Requip (0.25mg) 21 Tablets

Requip (0.25mg) 21 Tablets

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  • Manufacturer GSK
  • Generic Name Ropinirole

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Laboratory Screening
  • Description

    Ropinirole, at a dosage of 0.25mg, exerts its therapeutic effects primarily by acting as a dopamine agonist. It binds to and stimulates dopamine receptors, specifically the D2 and D3 subtypes, in the brain. This mechanism mimics the action of dopamine, a neurotransmitter involved in various physiological processes, including motor control and reward pathways. By activating these dopamine receptors, ropinirole can alleviate symptoms associated with dopamine deficiency, such as in Parkinson's disease. This selective activation of dopamine receptors is responsible for the drug's effectiveness in treating movement disorders, as it helps restore the balance of dopamine in the brain and improves motor function.

  • Ingredients

    Ropinirole
  • Drug Class

    Dopamine agonist.

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Ropinirole 0.25mg Tablet:

    • Used for managing symptoms of Parkinson's disease, providing relief from motor fluctuations.
    • Used to treat restless legs syndrome, reducing discomfort and improving sleep.
    • Used in dopamine agonist therapy to regulate dopamine levels in the brain.
    • Used to alleviate involuntary movements and stiffness associated with Parkinson's.
    • Used for improving overall mobility and quality of life in Parkinson's patients.
    • Used as a long-term treatment option with gradual dosage adjustments.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • For the treatment of Parkinson's disease, the recommended dose is typically 2-4 mg per day divided into 3 doses. The lowest dose possible that provides adequate control of symptoms should be used.
    • For the treatment of Restless Legs Syndrome (RLS), the recommended dose is typically 0.25-0.5 mg per day.
    • Gradually reduce the dose before stopping entirely to prevent withdrawal symptoms.
    • Please consult your physician for specific dosage regimens as it depends on the severity of the disease, response to the medication, and individual tolerance.
  • In case of Overdose

    In the case of an overdose of Ropinirole 0.25mg Tablets, symptoms may include severe nausea, vomiting, fainting, and dizziness. Overdose can lead to hypotension and extreme drowsiness. If you suspect an overdose, seek medical advice immediately. Prompt treatment can help manage symptoms and prevent potential complications, so ensure you contact a healthcare professional without delay. It is crucial to recognize the signs of overdose and take appropriate action to ensure the individual's safety and well-being.

  • Missed Dose

    In the case of a missed dose of Ropinirole 0.25mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen. It is crucial to maintain a consistent dosing schedule for the medication to be most effective.

  • How To Use

    To take Ropinirole 0.25mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, typically starting with a low dose and gradually increasing as directed.

  • When Not to Use

    Following are the conditions when Ropinirole 0.25mg Tablet should not be used:

    • Should not be taken by individuals with a known allergy to Ropinirole or any of its ingredients.
    • Not suitable for patients with severe kidney disease or end-stage renal disease.
    • Contraindicated in individuals with severe uncontrolled high blood pressure.
    • Should not be used in patients with a history of severe heart disease or heart failure.
    • Not recommended for individuals with a history of psychotic disorders or severe mental health conditions.
    • Contraindicated during pregnancy or if planning to become pregnant, as it may cause harm to the unborn baby.
    • Should not be used in women who are breastfeeding, as it can pass into breast milk.
    • Not suitable for children and adolescents under 18 years of age.
    • Should be avoided if you have a history of low blood pressure or orthostatic hypotension.
  • Side Effects

    The side effects of Ropinirole 0.25mg Tablet may include:

    • Nausea and vomiting
    • Dizziness and lightheadedness
    • Fatigue and drowsiness
    • Dry mouth
    • Constipation
    • Leg cramps
    • Unusual dreams
    • Behavioral changes (such as increased gambling or sexual urges)
  • Precautions & Warnings

    Following are the precautions and warnings for Ropinirole 0.25mg Tablet:

    • Do not start or stop taking this medication without consulting your doctor, especially if you have a history of kidney or liver disease.
    • This medication may cause sudden sleep attacks, so caution is advised when performing activities that require alertness, such as driving or operating machinery.
    • Elderly patients may be more sensitive to the side effects, so dosage adjustments might be necessary.
    • Patients with a history of heart problems, low blood pressure, or fainting spells should exercise caution as this drug can lower blood pressure.
    • It may cause impulse control problems such as compulsive gambling, shopping, or increased sexual urges. Seek medical advice if you experience these symptoms.
    • Inform your doctor if you have a history of mental health disorders, as this medication may cause hallucinations or confusion.
    • Pregnant or breastfeeding women should consult their doctor before taking this medication, as it may have potential risks for the baby.
  • Drug Interactions

