Qusel (100mg) 20 Tablets

Quetiapine, the active ingredient in Quetiapine 100mg Tablets, primarily acts as an antagonist at multiple neurotransmitter receptors in the brain. Its mechanism of action involves blocking specific receptors, such as dopamine D2 and serotonin 5-HT2A receptors, which are involved in regulating mood, cognition, and perception. By binding to these receptors, quetiapine modulates neurotransmission, reducing excessive dopamine and serotonin activity. This action helps restore the balance of these neurotransmitters, leading to improved mood stabilization, reduced psychotic symptoms, and a decrease in the severity of certain mood disorders. Quetiapine's ability to target multiple receptors contributes to its effectiveness in treating conditions like schizophrenia, bipolar disorder, and major depressive disorder.

Antipsychotic

Tablet

The following are the uses of Quetiapine 100mg Tablet:

• Used for treating bipolar disorder, helping stabilize mood and prevent manic or depressive episodes.
• Used to manage schizophrenia, reducing symptoms like hallucinations and delusions.
• Used for depression, particularly when other antidepressants have been ineffective.
• Effective in reducing anxiety and promoting better sleep in various mental health conditions.
• Can help calm agitated or aggressive behavior in certain psychiatric disorders.
• Used as a sedative to induce relaxation and improve sleep patterns.
• Assists in managing mood disorders, ensuring a more stable emotional state.

To be taken as per doctor's prescription

In the case of an overdose of Quetiapine 100mg Tablets, several symptoms may occur. These can include severe drowsiness, rapid heartbeat, and difficulty breathing. The severity of the overdose effects can vary depending on the individual and the amount ingested. If an overdose is suspected, it is vital to seek medical assistance promptly. Quick action can ensure proper treatment and reduce the potential risks associated with overdosing on this medication.

In the case of a missed dose of Quetiapine 100mg Tablet, it is important to take the missed dose as soon as you remember, provided there is a sufficient gap until your next scheduled dose. If it is close to the time of your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It is advisable to set a daily routine to help you remember to take your medication at the same time each day to minimize the chances of missing a dose.

To take Quetiapine 100mg Tablets, swallow the tablet whole with a glass of water, preferably in the evening before bedtime, following the exact dosage instructions provided by your healthcare professional, without crushing, chewing, or breaking the tablet.

Here are the conditions or situations when Quetiapine 100mg Tablet should not be taken:

• Do not take if you are allergic to quetiapine or any other antipsychotic medications.
• Avoid if you have a history of stroke, mini-stroke, or circulation problems.
• Should not be used in individuals with certain eye conditions such as narrow-angle glaucoma.
• Contraindicated in patients with severe liver or kidney disease.
• Not suitable for people with certain blood disorders (e.g., low white blood cell count).
• Do not use if you have a personal or family history of Long QT syndrome.
• Should be avoided by individuals with uncontrolled seizures or epilepsy.
• Not recommended for patients with dementia-related psychosis.
• Do not take with alcohol or other central nervous system depressants.
• Avoid if you have a history of heart disease or low blood pressure.

The side effects of Quetiapine 100mg Tablet may include:

• Drowsiness or fatigue
• Dry mouth
• Increased appetite and weight gain
• Dizziness or lightheadedness
• Blurred vision
• Constipation
• Restlessness or agitation
• Muscle stiffness or tremors

Following are the precautions and warnings for Quetiapine 100mg Tablet:

• Do not abruptly stop taking this medication; gradually reduce the dosage as directed by your healthcare professional to prevent withdrawal symptoms.
• This medication may cause dizziness and lightheadedness, especially during the initial days of treatment. Avoid activities that require alertness until you know how this medicine affects you.
• Elderly patients may be more sensitive to the side effects, particularly drowsiness and confusion. Regular monitoring is necessary.
• Use with caution in patients with a history of seizures or conditions that increase the risk of seizures, as Quetiapine may lower the seizure threshold.
• It can cause changes in blood sugar levels; monitor blood glucose regularly, especially in diabetic patients.
• Avoid alcohol consumption while taking Quetiapine as it may intensify the side effects.
• This medication may cause weight gain and changes in cholesterol levels; regular monitoring is recommended.
• Quetiapine may increase the risk of suicidal thoughts or behaviors in children, teenagers, and young adults; close observation is essential during the initial treatment period.

Following are the drug interactions for Quetiapine 100mg Tablet:

• Concomitant use with other central nervous system depressants (e.g., benzodiazepines, opioids, alcohol) can increase sedation and respiratory depression.
• Quetiapine may enhance the effects of certain antipsychotic medications, leading to increased side effects.
• It can interact with medications metabolized by the liver's CYP450 enzymes, including some antidepressants and anticonvulsants, potentially altering their effectiveness.
• The effectiveness of quetiapine may be reduced when taken with strong CYP3A4 inducers like carbamazepine or phenytoin.
• Antihistamines and medications for Parkinson's disease may have additive effects when combined with quetiapine, leading to increased drowsiness.
• Antihypertensive drugs may have their effects enhanced by quetiapine, potentially causing a significant drop in blood pressure.
• Caution is advised when combining quetiapine with anticoagulants, as it may increase the risk of bleeding.
• Diabetes medications may require dose adjustments when taken with quetiapine due to potential changes in blood sugar levels.

Following are the food interactions for Quetiapine 100mg Tablet:

• Avoid drinking grapefruit juice or eating grapefruit as it can increase the concentration of Quetiapine in the blood, potentially leading to increased side effects.
• Alcohol consumption should be minimized or avoided as it can enhance the sedative effects of Quetiapine, causing excessive drowsiness and dizziness.
• Consuming a high-fat meal before taking Quetiapine may slightly decrease its absorption, but this effect is generally not clinically significant.
• Avoid caffeine or reduce intake, as it can interact with Quetiapine, increasing the risk of side effects like nervousness, rapid heart rate, and sleep disturbances.
• Foods rich in tyramine, such as aged cheeses, cured meats, and certain types of beer, should be limited as they may interact with Quetiapine, leading to elevated blood pressure.
• Avoid or limit the consumption of foods that are highly acidic, as they may potentially interfere with the absorption of Quetiapine.
• Always take the medication with a full glass of water to ensure proper dissolution and absorption.
• Consult your healthcare provider for personalized advice on dietary considerations while taking Quetiapine.

Quetiapine 100mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to expose the tablets to extreme temperatures, so avoid storing them in hot or humid environments like bathrooms or kitchens. Always check the expiration date before use, and never use the medication if it is past its expiry. For proper disposal, do not flush the tablets or throw them into the trash; instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep the medication securely stored away from children and pets to prevent accidental consumption.

No

Following are the quick tips for Quetiapine 100mg Tablet:

• Take the tablet as directed by your doctor, typically once daily in the evening.
• Swallow the tablet whole with a glass of water, do not crush or chew.
• You can take it with or without food, but be consistent.
• Avoid alcohol while on this medication as it may intensify side effects.
• Do not stop taking the medication without consulting your doctor.
• If you experience excessive sleepiness or dizziness, inform your doctor.
• Store the tablets in a cool, dry place, away from direct sunlight.