Panadol CF Day 100 Caplets

Phenylephrine, an active ingredient in the tablet, acts as an alpha-adrenergic receptor agonist, primarily targeting the alpha-1 receptors in the blood vessels of the nasal passages and sinuses. By stimulating these receptors, phenylephrine causes vasoconstriction, leading to the narrowing of blood vessels and reduced blood flow to the nasal mucosa. This results in decreased congestion and inflammation in the nasal passages, providing relief from symptoms such as nasal congestion and sinus pressure. Paracetamol, on the other hand, is an analgesic and antipyretic agent. It works by inhibiting the synthesis of prostaglandins, which are involved in pain and fever signaling pathways. Paracetamol blocks cyclooxygenase (COX) enzymes, reducing the production of prostaglandins, thereby alleviating pain and lowering elevated body temperature.

Antihistamine, Analgesic.

Tablet

The following are the uses of Phenylephrine, Paracetamol Tablet:

• Used for temporarily relieving nasal congestion caused by the common cold, sinusitis, or allergies.
• Used for reducing fever and providing pain relief for mild to moderate pain such as headaches, toothaches, and menstrual cramps.
• Used for treating symptoms of upper respiratory tract infections, including sinus pressure and headache.
• Used for helping ease discomfort and reduce inflammation associated with sinus congestion.
• Used for managing symptoms of cold and flu, including nasal stuffiness and headache.
• Used for providing temporary relief from minor aches and pains, allowing for improved comfort.
• Used for promoting sinus drainage and reducing facial pain related to sinus issues.

1-2 tablets can be taken every 4-6 hours. Do not take for prolonged periods of time.

In the case of an overdose of Phenylephrine and Paracetamol Tablets, individuals may experience severe symptoms such as rapid heartbeat, high blood pressure, and increased body temperature. This can lead to potential complications, including organ damage and failure. Prompt medical intervention is necessary to manage these effects, which may include administering activated charcoal to prevent further absorption and providing supportive care to stabilize vital signs. It is crucial to seek emergency assistance if an overdose is suspected.

In the case of a missed dose of Phenylephrine and Paracetamol Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for a missed one, as this may increase the risk of side effects. For Phenylephrine, if you miss a dose, take it as soon as possible, but skip it if it's almost time for the next dose. With Paracetamol, if you miss a dose, take it as soon as you remember, but if it's close to the next dose time, skip the missed dose and continue with your regular schedule.

To take the Phenylephrine, Paracetamol Tablet, swallow the tablet whole with a glass of water, following the prescribed dosage instructions provided by your healthcare professional, typically taken every 4 to 6 hours as needed for pain relief and congestion, but not exceeding the maximum daily dosage recommended by your doctor.

Following are the conditions or circumstances when Phenylephrine and Paracetamol Tablet should be avoided:

• Avoid if you have known allergies to Phenylephrine, Paracetamol, or any other decongestant or analgesic medications.
• Not suitable for individuals with narrow-angle glaucoma or those who have difficulty urinating due to an enlarged prostate.
• Contraindicated in patients with severe hypertension (high blood pressure) or cardiovascular disease.
• Should not be used if you have taken a monoamine oxidase inhibitor (MAOI) in the last 14 days.
• Avoid using this medication if you have severe coronary artery disease, aortic aneurysms, or if you have recently had any type of surgery.
• Not recommended for individuals with pheochromocytoma, a tumor of the adrenal gland.
• Do not use if you have severe liver or kidney disease.
• Avoid using this medication if you have a history of stomach ulcers or bleeding disorders.

The side effects of Phenylephrine, Paracetamol Tablet may include:

• Increased heart rate
• High blood pressure
• Nervousness or anxiety
• Dizziness or lightheadedness
• Nausea or vomiting
• Dry mouth
• Difficulty in urination
• Skin rashes or itching

Following are the precautions and warnings for Phenylephrine, Paracetamol Tablet:

• Avoid use if you are allergic to phenylephrine or paracetamol, or any other decongestant or pain reliever medications.
• This medication should be used with caution in patients with hypertension, heart disease, diabetes, thyroid problems, or prostate issues as it may worsen these conditions.
• Do not exceed the recommended dosage, as excessive use can lead to liver damage or other serious side effects.
• Patients with kidney or liver disease should exercise caution and consult a doctor before use, as dosage adjustments may be necessary.
• Avoid alcohol consumption while taking this medication as it may increase the risk of liver damage.
• If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medication.
• Do not use this medication for prolonged periods without consulting a healthcare professional.

Following are the drug interactions for Phenylephrine, Paracetamol Tablet:

• Monoamine oxidase inhibitors (MAOIs) should not be used concurrently, as it may cause severe hypertension.
• May decrease the antihypertensive effect of beta-blockers and other antihypertensive drugs.
• Concomitant use with other sympathomimetic agents can lead to increased cardiovascular side effects.
• Can reduce the efficacy of urinary alkalinizing agents used to increase urinary pH.
• Paracetamol may interact with warfarin, increasing the risk of bleeding.
• The hepatotoxic potential may be increased when combined with other potentially hepatotoxic drugs.
• Concomitant use with alcohol may increase the risk of liver damage.

Following are the food interactions for Phenylephrine, Paracetamol Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they may interfere with the breakdown of the medication, potentially leading to increased side effects.
• Alcohol intake should be limited as it can intensify the sedative effects of the Paracetamol, increasing the risk of liver damage, especially with prolonged use.
• Caffeine-containing beverages should be consumed in moderation as they can enhance the stimulant effects of Phenylephrine, potentially causing increased heart rate and blood pressure.
• Avoid excessive consumption of fatty foods as they may slow down the absorption of Paracetamol, affecting its effectiveness.
• Maintain a balanced diet, ensuring adequate fluid intake to prevent dehydration, which can impact the effectiveness of the medication.
• Spicy foods may potentially increase the risk of stomach irritation when taking Paracetamol, so consider moderation.
• Always follow the advice of your healthcare professional regarding specific dietary recommendations while using this medication.

Phenylephrine and Paracetamol Tablets should be stored in a cool, dry place, preferably at room temperature, ensuring protection from light and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to air. It's crucial not to store them in the bathroom or near heat-emitting appliances, as temperature fluctuations can impact their effectiveness. Dispose of any unused or expired tablets responsibly; do not flush them or pour them down the drain. Contact your pharmacist or healthcare provider for guidance on safe disposal methods. Always keep medications out of children's reach to prevent accidental ingestion.

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Following are the quick tips for Phenylephrine, Paracetamol Tablet:

• Consult your doctor or pharmacist for the recommended dosage based on your age and medical condition.
• Take the tablet with a full glass of water for better absorption.
• Avoid consuming alcohol while taking this medication as it may intensify side effects.
• Do not crush or chew the tablet; swallow it whole for optimal effectiveness.
• Inform your doctor about all medications you are taking to prevent potential drug interactions.
• If you experience dizziness, lie down until it passes to prevent injuries.
• Store the medication in a cool, dry place, away from direct sunlight and moisture.
• Do not share your medication with others, even if they have similar symptoms.