Provate-S (0.5/30mg) 15g Ointment

The mechanism of action of Betamethasone and Salicylic Acid Ointment involves the synergistic effects of its two active ingredients. Betamethasone is a potent synthetic corticosteroid that reduces inflammation by inhibiting the release of inflammatory mediators and suppressing immune responses. It binds to corticosteroid receptors in the skin, altering the expression of various genes involved in inflammation and immune function. Salicylic acid, on the other hand, is a keratolytic agent that promotes the shedding of dead skin cells and helps to soften and remove hyperkeratotic lesions. It achieves this by dissolving the intercellular cement that holds the skin cells together, facilitating the loosening and removal of scaly, hyperkeratotic skin. When combined, these two ingredients work together to reduce inflammation, relieve itching, and soften and eliminate thickened or scaly skin associated with various dermatological conditions.

Betamethasone, Salicylic Acid

Corticosteroid, keratolytic ointment

Ointment

The following are the uses of Betamethasone, Salicylic Acid Ointment:

• Used for treating psoriasis and other severe skin conditions, reducing redness, itching, and inflammation.
• Used to relieve symptoms of skin conditions like eczema, dermatitis, and rashes.
• Used to treat scalp psoriasis, softening and removing scaly plaques.
• Used for treating itching, irritation, and redness caused by insect bites or allergic reactions.
• Used for reducing inflammation and promoting healing in skin injuries or wounds.
• Used to manage itching and discomfort in various skin diseases.
• Used to prevent and treat skin reactions after specific medical procedures.

To be used as per doctor's prescription

In the case of an overdose of Betamethasone and Salicylic Acid Ointment, it is important to recognize the potential side effects. Overuse can lead to increased absorption of betamethasone, resulting in typical corticosteroid side effects such as skin atrophy, striae, and telangiectasia. Additionally, excessive use of salicylic acid may cause local irritation, burning, or itching. If an overdose occurs, it is advisable to discontinue use and consult a healthcare professional for further guidance and management.

In the case of a missed dose of Betamethasone, Salicylic Acid Ointment, it is generally recommended to apply it as soon as you remember. However, if it's almost time for your next scheduled application, skip the missed dose and continue with your regular schedule. Do not apply extra medication to make up for a missed dose, as this may increase the risk of side effects. If you frequently miss doses, it's best to inform your healthcare provider, as they may provide specific instructions for your individual treatment plan.

To apply Betamethasone, Salicylic Acid Ointment, clean and dry the affected area, then gently rub a thin layer of the ointment onto the skin, ensuring it covers the affected area completely, usually twice a day or as directed by your healthcare provider.

Here are the conditions or situations when Betamethasone, Salicylic Acid Ointment should not be used:

• Avoid using on skin that is infected or has open wounds.
• Do not use on skin with a viral infection such as chickenpox or herpes.
• Not suitable for individuals with a known allergy to Betamethasone, Salicylic Acid, or any other steroid medications.
• Avoid using on the face, underarms, or groin area unless directed by a healthcare professional.
• Should not be used on skin conditions that are sensitive to steroids or have a history of poor reaction to similar treatments.
• Contraindicated for individuals with certain skin disorders like rosacea, acne, or perioral dermatitis.
• Do not use if you have a skin condition called impetigo.
• Not recommended for long-term use without medical supervision due to potential side effects of prolonged steroid use.

The side effects of Betamethasone, Salicylic Acid Ointment may include:

• Skin irritation or redness at the application site
• Itching or burning sensation
• Dry skin or peeling
• Thinning of the skin
• Acne or skin infections
• Stretch marks
• Slow wound healing

Following are the precautions and warnings for Betamethasone, Salicylic Acid Ointment:

• Avoid contact with eyes and mucous membranes. If accidental contact occurs, rinse thoroughly with water.
• Do not use on broken or infected skin, and do not apply to the face, underarms, or groin area unless directed by a doctor.
• Do not use for extended periods without medical supervision as it may lead to skin thinning, stretch marks, or other skin damage.
• Inform your doctor if you have a history of skin disorders, diabetes, or circulation problems before using this ointment.
• This medication may increase the risk of infection; avoid crowded places and individuals with infections.
• Do not cover the treated area with airtight dressings or bandages as it may increase the absorption of the medication.
• Children and elderly patients should use this medication with caution and under medical supervision.

Following are the drug interactions for Betamethasone and Salicylic Acid Ointment:

• Using Betamethasone with other corticosteroids may increase the risk of systemic corticosteroid side effects, including adrenal suppression and immune system suppression.
• Caution is advised when applying the ointment on large areas or broken skin, as the absorption of Betamethasone can increase, potentially leading to systemic effects.
• Salicylic acid may enhance the absorption of other topical medications, so it is important to avoid using it with other topical steroids or irritants.
• Salicylic acid may interact with anticoagulants (e.g., warfarin), increasing the risk of bleeding, particularly if used over large areas of the skin.
• Concurrent use with other topical products containing alcohol or harsh chemicals can increase skin irritation or dryness.
• When used with other salicylates (e.g., aspirin), there may be an increased risk of salicylate toxicity, particularly if absorbed systemically in large amounts.
• Betamethasone may interact with drugs that affect the metabolism of steroids (e.g., ketoconazole, ritonavir), potentially altering its effectiveness and risk of side effects.
• Use caution if combining with drugs that may cause skin thinning, as both Betamethasone and Salicylic Acid can contribute to this effect when used in high doses or over long periods.

Following are the food interactions for Betamethasone, Salicylic Acid Ointment:

• Betamethasone may cause an increase in blood sugar levels, so patients with diabetes should monitor their glucose levels regularly and adjust their diet as advised by their doctor.
• Salicylic acid can sometimes cause stomach irritation, so it is advisable to avoid spicy or acidic foods that may worsen this effect.
• Foods rich in vitamin D, such as fatty fish, egg yolks, and fortified dairy products, should be consumed in moderation as Betamethasone can affect vitamin D metabolism.
• Salicylic acid may decrease the absorption of folic acid, so ensure an adequate intake of folate-rich foods like leafy greens, legumes, and citrus fruits.
• Avoid excessive salt intake, as Betamethasone can cause sodium retention, leading to increased blood pressure.
• Limit caffeine intake from coffee, tea, and energy drinks as it may interact with Betamethasone and affect its effectiveness.
• Avoid grapefruit and grapefruit juice, as they can interfere with the metabolism of Betamethasone, potentially increasing its levels in the body.

Betamethasone, Salicylic Acid Ointment should be stored in a cool and dry place, preferably at room temperature, ensuring it is protected from direct sunlight and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to store the ointment in the bathroom or near heat sources, as temperature fluctuations can impact its effectiveness. Dispose of any leftover or expired ointment responsibly; do not flush it or pour it down the drain. Consult your pharmacist or healthcare professional for appropriate disposal methods to minimize environmental impact. Keep this medication securely stored, away from children, to prevent accidental exposure.

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Following are the quick tips for Betamethasone and Salicylic Acid Ointment:

• Apply a thin layer to the affected area as directed by your doctor or pharmacist.
• Wash your hands before and after application to avoid spreading the medication.
• Use the ointment as instructed, ensuring complete coverage of the affected skin.
• Do not cover the treated area with bandages or tight clothing unless directed by your healthcare provider.
• Avoid contact with eyes and mucous membranes; rinse thoroughly with water if contact occurs.
• Inform your doctor if your condition doesn't improve or worsens after a few days of treatment.
• Store the ointment at room temperature, away from excessive heat and moisture.