    Following are the drug interactions for Ropinirole 0.25mg Tablet:

    • Concomitant use with dopamine agonists or antagonists may lead to altered effects, as ropinirole is a dopamine agonist.
    • Taking ropinirole with medications that cause drowsiness, such as opioids, benzodiazepines, or certain antidepressants, can increase the risk of sedation and dizziness.
    • It may interact with antihypertensive drugs, potentially causing a decrease in blood pressure.
    • Caution is advised when combining ropinirole with antipsychotics, as it may increase the risk of psychotic symptoms.
    • Alcohol consumption can enhance the sedative effects of ropinirole, affecting alertness and coordination.
    • Ropinirole may interact with certain anti-nausea medications, potentially affecting their effectiveness.
    • The effects of ropinirole may be altered when taken with medications that affect liver function, as the liver plays a role in its metabolism.
  • Food Interactions

    Following are the food interactions for Ropinirole 0.25mg Tablet:

    • Alcohol consumption should be avoided as it may increase the risk of dizziness, drowsiness, and sleepiness.
    • Grapefruit and grapefruit juice are to be avoided as they can alter the drug's effect, increasing Ropinirole levels in the blood.
    • Fava beans, also known as broad beans, should be consumed with caution as they can reduce the drug's effectiveness.
    • Caffeine intake should be monitored as it can worsen Ropinirole's side effects, especially restlessness and agitation.
    • High-protein meals may decrease Ropinirole's absorption, so it is advisable to take the medication on an empty stomach or with a light, low-protein meal.
    • Avoid consuming natural licorice, as it may increase the risk of side effects due to its potential interaction with Ropinirole.
    • Be cautious with mature cheese consumption, as it can contain a substance that may interfere with the medication's metabolism.
    • Follow healthcare provider's advice regarding dietary restrictions or recommendations specific to your condition.
  • Storage/Disposal

    Ropinirole 0.25mg Tablets should be stored in a secure and dry location, maintaining a consistent room temperature. It is crucial to keep the tablets in their original packaging, ensuring the container remains tightly sealed to prevent exposure to moisture or air. Avoid placing the medication in the bathroom or near heat-emitting appliances, as temperature fluctuations can impact its effectiveness. Prior to administration, carefully inspect the packaging for any signs of tampering or damage. Once the tablets are no longer required, it is essential to dispose of them in a safe and environmentally responsible manner. Never flush medications down the toilet or pour them into drainage systems. Instead, consult with a pharmacist or healthcare professional for guidance on the appropriate disposal methods in your area. Additionally, exercise caution to keep the medication out of children's reach to prevent accidental ingestion.

  • Quick Tips, if any

    Following are the quick tips for Ropinirole 0.25mg Tablet:

    • Start with a low dose and gradually increase as directed by your doctor to minimize side effects.
    • Take the tablet at the same time each day to maintain consistent levels.
    • Swallow the tablet whole with a full glass of water, preferably with or after meals.
    • Do not crush, chew, or break the tablet to ensure proper absorption.
    • Avoid alcohol consumption while taking this medication to prevent adverse interactions.
    • Inform your doctor about all medications/supplements you are using to prevent potential drug interactions.
    • Store the medication in a cool, dry place, away from direct sunlight and moisture.
  • Laboratory Screening

    Ropinirole is a prescription medication that treats symptoms of Parkinson's disease and Restless Leg Syndrome (RLS). When taking ropinirelle, there are several important health tests and assessments to consider, as advised by a physician or healthcare provider. These depend on individual factors such as age, other medical conditions, and medication allergies. Monitoring liver function is crucial since ropinirelle is metabolized by the liver and long-term use may lead to liver injury. Regular liver function tests check for signs of toxicity. A complete blood count (CBC) is advisable to monitor blood cell count changes that may indicate internal bleeding or bone marrow problems. Given that ropinirelle can cause dizziness and somnolence, it is important to assess kidney function, glucose levels, and perform a urinalysis to check for sugar or protein in the urine, which may indicate diabetes or kidney disorders. Since the drug can impact blood pressure and heart rate, it is important to monitor blood pressure and electrocardiogram (EKG) readings to check for abnormal heart rhythms. It is necessary to note that consulting a physician or healthcare provider is crucial to determining which specific lab tests are required based on individual needs and concerns.

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