Quadro (300mcg) 30 Tablets

Quatrefolic 300 mcg Tablet contains the active ingredient folic acid (also known as vitamin B9), which plays a crucial role in various physiological processes. The mechanism of action of Quatrefolic involves its conversion to the active form of folate, known as 5-methyltetrahydrofolate (5-MTHF), in the body. This conversion is facilitated by an enzyme called methylenetetrahydrofolate reductase (MTHFR). 5-MTHF is essential for DNA synthesis, repair, and methylation processes, particularly in rapidly dividing cells. By providing the body with an active form of folate, Quatrefolic supports the production and maintenance of healthy cells, aids in the formation of red blood cells, and helps prevent folate deficiency-related disorders, such as neural tube defects during pregnancy.

Folic acid derivative

Tablet

The following are the uses of Quatrefolic 300mcg Tablet:

• Used for treating Folic Acid deficiency
• Used to prevent and treat Folate-deficiency Anaemia
• Used to reduce Homocysteine levels in the body
• Used to support healthy brain and nerve function during pregnancy
• Used to reduce the risk of Neural Tube Defects in unborn babies
• Used for women planning pregnancy or in the first trimester
• Used as a supplement when dietary intake is inadequate
• Used to support overall health and development during pregnancy

To be used as per doctor's prescription

In the case of an overdose of Quatrefolic 300mcg Tablets, it is important to remain calm and seek medical advice promptly. While rare, symptoms may include nausea, abdominal discomfort, or diarrhea. Contact a healthcare professional or poison control center for guidance, as they can provide specific instructions for managing the situation. Prompt action and consultation can help ensure the best possible outcome in the event of an overdose.

In the case of a missed dose of Quatrefolic 300mcg Tablet, it is generally advised to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss several doses, consult your healthcare professional for advice on how to re-establish your treatment routine and ensure the best outcomes.

To take Quatrefolic 300mcg Tablet, place the tablet under your tongue and allow it to dissolve completely, preferably without swallowing for at least 30 seconds to ensure optimal absorption.

Following are the conditions/situations when Quatrefolic 300mcg Tablet should not be used:

• Avoid using if you have a known allergy or sensitivity to 5-methyltetrahydrofolate, or any other ingredients in the formulation.
• Not suitable for individuals with a history of anaphylactoid reactions to folic acid or folate compounds.
• Should not be used as a treatment for pernicious anemia or other megaloblastic anemias where vitamin B12 is deficient.
• Not recommended for individuals with untreated or undiagnosed vitamin B12 deficiency.
• Contraindicated in patients with a rare genetic disorder called anaphylaxis-shock.

The side effects of Quatrefolic 300mcg Tablet may include:

• Gastrointestinal issues such as nausea, vomiting, diarrhea, or abdominal pain.
• Skin reactions like rashes, itching, or hives.
• Dizziness or lightheadedness.
• Headaches or migraines.
• Fatigue and weakness.
• Sleep disturbances, including insomnia or excessive sleepiness.
• Mood changes, such as irritability or anxiety.
• Allergic reactions, which can lead to difficulty breathing, swelling of the face or throat, and severe dizziness.

Following are the precautions and warnings for Quatrefolic 300mcg Tablet:

• Not suitable for individuals with a known hypersensitivity or allergy to 5-methyltetrahydrofolate, calcium, or any other ingredients in the tablet.
• Patients with a history of allergic reactions to folic acid or related compounds should exercise caution and consult a healthcare professional before use.
• This medication should be used with caution in individuals with a history of vitamin B12 deficiency, as it can mask the symptoms of this condition and delay proper diagnosis.
• Patients with anemia should be aware that Quatrefolic may not be sufficient to treat their condition and should continue their prescribed treatment.
• Caution is advised for individuals with impaired renal function, as the dosage may need adjustment in cases of severe kidney disease.
• Not recommended for children, and elderly patients may require a lower dose, so medical advice is essential for these age groups.
• Pregnant and breastfeeding women should consult their healthcare provider before taking this medication to ensure proper dosage and safety.
• If you are taking any other medications, especially those affecting folate metabolism, consult your doctor to ensure there are no interactions.

Following are the drug interactions for Quatrefolic 300mcg Tablet:

• Antiepileptic drugs (e.g., phenytoin, carbamazepine) may reduce the effectiveness of Quatrefolic.
• Methotrexate, a chemotherapy drug, can interfere with folate metabolism, reducing the efficacy of Quatrefolic.
• Proton pump inhibitors (PPIs) like omeprazole may decrease the absorption of Quatrefolic, potentially requiring dosage adjustments.
• Sulfasalazine, used for inflammatory bowel disease, can reduce folate levels, thus decreasing the effectiveness of Quatrefolic.
• Oral contraceptives may decrease the bioavailability of folate, impacting the efficacy of Quatrefolic.
• Alcohol consumption can interfere with folate metabolism and absorption, potentially reducing the effectiveness of Quatrefolic.
• Antibiotics such as tetracyclines may decrease the absorption of folate, affecting the overall efficacy of Quatrefolic.

Following are the food interactions for Quatrefolic 300mcg Tablet:

• It is advisable to avoid excessive consumption of foods rich in folic acid like leafy green vegetables, citrus fruits, beans, and fortified cereals while taking this medication. High folic acid intake from food may impact the treatment plan.
• Grapefruit and grapefruit juice should be consumed with caution as they can affect the absorption of some medications. Consult your doctor about any potential interactions.
• Alcohol may interfere with the absorption of this medication and is generally not recommended when taking any medication. It's best to consult your healthcare provider for personalized advice.
• Dairy products like milk and yogurt may hinder the absorption of this medication. It is recommended to separate calcium-rich foods from the medication dose by at least 2 hours.
• Consuming high-fat meals while taking this medication may slow down the absorption process, potentially affecting its effectiveness. It's best to follow the timing instructions provided by your healthcare professional.
• Avoid consuming large amounts of tea or coffee, as these beverages may hinder the absorption of this medication. It's best to separate them by at least 1-2 hours.
• Vitamin C-rich foods like oranges, strawberries, and broccoli can potentially interfere with the effectiveness of this medication. It is advisable to separate the consumption of these foods from the medication by a few hours.
• Certain protein-rich foods like meat and eggs may also affect the absorption of this medication. It is recommended to maintain a consistent dietary pattern while taking this medication.

Quatrefolic 300mcg Tablets should be stored in a cool and dry place, preferably at room temperature, away from direct sunlight and moisture. It is crucial to keep the tablets in their original packaging, ensuring the container is tightly sealed to maintain their integrity. Avoid exposing the tablets to heat or placing them near sources like radiators or ovens, as temperature fluctuations can impact their effectiveness. Always check the expiration date before use, and if the tablets are expired or no longer needed, proper disposal is essential. Do not dispose of them in sinks or toilets; consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption.

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Following are the quick tips for Quatrefolic 300mcg Tablet:

• Consult your doctor for the right dosage and duration based on your medical condition.
• Take it at the same time each day to maintain consistent levels.
• Swallow the tablet whole with a glass of water, do not crush or chew.
• Ensure you complete the full course as prescribed.
• Store in a cool, dry place, away from direct sunlight and moisture.
• Inform your doctor about all medications you are taking to avoid interactions.
• Do not share this medication with others, even with similar symptoms.