Promto (20mg) 10 Tablets

Rabeprazole 10mg Tablet primarily works by inhibiting the proton pump in the stomach, which is responsible for acid production. It specifically targets the H+/K+-ATPase enzyme system, also known as the gastric proton pump, found in the parietal cells of the stomach. By binding to this pump, rabeprazole blocks the secretion of gastric acid, leading to a rapid and significant reduction in the production of stomach acid. This mechanism effectively suppresses the highly acidic environment required for the activation of pepsin, a digestive enzyme, thereby reducing the overall acidity in the stomach and helping to alleviate symptoms associated with acid-related conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers.

Proton pump inhibitor.

Tablet

The following are the uses of Rabeprazole 10mg Tablet:

• Used for treating gastroesophageal reflux disease (GERD) by reducing stomach acid production.
• Used to relieve symptoms like heartburn, difficulty swallowing, and persistent cough.
• Used for managing conditions like Zollinger-Ellison syndrome, where excessive acid is produced.
• Used to heal acid-related damage in the stomach and esophagus.
• Used to prevent stomach ulcers and promote their healing.
• Used as a maintenance therapy to prevent the return of ulcers.
• Used in combination with antibiotics to treat stomach infections caused by bacteria.
• Used to create a more favorable environment for the healing of gastrointestinal issues.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Gastroesophageal reflux disease (GERD) or heartburn - 20 mg once daily in the morning for up to 4 weeks, switch to prescription strength PPIs (like omeprazole) for continued use beyond 4 weeks.
• Ulcerative colitis - 20 mg once daily for 6 weeks.
• Duodenal ulcer - 20 mg once daily for 4 weeks.
• Stomach ulcer - 20 mg once daily for 4 weeks.
• Gastric cancer - 20 mg every morning preferably an hour before breakfast.
• Zollinger-Ellison syndrome - Initially, 20 mg once daily. The dose may be increased to 20 mg every day divided into two doses.

In the case of an overdose of Rabeprazole 10mg Tablets, individuals may experience a range of symptoms. These can include nausea, vomiting, headache, and dizziness. The severity of the effects may vary depending on the amount ingested. It is important to note that while overdoses can be concerning, they are rarely life-threatening. However, if you suspect an overdose, it is advisable to seek medical advice promptly to ensure appropriate monitoring and management of any potential side effects.

In the case of a missed dose of Rabeprazole 10mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare professional for guidance on how to safely resume your medication and maintain its effectiveness. It's best to set a reminder to help you stay on track with your prescribed dosing schedule.

To take Rabeprazole 10mg Tablet, swallow the tablet whole with a glass of water, preferably in the morning before a meal, as directed by your healthcare provider, and follow the prescribed dosage instructions for optimal effectiveness.

Following are the conditions when Rabeprazole 10mg Tablet should not be used:

• Avoid using if you have a known allergy to Rabeprazole or other proton pump inhibitors (PPIs).
• Do not take this medication if you have severe liver problems.
• Not recommended for individuals with low magnesium levels in the blood (hypomagnesemia).
• Contraindicated if you are currently taking a medication that contains rilpivirine.
• Should not be used as a short-term treatment for relief of acute symptoms of acid reflux.
• Avoid using if you have an inherited condition causing poor liver function (hepatic porphyria).

The side effects of Rabeprazole 10mg Tablet may include:

• Headache
• Diarrhea
• Abdominal pain
• Nausea
• Dizziness
• Constipation
• Skin rashes
• Increased risk of fractures with long-term use.

Following are the precautions and warnings for Rabeprazole 10mg Tablet:

• This medication is not recommended for individuals with known hypersensitivity or allergy to Rabeprazole or other proton pump inhibitors.
• Long-term use may lead to vitamin B12 deficiency, so regular monitoring is necessary.
• Patients with liver problems should exercise caution and consult a doctor, as Rabeprazole may affect liver function.
• It may increase the risk of bone fractures with long-term use, especially in high doses or for those with osteoporosis.
• Elderly patients should be closely monitored for adverse effects, as they may be more susceptible to certain side effects.
• Not recommended for use during pregnancy or breastfeeding unless the potential benefits outweigh the risks.
• May interact with other medications, especially those metabolized by the liver, so inform your doctor about all the medications you are taking.

