse reactions.
• High-fat meals may delay the absorption of Cefpodoxime, which could result in reduced antibiotic effectiveness. Consider taking the medication on an empty stomach or as directed by your healthcare provider.
• Dairy products like milk, yogurt, and cheese may interfere with the absorption of Cefpodoxime, especially when consumed in large quantities. Separate them by a few hours to ensure optimal drug absorption.
• Caffeinated beverages like coffee and tea might enhance the elimination of Cefpodoxime from the body, potentially reducing its effectiveness. Consider limiting caffeine intake during treatment.
• Avoid consuming iron-rich foods or supplements simultaneously with Cefpodoxime, as iron can interfere with antibiotic absorption. Separate them by a few hours for better medication absorption.
• Vitamin C supplements or citrus fruits high in vitamin C may alter the pH of the stomach, potentially affecting Cefpodoxime absorption. Consider taking vitamin C supplements at a different time of day.
• Probiotics, while generally beneficial, might interact with Cefpodoxime, potentially reducing its efficacy. Consult your healthcare provider for guidance on probiotic use during antibiotic treatment.

Cefpodoxime 100mg Tablets should be stored in a cool, dry location, preferably at room temperature, and protected from light and moisture. It is crucial to keep the tablets in their original container, securely sealed, to maintain their integrity and prevent contamination. Avoid storing them in hot environments like the kitchen or near appliances that generate heat, as high temperatures can degrade the medication. Always adhere to the expiration date printed on the packaging, and for the safe disposal of any unused or expired tablets, consult your pharmacist or healthcare professional. It is vital to keep all medications out of the reach of children to prevent accidental consumption. Never discard pharmaceutical waste in sinks or toilets, as it can cause environmental harm.

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Following are the quick tips for Cefpodoxime 100mg Tablet:

• Always take the medicine as directed by your doctor; do not self-medicate.
• Complete the full course of medication to ensure the infection is completely treated.
• Swallow the tablet with a full glass of water; do not crush, chew, or break it.
• Cefpodoxime can be taken with or without food, but taking it with food may reduce stomach upset.
• Avoid consuming alcohol as it may increase the risk of side effects.
• If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose.
• Store the tablets at room temperature, away from moisture and direct sunlight.