Rumadol (500/30/2mg) 100 Tablets

Paracetamol 2mg Tablet works primarily by inhibiting the synthesis of prostaglandins, which are involved in the mediation of pain and inflammation in the body. It acts on specific enzymes called cyclooxygenase (COX) enzymes, particularly COX-2, which play a crucial role in the production of prostaglandins. By blocking these enzymes, paracetamol reduces the production of prostaglandins, leading to decreased pain and fever. The exact mechanism by which paracetamol selectively inhibits COX-2 is not fully understood, but it is believed to involve interactions with specific binding sites on the enzyme, thereby preventing the conversion of arachidonic acid into prostaglandin precursors. This action helps in reducing the perception of pain and lowering elevated body temperature.

Analgesic, antipyretic

Tablet

The following are the uses of Paracetamol 2mg Tablet:

• Used for relieving mild to moderate pain such as headaches, toothaches, and menstrual cramps.
• Used for reducing fever and managing discomfort associated with colds and flu.
• Used for easing aches and pains related to muscle strains and sprains.
• Used for providing symptomatic relief in conditions like arthritis and back pain.
• Used for managing post-vaccination fever and discomfort.
• Used for treating pain and fever in children, under medical supervision.
• Used as an adjunct to other medications for comprehensive pain management.
• Used to improve overall well-being by reducing pain and inflammation.

In the case of an overdose of Paracetamol 2mg Tablets, individuals may experience symptoms such as nausea, vomiting, abdominal pain, and potential liver damage. The severity of the effects depends on the amount ingested. It is important to seek medical advice promptly if an overdose is suspected. Treatment may involve gastric decontamination, supportive care, and monitoring of liver function. Prompt recognition and intervention are crucial to managing the potential health risks associated with Paracetamol overdose.

In the case of a missed dose of Paracetamol 2mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication and adjust your dosing schedule. It is essential to follow the prescribed dosage instructions for Paracetamol to ensure its effectiveness and minimize the risk of side effects.

To take Paracetamol 2mg Tablet, swallow the tablet whole with a glass of water, following the dosage instructions provided by your healthcare professional, typically one tablet every 4 to 6 hours, with a maximum of 4 tablets in 24 hours.

Here are the conditions or situations when Paracetamol 2mg Tablet should not be used:

• Do not take if you have a known allergy or hypersensitivity to paracetamol or any of the tablet's components.
• Avoid if you have severe liver or kidney disease, as the medication's metabolism may be affected.
• Not suitable for individuals with G6PD (Glucose-6-Phosphate Dehydrogenase) deficiency.
• Contraindicated in patients with acute liver failure or severe hepatic impairment.
• Avoid prolonged use without medical supervision, as it may lead to liver damage.
• Do not exceed the recommended dosage, as it may cause severe skin reactions and other adverse effects.
• Not recommended for individuals with alcohol dependency or chronic alcohol consumption.

The side effects of Paracetamol 2mg Tablet may include:

• Nausea and vomiting
• Loss of appetite
• Stomach pain
• Sweating
• Fatigue and weakness
• Dark-colored urine
• Yellowing of skin or eyes (jaundice)
• Allergic reactions (such as rash, itching, or swelling)

Following are the precautions and warnings for Paracetamol 2mg Tablet:

• This medication should not be used in patients with severe liver or kidney impairment without medical supervision, as it may require dosage adjustments.
• Paracetamol can cause liver damage if taken in excessive amounts or for prolonged periods. Do not exceed the recommended dosage.
• Alcohol consumption should be avoided or limited while taking this medication, as it may increase the risk of liver damage.
• If you are taking other medications containing paracetamol, ensure you do not exceed the maximum daily dose to prevent overdose.
• Patients with a history of allergic reactions to paracetamol or related compounds should not use this medication.
• Patients with a history of blood disorders or glucose-6-phosphate dehydrogenase (G6PD) deficiency should exercise caution and consult a doctor before use.
• Not recommended for long-term use without medical supervision. Consult a healthcare professional if symptoms persist or worsen.
• Always read the patient information leaflet provided with the medication for specific instructions and warnings.

Following are the drug interactions for Paracetamol 2mg Tablet:

• Alcohol may increase the risk of liver damage when taken with Paracetamol, especially with chronic, excessive alcohol consumption.
• Paracetamol can prolong the effect of anticoagulants like warfarin, potentially requiring adjustments in dosage.
• The effectiveness of Paracetamol may be reduced when taken with other pain relievers like ibuprofen or aspirin.
• It can interact with certain anti-epileptic drugs, such as phenytoin and carbamazepine, affecting their levels in the body.
• Prolonged use with metoclopramide or domperidone may increase the risk of side effects.
• When combined with cholestyramine, Paracetamol's absorption is reduced, potentially requiring alternative dosing.
• Concomitant use with isoniazid may increase the risk of liver damage, requiring careful monitoring.

Following are the food interactions for Paracetamol 2mg Tablet:

• Alcohol consumption should be avoided as it may increase the risk of liver damage, especially with long-term use.
• Grapefruit and grapefruit juice are generally safe to consume with Paracetamol, but in large quantities, they might inhibit liver enzymes and affect drug metabolism.
• Avoid high-fat meals as they can slow down the absorption of Paracetamol, potentially delaying its pain-relieving effects.
• Caffeine-rich foods and beverages should be limited as they may increase the metabolism of Paracetamol, reducing its effectiveness.
• Avoid foods rich in vitamin K (like leafy greens) if you're using Paracetamol for an extended period, as it may affect blood clotting.
• Consuming adequate water with the tablet is essential to ensure proper dissolution and absorption.
• Avoid excessive consumption of sugary foods, as Paracetamol is sometimes available in syrup form with a high sugar content.

Paracetamol 2mg Tablets should be stored in a cool, dry place, preferably at room temperature between 68°F and 77°F (20°C and 25°C). Protect the tablets from excessive heat, moisture, and direct sunlight, and keep them in their original container with the lid tightly closed to maintain their integrity. It is crucial to regularly check the expiration date on the packaging and dispose of any expired or unused tablets promptly. When disposing of Paracetamol, do not flush them down the toilet or throw them into the trash. Instead, follow local guidelines for medication disposal or consult a pharmacist for safe disposal options. Always keep medications out of the sight and reach of children and pets to prevent accidental consumption.

Following are the quick tips for Paracetamol 2mg Tablet:

• Consult a doctor or pharmacist before use, especially if you have liver or kidney issues.
• Take the tablet with a full glass of water, do not crush or chew.
• Maintain a gap of at least 4 hours between doses.
• Avoid alcohol consumption while taking this medication.
• Inform your doctor about all medications you are currently taking.
• Do not exceed the recommended dosage, and do not take for prolonged periods without medical advice.
• Store at room temperature, away from moisture and heat.