Ramipace (1.25mg) 28 Tablet

Ramipril 1.25mg Tablet primarily exerts its therapeutic effects through the inhibition of the angiotensin-converting enzyme (ACE). By blocking ACE, the medication interrupts the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. This inhibition leads to decreased angiotensin II levels, resulting in reduced vasoconstriction and lowered blood pressure. Additionally, the reduced angiotensin II levels stimulate the release of aldosterone, contributing to a decrease in blood pressure by promoting sodium and water excretion, and potassium retention.

Angiotensin-converting enzyme (ACE) inhibitor.

Tablet

The following are the uses of Ramipril 1.25mg Tablet:

• Used for treating high blood pressure, helping to control and manage hypertension.
• Used to improve heart function and reduce the workload on the heart after a heart attack.
• Used in treating heart failure, aiding in symptom relief and improving overall heart health.
• Used to prevent further cardiovascular issues in patients with a history of heart disease.
• Used for kidney protection in diabetic patients, reducing the risk of kidney complications.
• Used to lower the risk of stroke and heart-related events in high-risk individuals.
• Used to manage certain chronic pain conditions, particularly in diabetic neuropathy.

Dosage is based on your medical condition and response to treatment

In the case of an overdose of Ramipril 1.25mg Tablets, symptoms may include severe dizziness, extremely low blood pressure, and increased heart rate. Promptly seek medical attention if you suspect an overdose, as it can lead to a medical emergency. Treatment for an overdose may involve supportive measures such as monitoring vital signs, ensuring adequate hydration, and administering medications to counteract the effects of the drug if necessary. It is crucial to act quickly and seek professional help.

In the case of a missed dose of Ramipril 1.25mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting an alarm or using a pill organizer to help you remember to take your medication at the same time each day. Consult your healthcare provider if you have any concerns or questions about managing missed doses.

To take Ramipril 1.25mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, as directed by your healthcare professional.

Here are the conditions and situations when Ramipril 1.25mg Tablet should not be taken:

• Should not be used in individuals with a known allergy to Ramipril or any ACE (angiotensin-converting enzyme) inhibitors.
• Contraindicated in pregnant women, especially during the second and third trimesters.
• Should not be used in patients with a history of angioedema, either hereditary or related to previous ACE inhibitor therapy.
• Not recommended for individuals with bilateral renal artery stenosis or unilateral stenosis in a solitary kidney.
• Contraindicated in patients with severe liver impairment or significant liver disease.
• Should not be used in individuals undergoing dialysis with high-flux membranes due to the risk of anaphylactoid reactions.
• Not suitable for patients with a history of severe hypotension (low blood pressure).
• Should be avoided in patients with untreated or uncontrolled kidney disease.

The side effects of Ramipril 1.25mg Tablet may include:

• Dizziness
• Lightheadedness
• Fatigue or weakness
• Dry cough
• Headache
• Nausea and vomiting
• Diarrhea
• Skin rash or itching

Following are the precautions and warnings for Ramipril 1.25mg Tablet:

• Do not start or continue Ramipril if you have a history of angioedema or hereditary angioedema; it can cause severe swelling of the face, throat, or tongue.
• Regular monitoring of kidney function is necessary, especially in patients with impaired kidney function or those on diuretic therapy.
• Patients with a history of liver disease should use this medication with caution, as it may affect liver function.
• Elderly patients may be more sensitive to the effects of Ramipril, particularly during the initial stages of treatment.
• Diabetic patients should monitor their blood sugar levels regularly, as Ramipril can cause fluctuations.
• Inform your doctor if you are pregnant or planning to become pregnant, as Ramipril may cause harm to the unborn baby.
• This medication may cause dizziness or lightheadedness, especially when standing up suddenly; exercise caution when performing tasks that require alertness.

Following are the drug interactions for Ramipril 1.25mg Tablet:

• Lithium levels can be increased by Ramipril, potentially leading to lithium toxicity. Regular monitoring of lithium levels is necessary.
• Combining Ramipril with diuretics, especially potassium-sparing diuretics, may cause hyperkalemia, requiring close monitoring of potassium levels.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) might reduce the antihypertensive effect of Ramipril and increase the risk of kidney dysfunction.
• Ramipril may enhance the blood pressure-lowering effect of other antihypertensive medications, including beta-blockers and calcium channel blockers.
• The risk of angioedema is elevated when Ramipril is used with angiotensin receptor blockers (ARBs) or other angiotensin-converting enzyme (ACE) inhibitors.
• The use of Ramipril with potassium supplements or potassium-containing salt substitutes can lead to hyperkalemia.
• Caution is advised when combining Ramipril with immunosuppressants, as it may increase the risk of infections and affect blood cell counts.

Following are the food interactions for Ramipril 1.25mg Tablet:

• Avoid consuming high-sodium foods like processed snacks, canned soups, and condiments. High sodium intake can reduce the medication's effectiveness.
• Potassium-rich foods like bananas, oranges, and spinach should be consumed in moderation as Ramipril may increase potassium levels.
• Avoid excessive alcohol consumption as it can lower blood pressure further, leading to dizziness and lightheadedness.
• Grapefruit and grapefruit juice should be limited as they may increase the levels of Ramipril, affecting blood pressure control.
• Maintain a balanced diet with whole grains, lean proteins, and healthy fats to support overall cardiovascular health.
• Avoid or limit foods with high levels of tyramine, such as aged cheeses, cured meats, and fermented foods, as they may interact with Ramipril.
• Stay hydrated by drinking plenty of water, as dehydration can affect blood pressure regulation.

Ramipril 1.25mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to contaminants. Avoid storing them in the bathroom or near heat-emitting appliances as temperature fluctuations can impact the medication's effectiveness. Dispose of any unused or expired tablets responsibly; do not flush them or pour them down the drain. Consult your pharmacist or healthcare provider for appropriate disposal methods to minimize environmental impact. Always keep medications out of children's reach to prevent accidental consumption.

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Following are the quick tips for Ramipril 1.25mg Tablet:

• Start with a low dose and gradually increase as directed by your doctor.
• Take the tablet at the same time each day to maintain consistent blood levels.
• Swallow the tablet whole with a full glass of water, preferably on an empty stomach.
• Avoid salt substitutes or potassium supplements unless advised by your doctor.
• Regularly monitor your blood pressure and kidney function while on this medication.
• Inform your doctor about all medications you are taking to avoid potential interactions.
• Do not stop taking the medication without consulting your healthcare provider.