Following are the drug interactions for Rabeprazole 10mg Tablet:

• It may reduce the absorption of drugs that require stomach acidity for absorption, such as ketoconazole, atazanavir, and iron salts.
• Concomitant use with digoxin may increase digoxin levels, requiring monitoring.
• Rabeprazole can decrease the effectiveness of clopidogrel, a blood thinner, potentially reducing its antiplatelet effect.
• The effect of anticoagulants like warfarin may be altered, requiring close monitoring of INR values.
• It can increase plasma concentrations of methotrexate, especially at high doses, which may increase methotrexate toxicity.
• Drugs that depend on gastric pH for activation, such as ampicillin esters, may have reduced bioavailability.
• May interact with certain antiretroviral medications, affecting their plasma concentrations.

Following are the food interactions for Rabeprazole 10mg Tablet:

• Avoid excessive consumption of spicy foods, as they can irritate the stomach lining and reduce the effectiveness of Rabeprazole in managing acid-related conditions.
• Grapefruit and grapefruit juice should be consumed with caution as they may interfere with the metabolism of Rabeprazole, potentially leading to increased drug levels in the body.
• Limit alcohol intake as it can irritate the stomach and potentially worsen gastrointestinal issues, reducing the medication's efficacy.
• High-fat meals may delay the absorption of Rabeprazole, so it is advisable to take the medication on an empty stomach for optimal absorption.
• Caffeinated beverages like coffee and tea may stimulate acid production and potentially counteract the effects of Rabeprazole, so moderation is recommended.
• Dairy products, especially milk, can interact with Rabeprazole by reducing its absorption. Consider separating the medication and dairy intake by a few hours.
• Avoid excessive consumption of acidic foods like citrus fruits and tomatoes, as they can aggravate stomach issues and potentially decrease the medication's effectiveness.
• Maintain a balanced diet, ensuring adequate intake of vitamins and minerals, as prolonged use of Rabeprazole may impact nutrient absorption.

Rabeprazole 10mg Tablets should be stored in a dry, cool place, ideally at room temperature between 68°F and 77°F (20°C and 25°C). Protect the tablets from excessive heat, moisture, and direct sunlight, as these conditions can degrade the medication. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to air and humidity. It is crucial to dispose of any unused or expired medication properly, but never flush them down the toilet or pour them into a drain. Consult your pharmacist or local waste disposal company for guidance on safe disposal methods. Ensure that the medication is stored out of children's reach to prevent accidental consumption.

Following are the quick tips for Rabeprazole 10mg Tablet:

• Take the tablet as directed by your doctor, usually once daily.
• Swallow the tablet whole with a glass of water, preferably in the morning.
• Avoid crushing, chewing, or breaking the tablet.
• Take the medication regularly for the prescribed duration, even if you feel better early on.
• If you miss a dose, take it as soon as you remember, unless it's almost time for the next dose.
• Do not double the dose to make up for a missed one.
• Inform your doctor about all the medicines you are currently taking to avoid potential drug interactions.

Rabeprazole is a proton pump inhibitor (PPI) that functions by reducing acid production in the stomach and is utilized to remedy stomach and duodenal ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. While Rabeprazole is generally safe, it may have potential side effects, and thus, lab tests are sometimes necessary to ensure its safe application. Among the laboratory tests that may be required are kidney function tests, which are essential as Rabeprazole can impact kidney function, especially in vulnerable populations such as older individuals or those with pre-existing kidney issues. Liver function tests may also be undertaken to check for liver inflammation or severe liver injury. Furthermore, there may be a need for blood chemistry and electrolyte tests to monitor for vitamin B12 deficiency and low magnesium levels in the blood, which can be a result of long-term PPI usage. For those taking Rabeprazole to treat an ulcer, more focused tests such as endoscopy may be recommended to assess healing and gauge the drug's efficacy. However, it is critical to emphasize that specific testing requirements should be clarified with a qualified healthcare provider, who can tailor recommendations based on one's unique conditions. Overall, while Rabeprazole is an effective treatment, lab tests may be necessary to ensure its safe and beneficial usage.